150 Results for "

thermosensitive ionic microgels

" in MedChemExpress (MCE) Product Catalog:
Products (150)

150 Results for "thermosensitive ionic microgels" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-125861D
CAS No.: 9004-67-5
Purity:  ≥98.0%
Synonyms: MC(Viscosity:40000mPa.s)
Methyl cellulose (MC) (Viscosity:40000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:40000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .
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2
2 Cited Publications
Cat. No.: HY-157131
CAS No.: 2242724-49-6
Purity:  99.84%
Target:  

TRP Channel

Research Areas:  

Neurological Disease

TRPV2-selective blocker 1 is a TRPV2-selective blocker that inhibits calcium influx and ionic currents. TRPV2-selective blocker 1 exhibits an IC50 of 6.3 μM against rat TRPV2, and shows no activity against TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 attenuates macrophage phagocytosis, LPS-induced macrophage migration, and calcium microdomains generated by peripheral TRPV2. TRPV2-selective blocker 1 is non-cytotoxic and can be used to investigate the function of TRPV2 during immune processes .
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2
2 Cited Publications
Cat. No.: HY-B1941
CAS No.: 140-66-9
4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .
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1
1 Cited Publications
Cat. No.: HY-125924
CAS No.: 474922-26-4
Purity:  99.96%
Synonyms: DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) Amine ammonium
Target:  

Drug Derivative

Research Areas:  

Cancer

DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
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1
1 Cited Publications
Cat. No.: HY-147246
CAS No.: 1868138-66-2
Purity:  99.34%
Synonyms: HTD1801; BUDCA
Research Areas:  

Metabolic Disease

Berberine ursodeoxycholate (HTD1801), an ionic salt of Berberine and Ursodeoxycholic acid, is an orally active and potent hypolipidemic agent. Berberine ursodeoxycholate shows significantly great reduction in liver fat content. Berberine ursodeoxycholate has a broad spectrum of metabolic activity. Berberine ursodeoxycholate can be used for the research of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes .
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1
1 Cited Publications
Cat. No.: HY-B1292
CAS No.: 606-17-7
Synonyms: Adipiodone
Research Areas:  

Inflammation/Immunology

Iodipamide (Adipiodone) is an ionic iodinated contrast agent. Iodipamide is used for diagnostic imaging to visualize the bile ducts and gallbladder during X-ray examinations .
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1
1 Cited Publications
Cat. No.: HY-W018749
CAS No.: 1702-17-6
Research Areas:  

Others

Clopyralid is a toxic and biorefractory herbicide. Clopyralid can form ionic liquids with increased efficacy against weeds and reduced leaching from soils .
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1
1 Cited Publications
Cat. No.: HY-B1699
CAS No.: 1949-45-7
Synonyms: Metrizoate
Metrizoic acid (Metrizoate) is an ionic contrast medium. Metrizoic acid (Metrizoate) shows high osmolality and has a risk of inducing allergic reactions .
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1
1 Cited Publications
Cat. No.: HY-B0952
CAS No.: 123-82-0
Synonyms: Tuaminoheptane
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

2-Aminoheptane (Tuaminoheptane) is a norepinephrine transporter inhibitor. 2-Aminoheptane binds to norepinephrine transporter via ionic and hydrophobic interactions to block norepinephrine uptake. 2-Aminoheptane deactivates ω-TAmla enzyme, reduces recombinant whole cell stability, and acts as an amino group donor substrate for ω-TA and ω-TAmla enzymes. 2-Aminoheptane can be used in research on depression and Alzheimer's disease .
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1
1 Cited Publications
Cat. No.: HY-148140
CAS No.: 9041-35-4
Research Areas:  

Others

Cross-linked dextran G 25 is a cross-linked dextran gel chromatography medium that possesses multiple separation activities, including molecular sieve effects, weak anion exchange, and aromatic adsorption. Cross-linked dextran G 25 weakly exchanges cations through immobilized terminal carboxyl groups and repels anions at low ionic strength. Cross-linked dextran G 25 is used for the fractionation of low molecular weight solutes, including peptides, amino acids, nucleotide sugar derivatives, and aromatic compounds .
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1
1 Cited Publications
Cat. No.: HY-132830
CAS No.: 1933514-13-6
Purity:  99.58%
Synonyms: KVD900
Target:  

Kallikrein

Research Areas:  

Cardiovascular Disease

Sebetralstat (KVD900) is an orally active and selective plasma kallikrein inhibitor, with an IC50 of 6.0 nM and a Ki of 3.0 nM against the human target. Sebetralstat binds to the active site of plasma kallikrein, inducing a conformational flip of Trp215 to form a U-shaped conformation; its P1 group interacts with the S1 pocket through hydrophobic interactions and displacement of high-energy water molecules, independent of the Asp189 ionic bond. Sebetralstat inhibits plasma kallikrein-kinin system activation in whole plasma, rapidly relieves laryngeal and abdominal attack symptoms of hereditary angioedema (HAE-C1INH), and reduces attack severity. Sebetralstat can be used in research related to hereditary angioedema (HAE) .
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Cat. No.: HY-A0104J
CAS No.: 9004-65-3
Synonyms: Hypromellose (Type II,Viscosity:5mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:5mPa.s); Celacol HPM 5000 (Type II,Viscosity:5mPa.s)
HPMC (Hypromellose) (Type II,Viscosity:5mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. HPMC (Type II,Viscosity:5mPa.s) is widely used in agent formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior .
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Cat. No.: HY-W110584
CAS No.: 24249-95-4
Carboxybetaine methacrylate is an amphoteric ionic compound with excellent properties such as good hydrophilicity, antistatic property, and biocompatibility. Carboxybetaine methacrylate can be used to prepare tissue engineering scaffolds, drug carriers, and so on .
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Cat. No.: HY-B1620B
CAS No.: 9003-39-8
Synonyms: PVP K15; Polyvidone K15; Povidone K15
Polyvinylpyrrolidone K15 is a linear non-ionic polymer devises vigorous bright crystalline layers and has adhesive, cohesive and dispersive properties .
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Cat. No.: HY-W129988
CAS No.: 1338-39-2
Sorbitan monododecanoate is a non-ionic surfactant, often used as an emulsifier in food, feed and topical preparations. Sorbitan monododecanoate can also be employed as a pharmaceutical excipient .
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Cat. No.: HY-101530C
CAS No.: 9004-99-3
Purity:  ≥98.0%
Synonyms: PEG 100 stearate
Polyoxyl 100 stearate (PEG-100 stearate) is a non-ionic surfactant formed by polyethylene glycol (PEG) and stearic acid, and it is commonly used in pharmaceutical preparations, nanocarriers, emulsification systems and cosmetic formulations .
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Cat. No.: HY-109079
CAS No.: 1902954-60-2
Purity:  99.86%
Synonyms: DWP14012; Fexuprazan
Target:  

Proton Pump

Research Areas:  

Metabolic Disease

Abeprazan (DWP14012) is a potassium-competitive acid blocker. Abeprazan inhibits H +, K +- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan is developed as a potential alternative to proton pump inhibitor for the treatment of acid-related diseases .
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Cat. No.: HY-109079A
CAS No.: 1902954-87-3
Purity:  99.87%
Synonyms: DWP14012 hydrochloride; Fexuprazan hydrochloride
Target:  

Proton Pump

Research Areas:  

Metabolic Disease

Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker. Abeprazan hydrochloride inhibits H +, K +- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan hydrochloride is developed as a potential alternative to proton pump inhibitor for the treatment of acid-related diseases .
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Cat. No.: HY-125940
CAS No.: 200880-41-7
Purity:  ≥98.0%
Synonyms: 1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium
Target:  

Liposome

Research Areas:  

Others

DPPG (UV radiation exposure) suffers cleavage of C―O, C=O and -PO2- bonds and loses monolayer stability; when DNA exists in the subphase, ionic degradation products from DPPG and DNA stabilize intact DPPG molecules and mitigate UV irradiation damage .
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Cat. No.: HY-W250168A
CAS No.: 9004-98-2
Synonyms: Polyethylene glycol oleyl ether, average Mn~1150; Polyethylene glycol monooleyl ether, n~20
Polyoxyethylene(20) oleyl ether (Polyethylene glycol oleyl ether, with an average Mn of 1150) is a non-ionic surfactant. Polyoxyethylene(20) oleyl ether possesses emulsifying and detergent properties and can be used as a functional additive in drug delivery systems, helping to form stable nanoemulsions .
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