672 Results for "

factor-1

" in MedChemExpress (MCE) Product Catalog:
Products (672)

672 Results for "factor-1" in MCE Product Catalog:

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Cat. No.: HY-P3054
CAS No.: 93674-74-9
Research Areas:  

Cardiovascular Disease

S6 peptide is a potentially important lamin kinase. S6 peptide is involved in the process of cardiac hypertrophy induced by mechanical loading. S6 peptide can be activated by many kinds of growth factors .
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Cat. No.: HY-100872R
CAS No.: 342639-96-7
Research Areas:  

Cancer

KRIBB11 (Standard) is the analytical standard of KRIBB11 (HY-100872). This product is intended for research and analytical applications. KRIBB11 is an inhibitor of Heat shock factor 1 (HSF1), with IC50 of 1.2 μM.
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Cat. No.: HY-108963
CAS No.: 99682-33-4
Research Areas:  

Cancer

LY 170198 is a protein kinase C inhibitor and a LTD4 antagonist. LY 170198 is promising for research of tumor promotion, oncogene activation, protein phosphorylation, feedback mechanisms in signal transduction and cellular responses to growth factors .
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Cat. No.: HY-117997
CAS No.: 1635437-39-6
Purity:  ≥99.0%
Research Areas:  

Cancer

UMB-32, a potent, selective BRD4 inhibitor, binds BRD4 with the Kd of 550 nM, and IC50 of 637 nM. UMB-32 also shows potency against TAF1, a bromodomain-containing transcription factor .
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Cat. No.: HY-P1236
CAS No.: 88898-17-3
Synonyms: Atrial natriuretic factor (1-28) (rat, mouse)
Target:  

Endothelin Receptor

Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.
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Cat. No.: HY-10984S1
CAS No.: 2093128-28-8
Purity:  ≥99.0%
Synonyms: CC-4047-d3
Pomalidomide-d3 is the deuterium labeled Pomalidomide. Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors .
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Cat. No.: HY-108868
CAS No.: 492-18-2
Purity:  ≥80.0%
Synonyms: Salirgan; Salurin; Salyrgan
Research Areas:  

Metabolic Disease

Mersalyl (Salirgan) is a potent vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1 (HIF-1) inducer. Mersalyl induces VEGF and ENO1 mRNA expression. Mersalyl shows diuresis effects [1] .
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Cat. No.: HY-P811109
Synonyms: ETS-related transcription factor Elf-1, E74-like factor 1, ELF1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse

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Cat. No.: HY-P811803A
Synonyms: Embryonic growth/differentiation factor 1, GDF-1, GDF1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human

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Cat. No.: HY-16187
CAS No.: 1233948-61-2
Research Areas:  

Cancer

EL-102 is a hypoxia-induced factor 1 (Hif1α) inhibitor. EL-102 induces apoptosis, inhibits tubulin polymerisation and shows activities against prostate cancer. EL-102 can be used for the research of cancer [1].
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Cat. No.: HY-174541
Target:  

mRNA

Research Areas:  

Cancer

Human RUNX1 mRNA encodes the human RUNX family transcription factor 1 (RUNX1) protein, the alpha subunit of Core binding factor (CBF). RUNX1 can forms the heterodimeri CBF with CBFB and is thought to be involved in the development of normal hematopoiesis.
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Cat. No.: HY-188106
Target:  

mRNA

Research Areas:  

Metabolic Disease

Human IGF1 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating human IGF1 mRNA. Human IGF1 mRNA encapsulates human insulin-like growth factor 1 (IGF1) protein, which is involved in mediating growth and development.
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Cat. No.: HY-P99197
CAS No.: 943453-46-1
Synonyms: CP-751871

Target:  

IGF-1R

Research Areas:  

Cancer

Figitumumab (CP-751871) is a potent and fully human monoclonal anti–insulin-like growth factor 1 receptor (IGF1R) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC50 of 1.8 nM [1].
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Cat. No.: HY-P1236A
Synonyms: Atrial natriuretic factor (1-28) (rat, mouse) TFA
Target:  

Endothelin Receptor

Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse (TFA) is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.
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Cat. No.: HY-168624
CAS No.: 3050683-29-6
Target:  

Molecular Glues

Research Areas:  

Inflammation/Immunology

VAV1 degrader-2 is a molecular glue degrader based on targeting Vav guanine nucleotide exchange factor 1 (VAV 1) with a DC50 of 4.41 nM. VAV1 degrader-2 can be used in the study of inflammatory and autoimmune diseases [1].
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Cat. No.: HY-174778
Target:  

mRNA

Research Areas:  

Neurological Disease

Human ASCL1 mRNA encodes the human achaete-scute family bHLH transcription factor 1 (ASCL1) protein, a member of the basic helix-loop-helix (BHLH) family. ASCL1 plays a role in the neuronal commitment and differentiation, and in the generation of olfactory and autonomic neurons.
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Cat. No.: HY-N17756
CAS No.: 30655-48-2
Withanolide D (Compound 2) is a steroidal ester found in Withania somnifera (L.) Dunal, with anticancer activity. Withanolide D can activate the heat-shock factor 1 (HSF1)-dependent stress response. Withanolide D can be used for the research of cancer such as lymphoma [1].
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Cat. No.: HY-P4657
CAS No.: 96827-07-5
Target:  

Inhibitory Antibodies

Research Areas:  

Endocrinology

Human Growth Hormone (1-43) is an N-terminal fragment of human growth hormone with specific and pronounced insulin-like activity. Human Growth Hormone (1-43) can be used to study the function and metabolic pathways of growth hormone, a potential obesity-related factor .
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Cat. No.: HY-P991134
CAS No.: 2832924-76-0
Synonyms: VRDN-003; ZL-1109

Target:  

IGF-1R

Research Areas:  

Inflammation/Immunology

Elegrobart is an immunoglobulin G1-κ monoclonal antibody targeting the human insulin-like growth factor 1 receptor (IGF1R). Elegrobart is promising for research of diseases associated with abnormal IGF1R signaling, especially thyroid eye disease [1].
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Cat. No.: HY-162463
CAS No.: 3033235-42-3
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Ir-UA is an usnic acid-derived iridium(III) complex that enhances PD-L1 expression and converts "cold tumors" into "hot tumors." Ir-UA stimulates PD-L1 expression by explicitly regulating the PD-L1 transcription factor .
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