Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
83 Results for "
Cd38
" in MedChemExpress (MCE) Product Catalog:
Products (83)
83 Results for "Cd38" in MCE Product Catalog:
Cat. No.: HY-P70044
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P70022
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Human
Source:
HEK293
Cat. No.: HY-P78650
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Human
Source:
HEK293
Cat. No.: HY-P701286
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Human
Source:
HEK293
Cat. No.: HY-P704262
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Human
Source:
HEK293
Cat. No.: HY-P70074
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P70731A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Human
Source:
HEK293
Cat. No.: HY-P70731
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Human
Source:
HEK293
Cat. No.: HY-P704467
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Human
Source:
HEK293
Cat. No.: HY-181543
CAS No.: 2925663-26-7
Target:
Research Areas:
CVN14 is a potent, selective and brain-penetrant CD38 inhibitor with human IC50 19 nM, mouse IC50 2.4 nM. CVN14 binds uncompetitively to form a complex with CD38 and ADPR, and inhibits CD38 enzymatic activity. CVN14 can be used for the research of neurodegenerative diseases .
Cat. No.: HY-P992455
Target:
Research Areas:
Cat. No.: HY-P991913
Synonyms: TSK011010
Target:
Research Areas:
Cat. No.: HY-P72896
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Rabbit
Source:
HEK293
Cat. No.: HY-P72897
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Rat
Source:
HEK293
Cat. No.: HY-P72732
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cd38; NAD(+) Nucleosidase; Cd38 Molecule; Cd38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Di
Species:
Mouse
Source:
HEK293
Cat. No.: HY-184021
Target:
Research Areas:
A-8531 is an orally active CD38 inhibitor with IC50 values of 1.10 nM against human CD38, IC50 values of 2.93 nM against mouse CD38, and a human Ka of 0.32 nM. A-8531 exerts its inhibitory activity via its 4-pyridine reactive warhead interacting with the CD38 substrate NAD +, and binds stably to CD38 only in the presence of NAD +, with a binding KD of 0.32 nM as detected by SPR. A-8531 dose-dependently increases NAD + levels in mouse skin, lung and liver tissues, while simultaneously reducing the contents of NAM and ADPR in these tissues. A-8531 derivative A-3190 (HY-184206) has blood-brain barrier penetration. A-8531 can be used in studies related to neurodegenerative diseases .
Cat. No.: HY-P991914
Cat. No.: HY-182345
NOTA-MK0159 is a NOTA (HY-134418) and MK0159 (HY-150508) conjugate. NOTA-MK0159 inhibits human and mouse CD38 with IC50 values of 72.58 and 7.55 nM. NOTA-MK0159 coupled with radioactive elements acts as a imaging agent with specific uptake in CD38-positive multiple myeloma cells, enabling noninvasive whole-body assessment of CD38 expression in multiple myeloma xenografts. NOTA-MK0159 can be used for the research of multiple myeloma .
Cat. No.: HY-184206
Target:
Research Areas:
A-3190 is an orally active, blood-brain barrier permeable CD38 inhibitor, with an IC50 of 7.25 nM against human CD38 and 1.24 nM against mouse CD38. A-3190 is a derivative of A-8531 (HY-184021), and it forms covalent adducts with NAD + in the presence of CD38. A-3190 acts as an inducer of NAD + levels and an inhibitor of NAM and ADPR levels. A-3190 increases NAD + levels in the skin, lung, liver and brain of rodents, while reducing NAM and ADPR levels in brain tissues. A-3190 can be used in research related to multiple sclerosis, Parkinson's disease and Alzheimer's disease .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
