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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
55 Results for "
MDS
" in MedChemExpress (MCE) Product Catalog:
Products (55)
55 Results for "MDS" in MCE Product Catalog:
Cat. No.: HY-186044
CAS No.: 2654078-52-9
Target:
Research Areas:
Menin-MLL-IN-36 (compound 398) is an inhibitor of menin/MLL protein/protein interaction with an IC50 value of 0.043 μM in MEIS1 mRNA expression. Menin-MLL-IN-36 can be used in the research of cancer, myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), and diabetes .
Cat. No.: HY-P71222A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPCDC; PPC-DC; Phosphopantothenoylcysteine Decarboxylase; CoaC; MDS018; COAC; FLJ14585
Species:
Human
Source:
E. coli
Cat. No.: HY-P75549
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: YWHAE; Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon; 14-3-3 Protein Epsilon; Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein; Epsilon Polypeptide; 14-3-3 Epsilon; FLJ45465; 14-3-3E; Tyrosine 3/Trypt
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P811667
Synonyms: EVI1, MDS1, PRDM3, MECOM, Histone-lysine N-methyltransferase MECOM, Ecotropic virus integration site 1 protein homolog, MDS1 and EVI1 complex locus protein, Myelodysplasia syndrome 1 protein, Myelodysplasia syndrome-associated protein 1, EVI-1
Cat. No.: HY-P811883
Synonyms: MRPS28, HDCMD11P, MDS023, PSEC0213, MRPS35, Small ribosomal subunit protein mS35, MRP-S28, S28mt, MRP-S35, S35mt
Cat. No.: HY-P811883A
Synonyms: MRPS28, HDCMD11P, MDS023, PSEC0213, MRPS35, Small ribosomal subunit protein mS35, MRP-S28, S28mt, MRP-S35, S35mt
Cat. No.: HY-16782A
CAS No.: 1416216-01-7
Synonyms: ARRY-614 hydrochloride
Research Areas:
Pexmetinib hydrochloride (ARRY-614 hydrochloride) is an orally active dual Tie-2 and p38 MAPK inhibitor. Pexmetinib hydrochloride binds to Tie-2 and p38 MAPK in a "DFG-out" conformation, attenuates the phosphorylation of p38, inhibits STAT3 activation, reduces the promoter-binding activity of NFATc1, and decreases the expression of MMPs. Pexmetinib hydrochloride inhibits leukemia cell proliferation, abrogates TNF-α-mediated myelosuppression of healthy hematopoietic stem cells, stimulates hematopoiesis in primary myelodysplastic syndrome (MDS) samples, inhibits RANKL-induced osteoclast formation and bone resorption, and suppresses migration, invasion and induced osteolysis of breast cancer cells. Pexmetinib hydrochloride can be used in research related to myelodysplastic syndrome, acute myeloid leukemia and breast cancer-induced osteolysis .
Cat. No.: HY-P703355
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRDM16; MDS1/EVI1-Like Gene 1; PR/SET Domain 16; PR Domain 16; PFM13; MGC166915; MEL1; [Histone H3]-Lysine(9) N-Methyltransferase; Transcription Factor MEL1; PR-Domain Zinc Finger Protein 16; KIAA1675; PR Domain-Containing Protein 16; KMT8F; Alternative P
Species:
Human
Source:
E. coli
Cat. No.: HY-P86770
Synonyms: ALS2CR1 antibody; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 1 antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein antibody; CALS-7 antibody; MDS015 antibody; Ngg1 interacting factor 3-like 1 antibody; NIF3 (Ngg1 interacting factor 3, S.pombe homolog)-like 1 antibody; NIF3 NGG1 interacting factor 3-like 1 (S. pombe) antibody; NIF3 NGG1 interacting factor 3-like 1 antibody; NIF3-like protein 1 antibody; ALS2CR1 antibody; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 1 antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein antibody; CALS-7 antibody; MDS015 antibody; Ngg1 interacting factor 3-like 1 antibody; NIF3 (Ngg1 interacting factor 3, S.pombe homolog)-like 1 antibody; NIF3 NGG1 interacting factor 3-like 1 (S. pombe) antibody; NIF3 NGG1 interacting factor 3-like 1 antibody; NIF3-like protein 1 antibody; NIF3L_HUMAN antibody; Nif3l1 antibody; OTTHUMP00000206190 antibody; OTTHUMP00000206191 antibody; OTTHUMP00000206192 antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
