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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
95 Results for "
cIAP
" in MedChemExpress (MCE) Product Catalog:
Products (95)
95 Results for "cIAP" in MCE Product Catalog:
Cat. No.: HY-128812A
CAS No.: 1239866-59-1
Synonyms: E3 ligase Ligand-Linker Conjugates 33 Hydrochloride
Research Areas:
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 Hydrochloride can be used to design SNIPERs .
Cat. No.: HY-128813
CAS No.: 1225433-96-4
Synonyms: E3 ligase Ligand-Linker Conjugates 34
Research Areas:
cIAP1 Ligand-Linker Conjugates 15 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 can be used to design SNIPERs .
Cat. No.: HY-128813A
CAS No.: 1225383-36-7
Synonyms: E3 ligase Ligand-Linker Conjugates 34 hydrochloride
Research Areas:
cIAP1 Ligand-Linker Conjugates 15 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 hydrochloride can be used to design SNIPERs .
Cat. No.: HY-128814
Synonyms: E3 ligase Ligand-Linker Conjugates 35 hydrochloride
Research Areas:
cIAP1 Ligand-Linker Conjugates 6 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 6 hydrochloride can be used to design SNIPERs .
Cat. No.: HY-128815
CAS No.: 1351169-40-8
Synonyms: E3 ligase Ligand-Linker Conjugates 36
Research Areas:
cIAP1 Ligand-Linker Conjugates 14 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 14 can be used to design SNIPERs .
Cat. No.: HY-128816
CAS No.: 1312302-14-9
Synonyms: E3 ligase Ligand-Linker Conjugates 37
Research Areas:
cIAP1 Ligand-Linker Conjugates 2 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 can be used to design SNIPERs .
Cat. No.: HY-128817
CAS No.: 2095244-52-1
Synonyms: E3 ligase Ligand-Linker Conjugates 38
Research Areas:
cIAP1 Ligand-Linker Conjugates 12 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 12 can be used to design SNIPERs .
Cat. No.: HY-128819
CAS No.: 2222354-20-1
Synonyms: E3 ligase Ligand-Linker Conjugates 40
Research Areas:
cIAP1 Ligand-Linker Conjugates 3 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 3 can be used to design SNIPERs .
Cat. No.: HY-128820
CAS No.: 2357114-75-9
Synonyms: E3 ligase Ligand-Linker Conjugates 41
Research Areas:
cIAP1 Ligand-Linker Conjugates 1 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 1 can be used to design SNIPERs .
Cat. No.: HY-128821
Synonyms: E3 ligase Ligand-Linker Conjugates 42
Research Areas:
cIAP1 Ligand-Linker Conjugates 4 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 4 can be used to design SNIPERs .
Cat. No.: HY-128822
Synonyms: E3 ligase Ligand-Linker Conjugates 43
Research Areas:
cIAP1 Ligand-Linker Conjugates 13 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 13 can be used to design SNIPERs .
Cat. No.: HY-128823
Synonyms: E3 ligase Ligand-Linker Conjugates 44
Research Areas:
cIAP1 Ligand-Linker Conjugates 7 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 7 can be used to design SNIPERs .
Cat. No.: HY-128824
Synonyms: E3 ligase Ligand-Linker Conjugates 45
Research Areas:
cIAP1 Ligand-Linker Conjugates 9 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 9 can be used to design SNIPERs .
Cat. No.: HY-128825
Synonyms: E3 ligase Ligand-Linker Conjugates 46
Research Areas:
cIAP1 Ligand-Linker Conjugates 8 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 8 can be used to design SNIPERs .
Cat. No.: HY-128826
Synonyms: E3 ligase Ligand-Linker Conjugates 47
Research Areas:
cIAP1 Ligand-Linker Conjugates 10 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 10 can be used to design SNIPERs .
Cat. No.: HY-128816A
Synonyms: E3 ligase Ligand-Linker Conjugates 37 (Hydrochloride)
Research Areas:
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 Hydrochloride can be used to design SNIPERs .
Cat. No.: HY-142621
CAS No.: 2669844-82-8
BCPyr is a PROTAC degrader targeting cIAP1 and BTK, with a Kd of 262 nM for human cIAP1, and Kd values of 262 nM and 692 nM for human BTK. BCPyr binds to the Bir3 domain of cIAP1, recruits BTK to cIAP1, and mediates the ubiquitination and degradation of BTK. BCPyr acts as a degrader, ternary complex stabilizer, cooperative binder, and higher-order assembly inducer. BCPyr can be used in studies related to leukemia and lymphoma .
Cat. No.: HY-111839
CAS No.: 135325-47-2
Synonyms: CRABP-II ligand 1
Research Areas:
ATRA-hydroxyimino (CRABP-II ligand 1), the Retinoic acid (ATRA)-based moiety, binds to cIAP1 ligand (Bestatin) via a linker to form SNIPER to degrade CRABP-II in IMR-32 cells .
Cat. No.: HY-111841
CAS No.: 1225383-38-9
Research Areas:
PROTAC CRABP-II Degrader-2 is a cellular retinoic acid-binding protein (CRABP-II) SNIPER degrader. PROTAC CRABP-II Degrader-2 hijacks the cIAP1 E3 ligase to induce ubiquitination and proteasomal degradation of CRABP-II. PROTAC CRABP-II Degrader-2 can be used for the research of neuroblastoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
