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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
73 Results for "
EP2
" in MedChemExpress (MCE) Product Catalog:
Products (73)
73 Results for "EP2" in MCE Product Catalog:
Cat. No.: HY-139120
CAS No.: 64625-54-3
Synonyms: 19(R)-Hydroxy PGE2; 19(R)-OH PGE2
Target:
Research Areas:
19(R)-hydroxy Prostaglandin E2 (19(R)-hydroxy PGE2) is found in the semen of primates, including man. It is a potent smooth muscle relaxant and a selective agonist for the EP2 receptor. It has an EC50 value of 200 nM for relaxing cat tracheal rings which express EP2 receptors.
Cat. No.: HY-10418R
CAS No.: 33458-93-4
Research Areas:
AH 6809 (Standard) is the analytical standard of AH 6809. This product is intended for research and analytical applications. AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor [2] .
Cat. No.: HY-172561
Target:
Research Areas:
15-Keto treprostinil sodium is an impurity in Treprostinil (HY-100441). Treprostinil is a potent DP1 and EP2 agonist .
Cat. No.: HY-158659
CAS No.: 2550393-38-7
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TG11-77 hydrochloride is a potent, selective, orally active and brain permeant EP2 antagonist, with a KB of 9.7 nM. TG11-77 hydrochloride inhibits PGE2-induced human EP2 receptor activation. TG11-77 hydrochloride exhibits anti-inflammatory activity. TG11-77 hydrochloride reduces delayed mortality and memory deficit [2].
Cat. No.: HY-118215
CAS No.: 1192760-33-0
Synonyms: AGN212409
Target:
Research Areas:
Aganepag ethanediol (AGN212409) is an EP2 (Prostaglandin Receptor) receptor agonist. Aganepag ethanediol may be used in anti-glaucoma research .
Cat. No.: HY-14898
CAS No.: 910562-15-1
Synonyms: SimenEPag
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AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM.
Cat. No.: HY-167103A
CAS No.: 433232-03-2
Synonyms: ONO-AE1-259
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Research Areas:
ONO-8815Ly (ONO-AE1-259) is a selective EP2 receptor agonist. ONO-8815Ly inhibits spontaneous uterine contractility .
Cat. No.: HY-14839A
CAS No.: 223490-49-1
Synonyms: CP 533536
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology
Evatanepag sodium is a non-prostanoid, potent and selective EP2 receptor agonist. Evatanepag sodium can induce local bone formation in vivo. Evatanepag sodium can be used in the research of fractures, bone defects, asthma [2].
Cat. No.: HY-19641
CAS No.: 148436-63-9
Research Areas:
AH13205 is a selective prostanoid EP2-receptor agonist. AH13205 causes concentration-related relaxations of Carbachol (HY-B1208)-contracted trachea. AH13205 causes dose-related protection against Histamine (HY-B1204)-induced increases in respiratory rate .
Cat. No.: HY-100441R
CAS No.: 81846-19-7
Synonyms: UT-15 (Standard)
Research Areas:
Treprostinil (Standard) is the analytical standard of Treprostinil. This product is intended for research and analytical applications. Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
Cat. No.: HY-16504R
CAS No.: 289480-64-4
Synonyms: UT-15 sodium (Standard)
Research Areas:
Treprostinil (sodium) (Standard) is the analytical standard of Treprostinil (sodium). This product is intended for research and analytical applications. Treprostinil (UT-15) sodium is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
Cat. No.: HY-N7748A
CAS No.: 132152-57-9
Cat. No.: HY-106699
CAS No.: 87440-45-7
Synonyms: CG 4203 sodium
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Taprostene sodium is a partial agonist at prostanoid prostacyclin (IP) receptors. Taprostene sodium interacts additively with Prostaglandin E2 (PGE2) (HY-101952), ONO-AE1-259 (selective EP2 agonist), and acetylcholine. Taprostene sodium exerts a significant cardioprotection .
Cat. No.: HY-118190
CAS No.: 1176541-11-9
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AL 8810 methyl ester is a prostaglandin F(2α) analog and a prostaglandin F(2α) receptor agonist. Can competitively antagonize the effects of the FP receptor agonist Fluprostenol (HY-108560). AL 8810 methyl ester has no significant potency against TP, DP, EP(2), EP(4) receptor subtypes in cell lines .
Cat. No.: HY-B0131A
CAS No.: 27930-45-6
Target:
Research Areas:
Alprostadil sodium is a prostaglandin receptor ligand that exhibits Ki values of 36, 10, 1.1, 2.1, and 33 nM for the EP1, EP2, EP3, EP4, and IP receptors in mice, respectively. It promotes vasodilation and inhibits platelet aggregation, making it a useful vasodilator for investigating peripheral vascular disease.
Cat. No.: HY-114822
CAS No.: 36614-31-0
Synonyms: PGA3
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Research Areas:
Prostaglandin A3 is a non-enzymatic dehydration product of prostaglandin E3 (PGE3). Prostaglandin A3 showed good affinity for canine EP2 and EP4 receptors with IC50 values of 120 and 20 nM, respectively. The Ki value of Prostaglandin A3 for human PPARγ was 188 μM [2] .
Cat. No.: HY-B0131S2
CAS No.: 2342573-59-3
Synonyms: Alprostadil-d9; PGE1-d9
Cat. No.: HY-136696
CAS No.: 53658-98-3
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Research Areas:
11-Deoxy-16,16-dimethyl-PGE2, a Prostaglandin E2 analog, is a EP2 and EP3 receptors agonist. 11-Deoxy-16,16-dimethyl-PGE2 protects proximal renal tubular epithelial cells from potent nephrotoxicity-induced cell damage by exerting anti-oxidative stress [2].
Cat. No.: HY-B0131S
CAS No.: 211105-33-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
