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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
73 Results for "
FASN
" in MedChemExpress (MCE) Product Catalog:
Products (73)
73 Results for "FASN" in MCE Product Catalog:
Cat. No.: HY-155282
CAS No.: 3032387-88-2
Target:
Domaines de recherche:
FASN-IN-6 (compound 44) is a potent fatty acid biosynthesis (FAB) inhibitor. FASN-IN-6 is an antibacterial agent with MICs of 1 μg/mL and 4 μg/mL for S. aureus ATCC 25923 and E. faecalis ATCC 29212, respectively .
Cat. No.: HY-RS04754
Domaines de recherche:
Fasn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fasn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-110354R
CAS No.: 1094451-90-7
Synonyms: G28UCM (Standard)
Domaines de recherche:
UCM05 (Standard) is the analytical standard of Lysipressin. This product is intended for research and analytical applications. UCM05 (G28UCM) is a fatty acid synthase (FASN) and filamentous temperature-sensitive protein Z (Ftsz) inhibitor. UCM05 inhibits fatty acid synthesis, viral replication, and Gram-positive bacterial growth. UCM05 binds to FtsZ GTP-binding sites, inhibits GTPase activity, and disrupts Z-ring localization. UCM05 can be used for the research of HSV-1/2 infection, HIV-1 infection, and Gram-positive bacterial infections [1][2][3].
Cat. No.: HY-181801
Domaines de recherche:
FASN-IN-8 is a fatty acid synthase (FASN) inhibitor. FASN-IN-8 inhibits FASN-mediated de novo lipogenesis. FASN-IN-8 blocks PI3K/AKT pathway activation, inhibits cancer cells proliferation, migration and invasion. FASN-IN-8 induces apoptosis and ROS production. FASN-IN-8 can be used for the research of hepatocellular carcinoma .
Cat. No.: HY-112522
CAS No.: 2138838-56-7
Target:
Domaines de recherche:
HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.
Cat. No.: HY-112522A
CAS No.: 2138838-57-8
Target:
Domaines de recherche:
HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.
Cat. No.: HY-158649
CAS No.: 2187367-11-7
Target:
Domaines de recherche:
Fasnall benzenesulfonate is the benzenesulfonate salt form of Fasnall (HY-121250). Fasnall benzenesulfonate is the inhibitor for fatty acid synthase (FASN) with IC50 of 3.7 μM. Fasnall benzenesulfonate inhibits the proliferation and induces apoptosis in breast cancer cells. Fasnall benzenesulfonate exhibits antitumor efficacy in mice .
Cat. No.: HY-12364R
CAS No.: 218137-86-1
Domaines de recherche:
C75 (Standard) is the analytical standard of C75. This product is intended for research and analytical applications. C75 is a synthetic fatty-acid synthase (FASN) inhibitor; inhibits prostate cancer cells PC3 with an IC50 of 35 μM . C75 is a potent CPT1A activator .
Cat. No.: HY-149540
Target:
Domaines de recherche:
CTL-06 is an inhibitor of Fatty Acid Synthase (FASN) (IC50: 3 μM) and can induce apoptosis. CTL-12 blocks the cell cycle in the Sub-G1/S phase, upregulates the expression of caspase-9 and the apoptosis marker Bax, and downregulates the anti-apoptotic marker Bcl-xL. CTL-12 inhibits de novo lipogenesis, blocks the metabolic demands of tumor cells, and is commonly used in breast and colorectal cancer research .
Cat. No.: HY-149541
Target:
Domaines de recherche:
CTL-12 is an inhibitor of fatty acid synthase (FASN) (IC50: 2.5 μM) and can induce apoptosis. CTL-12 blocks the cell cycle in the Sub-G1/S phase, upregulates the expression of caspase-9 and the apoptosis marker Bax, and downregulates the anti-apoptotic marker Bcl-xL. CTL-12 inhibits de novo lipogenesis, blocks the metabolic demands of tumor cells, and is commonly used in breast and colorectal cancer research .
Target:
Cat. No.: HY-15957
CAS No.: 1579514-16-1
Target:
Domaines de recherche:
FASN-IN-7 is a potent and orally active inhibitor of human Fatty Acid Synthase (FASN). FASN-IN-7 shows enzyme inhibition on full length FASN and the FASN KR domain with IC50 values of 28 and 54 nM. FASN-IN-7 effectively inhibits proliferation of multiple cancer cell types. FASN-IN-7 increases malonyl-CoA levels and decreases palmitate levels in tumor tissues .
Cat. No.: HY-P701881
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FASN; 3-Oxoacyl-[Acyl-Carrier-Protein] Reductase; Fatty Acid Synthase; 3-Oxoacyl-[Acyl-Carrier-Protein] Synthase; FAS; Enoyl-[Acyl-Carrier-Protein] Reductase; SDR27X1; Acyl-[Acyl-Carrier-Protein] Hydrolase; Short Chain Dehydrogenase/Reductase Family 27X,
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701882
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FASN; 3-Oxoacyl-[Acyl-Carrier-Protein] Reductase; Fatty Acid Synthase; 3-Oxoacyl-[Acyl-Carrier-Protein] Synthase; FAS; Enoyl-[Acyl-Carrier-Protein] Reductase; SDR27X1; Acyl-[Acyl-Carrier-Protein] Hydrolase; Short Chain Dehydrogenase/Reductase Family 27X,
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-112829R
CAS No.: 1399177-37-7
Synonyms: TVB-2640 (Standard); FASN-IN-2 (Standard); ASC-40 (Standard)
Domaines de recherche:
Denifanstat (Standard) is the analytical standard of Denifanstat (HY-112829). This product is intended for research and analytical applications. Denifanstat (TVB-2640) is an orally active and potent Fatty Acid Synthase (FASN) inhibitor with an IC50 of 0.052 μM and an EC50 of 0.072 μM. Denifanstat has the potential for fatty liver disease and cancer research .
Cat. No.: HY-P704038
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FASN; 3-Oxoacyl-[Acyl-Carrier-Protein] Reductase; Fatty Acid Synthase; 3-Oxoacyl-[Acyl-Carrier-Protein] Synthase; FAS; Enoyl-[Acyl-Carrier-Protein] Reductase; SDR27X1; Acyl-[Acyl-Carrier-Protein] Hydrolase; Short Chain Dehydrogenase/Reductase Family 27X,
Species:
Human
Source:
E. coli
Cat. No.: HY-160126
CAS No.: 2154373-60-9
27-Norcholestenoic acid is an inverse agonist of LXRβ and LXRα that decreases basal luciferase activity and inhibits agonist-induced transactivation. 27-Norcholestenoic acid induces conformational changes in the AF-2 domain that favor corepressor over coactivator recruitment, thereby destabilizing the active receptor conformation. 27-Norcholestenoic acid downregulates FASN and SREBP-1a/c gene expression .
Cat. No.: HY-189199
CAS No.: 3093981-26-8
Domaines de recherche:
SARS-CoV-2-IN-124 is an antiviral compound. SARS-CoV-2-IN-124 directly binds to NCOA1 and promotes its lysosome-dependent degradation. SARS-CoV-2-IN-124 downregulates the expression of lipogenic enzymes FASN and SCD1. SARS-CoV-2-IN-124 inhibits SARS-CoV-2 replication in multiple cell lines. SARS-CoV-2-IN-124 can be used for research related to SARS-CoV-2 infection .
Cat. No.: HY-N21699
CAS No.: 1927024-53-0
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
