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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
119 Results for "
MST
" in MedChemExpress (MCE) Product Catalog:
Products (119)
119 Results for "MST" in MCE Product Catalog:
Cat. No.: HY-136602
CAS No.: 186379-49-7
MT-21 is an Apoptosis inducer and adenine nucleotide translocase inhibitor. MT-21 induces Apoptosis by activating JNK via the Krs/MST protein. MT-21 activates caspase-3 via caspase-9. MT-21 induces the release of cytochrome c. MT-21 can be used in the research of tumors .
Cat. No.: HY-174842
CAS No.: 696643-14-8
Research Areas:
HTS05585 (Compound Hit-1) is a selective macrophage migration inhibitory factor (MIF) inhibitor with a Kd value of 0.29 μM measured by microscale thermophoresis (MST) and 0.32±0.01 μM verified by isothermal titration calorimetry (ITC). HTS05585 inhibits the release of pro-inflammatory factors (TNF-α, IL-6, IL-1β) from LPS-induced macrophages. HTS05585 is promising for research of inflammation-related diseases such as sepsis .
Cat. No.: HY-RS24769
Target:
Research Areas:
Mst1r Rat Pre-designed siRNA Set A contains three designed siRNAs for Mst1r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-16457
CAS No.: 791635-59-1
Synonyms: MST 997
Target:
Research Areas:
Simotaxel (MST 997) is an orally active derivative of the taxane class. Simotaxel binds to β-tubulin and promotes tubulin polymerization (EC₅₀ = 0.9 μM), inhibits tubulin depolymerization, and causes cell cycle arrest at the G₂-M phase. Simotaxel disrupts the formation of the mitotic spindle and triggers the caspase-dependent apoptotic pathway (apoptosis). Simotaxel has inhibitory effects on Paclitaxel (HY-B0015) sensitive cell lines and overcomes drug resistance. Simotaxel can be used to study Paclitaxel / Docetaxel (HY-B0011) resistant solid tumors .
Cat. No.: HY-P705606
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K10; MEKK10; Prev. MLK2; Protein Kinase MST; MST; MKN28 Kinase; Mixed Lineage Kinase 2; Mitogen-Activated Protein Kinase Kinase Kinase 10; MKN28 Derived Nonreceptor_type Serine/Threonine Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706067
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K10; MEKK10; Prev. MLK2; Protein Kinase MST; MST; MKN28 Kinase; Mixed Lineage Kinase 2; Mitogen-Activated Protein Kinase Kinase Kinase 10; MKN28 Derived Nonreceptor_type Serine/Threonine Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-RS16320
Target:
Research Areas:
TAM Human Pre-designed siRNA Set A contains three designed siRNAs for TAM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27288
Target:
Research Areas:
Mpst Rat Pre-designed siRNA Set A contains three designed siRNAs for Mpst gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N20641
CAS No.: 3059457-35-8
Category:
Cat. No.: HY-100526R
CAS No.: 2061980-01-4
Target:
Research Areas:
XMU-MP-1 (Standard) is the analytical standard of XMU-MP-1 (HY-100526). This product is intended for research and analytical applications. XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50s of 71.1 and 38.1 nM, respectively .
Cat. No.: HY-172745
CAS No.: 3053775-15-5
Category:
Target:
Cat. No.: HY-114804
CAS No.: 353781-42-7
Target:
Research Areas:
BRD2577 is a selective mercaptopyruvate sulfurtransferase (3-MST) inhibitor with an IC50 of 9.9 μM. BRD2577 inhibits H2S production in colon carcinoma cells. BRD2577 exhibits weak to no significant inhibitory effect on colon cancer cell proliferation and mitochondrial activity. BRD2577 can be used for the research of colon cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
