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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
126 Results for "
PNP
" in MedChemExpress (MCE) Product Catalog:
Products (126)
126 Results for "PNP" in MCE Product Catalog:
Cat. No.: HY-173161
CAS No.: 1350456-68-6
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Mc-d-Val-d-Cit-PAB-PNP is a cleavable ADC linker that can be used for synthesizing antibody-drug conjugates (ADCs) .
Cat. No.: HY-W015996
CAS No.: 23646-68-6
Synonyms: PNP-GalNAc
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Fmoc-Asn-Pro-Val-PABC-PNP (compound 6) is a potent ADC Linker .
Cat. No.: HY-151740
CAS No.: 1956294-76-0
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4-Pentynoyl-Val-Ala-PAB-PNP is a cleavable ADC linker, that has been used to synthesis cryptophycin conjugates . 4-Pentynoyl-Val-Ala-PAB-PNP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-136108
CAS No.: 2647914-16-5
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Fmoc-Gly3-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-134354
CAS No.: 939028-75-8
Synonyms: ADP-ribose-PNP
Research Areas:
pNP-ADPr is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays. pNP-ADPr can be used for the research of poly(ADP-ribose)polymerase (PARP) enzymes .
Cat. No.: HY-129361
CAS No.: 1834516-06-1
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Fmoc-Ala-Ala-Asn-PABC-PNP is a peptide-based linker intermediate composed of Fmoc-protected Ala-Ala-Asn, PABC, and PNP. Fmoc-Ala-Ala-Asn-PABC-PNP can be used to prepare Auristatin antibody-drug conjugates (ADCs). Fmoc-Ala-Ala-Asn-PABC-PNP is applicable to tumor-related research .
Cat. No.: HY-20336G
CAS No.: 159857-81-5
Cat. No.: HY-153486
CAS No.: 2285374-43-6
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N3‑VC‑PAB‑PNP is a click chemistry intermediate containing an azide group. N3-VC-PAB-PNP serves as a linker for Bicycle STING conjugates (BSCs). N3‑VC‑PAB‑PNP is applicable in immunity and cancer-related research .
Cat. No.: HY-147021
CAS No.: 1350456-66-4
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MC-Val-D-Cit-PAB-PNP is a peptide linker that can be used for the synthesis of Antibody-Drug Conjugates (ADCs). MC-Val-D-Cit-PAB-PNP can be used to construct antibody-drug conjugates loaded with ATR/CHK1 inhibitors .
Cat. No.: HY-158199
CAS No.: 2126749-95-7
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BCN-HS-PEG2-bis(PNP) is a p-nitrophenyl ADC linker that can be used for further coupling of ADC toxins with peptide linkers. BCN-HS-PEG2-bis(PNP) can be combined with vc-PABC-MMAE (HY-15162) to form drug-linker conjugates for ADCs.
Cat. No.: HY-136100
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TCO-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). TCO-PEG1-Val-Cit-PABC-PNP is a click chemistry reagent, which contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups .
Cat. No.: HY-W145534
CAS No.: 125455-64-3
Cat. No.: HY-136100A
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TCO-PEG1-Val-Cit-PABC-PNP TFA is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). TCO-PEG1-Val-Cit-PABC-PNP TFA is a click chemistry reagent, which contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups .
Cat. No.: HY-136105
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Azido-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG1-Val-Cit-PABC-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-W145622
CAS No.: 754954-71-7
Synonyms: Gal beta(1-3)[Neu5Ac alpha(2-6)]GlcNAc-beta-PNP
Cat. No.: HY-106934
CAS No.: 133432-71-0
Synonyms: BCX 34
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Peldesine (BCX 34) is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research .
Cat. No.: HY-172291
CAS No.: 1964490-09-2
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Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker. Mal-amide-PEG8-Val-Cit-PAB-PNP consists of maleimide, a PEG spacer, Val-Cit dipeptide, PAB and PNP carbonate, and is applicable for the synthesis of ADCs.
Cat. No.: HY-W591336
CAS No.: 1884578-27-1
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Alloc-Val-Ala-PAB-PNP is a cleavable ADC linker.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
