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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
165 Results for "
choline
" in MedChemExpress (MCE) Product Catalog:
Products (165)
165 Results for "choline" in MCE Product Catalog:
Target:
Research Areas:
Choline oxidase (EC 1.1.3.17) catalyzes the oxidation of choline to glycine betaine via betaine aldehyde in glycine betaine biosynthesis and betaine acts as an osmolyte. Choline oxidase has potential in enzymatic betaine production .
Cat. No.: HY-W039760
CAS No.: 17773-10-3
Cat. No.: HY-W127656
CAS No.: 1927-06-6
Cat. No.: HY-17552R
CAS No.: 28319-77-9
Synonyms: choline Alfoscerate (Standard); Alpha-GPC (Standard); L-α-GPC (Standard)
Cat. No.: HY-16934
CAS No.: 1649450-12-3
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ML352 is a noncompetitive inhibitor of the presynaptic choline transporter (CHT) with Ki
values of 92 and 166 nM for HEK293 cells expressing human CHT and mouse forebrain synaptosomes, respectively .
Cat. No.: HY-159904
Target:
Research Areas:
ChAT IN-1 is a selective Choline Acetyltransferase (ChAT) inhibitor. It can be used to study mechanisms related to the overexpression of non-neuronal ChAT in cancers (e.g., colorectal and lung cancers) and Alzheimer’s disease (AD) .
Cat. No.: HY-W007584
CAS No.: 7314-44-5
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2,4-Dimethoxybenzyl alcohol, an aromatic alcohol, is a substrate of glucose-methanol-choline (GMC) oxidoreductase. GMC oxidoreductase displays the characteristics of an aryl-alcohol oxidase. 2,4-Dimethoxybenzyl alcohol can be used as a drug intermediate .
Cat. No.: HY-W127640
CAS No.: 16904-96-4
Cat. No.: HY-157666
CAS No.: 71242-28-9
Synonyms: PC(13:0/13:0); DTPC
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13:0 PC (PC(13:0/13:0)), also known as ditridecanoyl phosphatidyl choline (DTPC), is a phospholipid characterized by its unique structure that includes a polar head with a positively charged quaternary amine and a negatively charged phosphate, along with two non-polar fatty acid tails.
Cat. No.: HY-101036R
CAS No.: 87-67-2
Category:
Cat. No.: HY-W338346
CAS No.: 2016-36-6
Research Areas:
Salicylate choline is an orally active derivative of Aspirin (acetylsalicylic acid) (HY-14654). Salicylate choline significantly reduces IL-1β, IL-6, TNF-α and IL-10 levels in cells. Salicylate choline enhances the anti-tumor activity of the CRM1 inhibitor Selinexor (KPT-330) (HY-17536) through inducing S-phase cell cycle arrest and impairing DNA damage repair. Salicylate choline combined with Selinexor demonstrates excellent anti-tumor efficacy in mice xenograft model harboring JeKo-1 cells. Salicylate choline can be used for the study of rheumatic diseases, inflammation and cancer .
Cat. No.: HY-B0739AR
CAS No.: 33818-15-4
Synonyms: Cytidine diphosphate-choline sodium (Standard); CDP-choline sodium (Standard); Cytidine 5'-diphosphocholine sodium (Standard)
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CGP 25454A is a selective presynaptic dopamine autoreceptor antagonist which induces the increase of dopamine and acetyl choline. CGP 25454A can be used for major depression research .
Cat. No.: HY-170805
CAS No.: 1327276-39-0
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UNC0737 is an orthosteric choline kinase inhibitor. UNC0737 is also a poor inhibitor of G9a (IC50 = 5000 nM) and GLP (IC50 > 10000 nM) in the SAHH-coupled assays .
Cat. No.: HY-W440958
CAS No.: 59403-51-9
Synonyms: PSPC; PC(16:0-18:0)
1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine is an assymetrical phospholipid containing saturated palmitic and stearic acid at the sn-1 and sn-2 position respectively. The phosphate group is attached to choline.
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β-NETA is a potent and noncompetitive choline acetyltransferase (ChA; IC50=76 μM) and cholinesterase (ChE; IC50=40 μM) inhibitor. β-NETA weakly inhibits acetylcholinesterase (AChE; IC50=1 mM) .
Cat. No.: HY-150779S
CAS No.: 2483831-84-9
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Choline hydroxide (46% in water) is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism .
Cat. No.: HY-17552S
CAS No.: 2260669-07-4
Synonyms: choline Alfoscerate-d9; Alpha-GPC-d9; L-α-GPC-d9
Cat. No.: HY-123858
CAS No.: 2002495-17-0
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VU6001221 is a blood-brain barrier permeable Choline Transporter (CHT) inhibitor (IC50 = 270 nM). VU6001221 increases the likelihood of extracellular choline elevation activating synaptic α7 nicotine ACh receptors. VU6001221 attenuates potassium-induced ACh levels in the prefrontal cortex .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
