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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
165 Results for "
choline
" in MedChemExpress (MCE) Product Catalog:
Products (165)
165 Results for "choline" in MCE Product Catalog:
Cat. No.: HY-101981S2
Purity: 99.90%
Synonyms: 5'-Uridylic acid-d11 dilithium
Target:
Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Potassium Channel Cholinesterase (ChE)
Research Areas:
Uridine 5'-monophosphate-d11 (5'- Uridylic acid-d11) dilithium is deuterium labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .
Cat. No.: HY-101981S4
Synonyms: 5'-Uridylic acid-13C9 dilithium
Target:
Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Potassium Channel Cholinesterase (ChE)
Research Areas:
Uridine 5'-monophosphate- 13C9 (5'- Uridylic acid- 13C9) dilithium is 13C-labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .
Cat. No.: HY-101981S5
Purity: 98.00%
Synonyms: 5'-Uridylic acid-15N2 dilithium
Target:
Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Potassium Channel Cholinesterase (ChE)
Research Areas:
Uridine 5'-monophosphate- 15N2 (5'- Uridylic acid- 15N2) dilithium is 15N labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .
Cat. No.: HY-108915R
CAS No.: 62637-93-8
Category:
Cat. No.: HY-154857
CAS No.: 89947-80-8
Research Areas:
1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine is a glycerophosphorylcholine, consisting of glycerol phosphate, choline and palmitic acid. It accumulates in vivo at sites of oxidative stress. 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine may be a ligand of scavenger receptors class B, while oxidized phospholipids oxPC(CD36) are potent ligands of scavenger receptors class B (CD36 and SR-BI). Oxidized phospholipids (oxPLs) also play an important role in tumor apoptosis, may be elevated in malignant biliary strictures .
Cat. No.: HY-W013175S2
Synonyms: 5'-Uridylic acid-13C9,15N2 disodium
Cat. No.: HY-W197533
CAS No.: 65474-79-5
Target:
Research Areas:
3-Hydroxymethyl-β-carboline is a Benzodiazepine antagonist with a Ki value of ~1470 nM. 3-Hydroxymethyl-β-carboline reverses Flurazepam-induced sleep, cerebrovascular and cerebral metabolic inhibition, and also partially reverses Flurazepam-induced decreases in blood pressure and heart rate. 3-Hydroxymethyl-β-carboline disrupts the anticonvulsant and anxiolytic effects of Diazepam in male mice. 3-Hydroxymethyl-β-carboline has no effect on sodium-dependent high-affinity choline uptake in rat cortical or hippocampal synaptosomes .
Cat. No.: HY-163746
Target:
Research Areas:
BuChE-IN-11 (Compound 3b-1) is an selective BuChE inhibitor with an IC50 of 0.44 μM for hBuChE. BuChE-IN-11 has high blood-brain barrier permeability and exhibits strong antioxidant activity due to its free radical scavenging properties. BuChE-IN-11 interacts with the choline binding site, acetyl binding site, and peripheral anionic site, exhibiting submicromolar BuChE inhibitory activity and preventing β-amyloid (Aβ) self-aggregation. BuChE-IN-11 holds promise for research in the field of Alzheimer's disease .
Cat. No.: HY-N4119
CAS No.: 13241-32-2
Cat. No.: HY-101981S3
CAS No.: 2483830-55-1
Synonyms: 5'-Uridylic acid-13C9,15N2 dilithium
Target:
Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Potassium Channel Cholinesterase (ChE)
Research Areas:
Uridine 5'-monophosphate- 13C9, 15N2 (5'- Uridylic acid- 13C9, 15N2) dilithium is 13C and 15N-labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .
Cat. No.: HY-172236
CAS No.: 1020634-41-6
Synonyms: BNC210; IW-2143
Target:
Research Areas:
Soclenicant (BNC210) is an orally active α7 nAChR negative alteration modulator (NAM) with no apparent side effects. Soclenicant exhibits acute anxiolytic activity in rodent models of anxiety. Soclenicant inhibits rat and human α7 nAChR currents (in stably transfected cell lines) induced by acetylcholine, nicotine, choline, and the a7-specific agonist PNU-282987 (HY-12560A) with IC50 values in the range of 1.2 to 3 μM. Soclenicant can be used in studies of anxiety, trauma, and stressor-related disorders .
Cat. No.: HY-101981S1
Synonyms: 5'-Uridylic acid-15N2,d11 dilithium
Target:
Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Potassium Channel Cholinesterase (ChE)
Research Areas:
Uridine 5'-monophosphate- 15N2,d11 (5'- Uridylic acid- 15N2,d11) dilithium is deuterium and 15N labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .
Cat. No.: HY-141617S1
Cat. No.: HY-P704165
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PLD6; Protein Zucchini Homolog; Phospholipase D Family Member 6; choline Phosphatase 6; Zuc; Phospholipase D6; Phosphatidylcholine-Hydrolyzing Phospholipase D6; MitoPLD; Mitochondrial Cardiolipin Hydrolase; Phospholipase D Family, Member 6; Mitochondrial
Species:
Human
Source:
E. coli
Cat. No.: HY-P7690
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BCHE; Pseudocholinesterase; Prev. CHE1; cholinesterase 1; Prev. CHE2; cholinesterase; E1; Butyrylcholinesterase, Isoform CRA_a; Acylcholine Acylhydrolase; Carboxylic Ester Hydrolase; cholinesterase (Serum) 2; BCHE Protein; Butyrylcholine Esterase; BCHED; Butyrylcholinesterase; choline Esterase II
Species:
Human
Source:
HEK293
Cat. No.: HY-N4119R
CAS No.: 13241-32-2
Cat. No.: HY-N8376
CAS No.: 20725-03-5
Synonyms: (±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone
Category:
Flavanonols Flavonoids Anacardiaceae Extract Phenols Polyphenols Plants Toxicodendron vernicifluum (Stokes) F. A. Barkl.
Target:
Synonyms: SAN 9789
Research Areas:
Norflurazon (SAN 9789) is a pre-emergence Herbicide. Norflurazon non-competitively inhibits phytoene desaturase by competing with the enzyme cofactor and disrupts carotenoid biosynthesis, thereby leading to chlorophyll photodegradation and chlorosis. Norflurazon inhibits MGDG synthase, CDP-choline phosphotransferase, Omega-3 FAD7 desaturase, and PG delta-3-trans desaturase, and activates LysoPC-acyltransferase and Omega-3 FAD3 desaturase. Norflurazon inhibits photosynthetic membrane organization, mitochondrial respiration, ATP production, PI3K signaling, and ERK1/2 phosphorylation. Norflurazon activates MAPK P38 phosphorylation and ER stress signaling. Norflurazon induces morphological malformations and cardiovascular effects in zebrafish embryos .
Cat. No.: HY-W319295
CAS No.: 3637-10-3
Target:
Research Areas:
TEMPOL-H is the reduced hydroxylamine form of the stable nitroxide radical Tempol (HY-100561), and serves as the active metabolite of OT-551 (HY-W556870). TEMPOL-H acts as a potent antioxidant and free radical scavenger. TEMPOL-H protects retinal pigment epithelial cells from acute light-induced damage, and protects mice from lethal whole-body radiation. TEMPOL-H inhibits lens opacification in mice, prevents glutathione loss in rat lenses under stress, blocks protein leakage in rhesus monkey lenses under stress, and maintains the 3H-choline accumulation capacity of the lens. TEMPOL-H can be used in studies related to light-induced retinal pigment epithelial degeneration and age-related cataract .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
