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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1990 Results for "
of
" in MedChemExpress (MCE) Product Catalog:
Products (1990)
1990 Results for "of" in MCE Product Catalog:
3
3 Cited Publications
Research Areas:
Mitoquinol is an orally active mitochondria-targeted antioxidant. Mitoquinol can regulate mitochondrial respiration and oxidation. Mitoquinol inhibits ROS production, and improves phagocytosis and glycolysis in ethanol-exposed macrophages via the HIF-1α-PFKP axis. Additionally, Mitoquinol can partially alleviate heat stress-induced decreases in growth performance, inflammatory responses, and metabolic disorders in pigs .
3
3 Cited Publications
Cat. No.: HY-N1401
CAS No.: 112246-15-8
3
Target:
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P74264
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD81; CD81 Antigen (Target of Antiproliferative Antibody 1); Prev. TAPA1; Tspan-28; TSPAN28; TAPA-1; Tetraspanin-28; Target of The Antiproliferative Antibody 1; CD81 Antigen; Tetraspanin; S5.7; CVID6; CD81 Molecule; 26 KDa Cell Surface Protein TAPA-1
Species:
Human
Source:
HEK293
3
3 Cited Publications
Cat. No.: HY-W013935
CAS No.: 77-40-7
3
3 Cited Publications
Cat. No.: HY-P80231
Synonyms: FRAP, FRAP1, FRAP2, RAFT1, RAPT1, MTOR, Serine/threonine-protein kinase mTOR, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1, Tyrosine-protein kinase mTOR, mTOR
3
3
3 Cited Publications
Cat. No.: HY-P7232
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LEP; Leptin (Murine Obesity Homolog); Prev. OBS; Obese Protein; Prev. OB; Obese, Mouse, Homolog of; Obesity Factor; LEPD; Leptin; Leptin (Obesity Homolog, Mouse)
Species:
Human
Source:
E. coli
3
3
3 Cited Publications
Synonyms: Methylprednisolone hydrogen succinate sodium
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Methylprednisolone succinate (Methylprednisolone hydrogen succinate) sodium is a prodrug of Methylprednisolone (HY-B0260) and glucocorticoid with immunosuppressant and anti-inflammatory activity. Methylprednisolone succinate sodium binds cytosolic glucocorticoid receptors, translocates to nuclei, and modulates target gene transcription. Methylprednisolone succinate sodium alters Bax, Bcl-2, occludin, and ZO-1 expression; attenuates TLR4/NF-κB signaling; suppresses proinflammatory cytokine production and immune cell activation. Methylprednisolone succinate sodium can be used for the research of intracranial haemorrhage, rheumatoid arthritis, multiple sclerosis, preterminal cancer, inflammatory conditions, shock, immediate-type hypersensitivity, acute myocardial ischemia, hypoxic heart muscle damage, and traumatic spinal cord injury .
3
3 Cited Publications
Synonyms: Methylprednisolone hydrogen succinate
Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Methylprednisolone succinate (Methylprednisolone hydrogen succinate) is a prodrug of Methylprednisolone (HY-B0260) and glucocorticoid with immunosuppressant and anti-inflammatory activity. Methylprednisolone succinate binds cytosolic glucocorticoid receptors, translocates to nuclei, and modulates target gene transcription. Methylprednisolone succinate alters Bax, Bcl-2, occludin, and ZO-1 expression; attenuates TLR4/NF-κB signaling; suppresses proinflammatory cytokine production and immune cell activation. Methylprednisolone succinate can be used for the research of intracranial haemorrhage, rheumatoid arthritis, multiple sclerosis, preterminal cancer, inflammatory conditions, shock, immediate-type hypersensitivity, acute myocardial ischemia, hypoxic heart muscle damage, and traumatic spinal cord injury .
3
Research Areas:
Ezurpimtrostat (GNS561) is an orally active PPT1 inhibitor, autophagy inhibitor, immunomodulator, anti-inflammatory agent, and anticancer agent. Ezurpimtrostat inhibits PPT1, dysregulates lysosomal function, redistributes mTOR, and induces apoptosis. Ezurpimtrostat reduces IFN‑α, CRP, immune complex deposition, and SARS‑CoV‑2 viral load. Ezurpimtrostat can be used for the study of systemic lupus erythematosus, SARS‑CoV‑2, hepatocellular carcinoma, fibrosis, and related disorders .
3
3 Cited Publications
Cat. No.: HY-P80324
Synonyms: Drosophila, homolog of, MADR2 antibody;
hMAD-2 antibody;
JV181 antibody;
MAD antibody;
MAD homolog 2 antibody;
MADH2 antibody;
MADR2 antibody;
MGC22139 antibody;
SMAD 2 antibody;
SMAD family member 2 antibody;
SMAD2 antibody
3
3 Cited Publications
Synonyms: Bisperoxovanadium(phen) trihydrate
Target:
Research Areas:
BpV(phen) trihydrate, a insulin-mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-β and PTP-1B, respectively. BpV(phen) trihydrate inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) trihydrate strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFNγ). BpV(phen) trihydrate can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity .
3
3 Cited Publications
Cat. No.: HY-P7309
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor Necrosis Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer of Apoptosis; APO3L; Tumor Necrosis Factor Ligand 4A; Tumor Necrosis Factor Ligand Superfamily Member 12; HCG1991317, Is
Species:
Human
Source:
CHO
3
3 Cited Publications
Cat. No.: HY-P73681
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RELA; NF-Kappa-B Transcription Factor P65; Prev. NFKB3; P65 Iso5 Isoform Delta 10; Nuclear Factor of Kappa Light Polypeptide Gene Enhancer In B-Cells 3; Alternative Protein RELA; P65; NF-Kappa-B P65delta3; V-Rel Avian Reticuloendotheliosis Viral Oncogene
Species:
Human
Source:
E. coli
2
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P70577
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component of Amyloid Precursor; Prev. PARK4; Non A-Beta Component of AD Amyloid; Alpha-Synuclein; Non-A Beta Component of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuclein; Synuclein, Alpha (Non A4 Component of Amyloid Precursor); Α-Synuclein; Synuclein Alpha; Non A4 Component of Amyloid Precursor
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P71335
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: STAT1; Signal Transducer And Activator of Transcription 1, 91kD; Signal Transducer And Activator of Transcription 1; Signal Transducer And Activator of Transcription; Transcription Factor ISGF-3 Components P91/P84; CANDF7; STAT91; IMD31A; ISGF-3; IMD31B; Signal Transducer And Activator of Transcription 1-Alpha/Beta; IMD31C; Signal Transducer And Activator of Transcription 1, 91kDa
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P73628
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: STAT1; Signal Transducer And Activator of Transcription 1, 91kD; Signal Transducer And Activator of Transcription 1; Signal Transducer And Activator of Transcription; Transcription Factor ISGF-3 Components P91/P84; CANDF7; STAT91; IMD31A; ISGF-3; IMD31B; Signal Transducer And Activator of Transcription 1-Alpha/Beta; IMD31C; Signal Transducer And Activator of Transcription 1, 91kDa
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
