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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
542 Results for "
protein functionalization
" in MedChemExpress (MCE) Product Catalog:
Products (542)
542 Results for "protein functionalization" in MCE Product Catalog:
Cat. No.: HY-D1320
CAS No.: 1267539-32-1
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Cyanine5 azide chloride is a Fluorescent probe for cell-selective bacterial protein labeling, as well as a fluorescent dye for single-molecule imaging and dynamic tracking of intracellular organelles. Cyanine5 azide chloride can conjugate with the alkynyl side chain of propargylglycine incorporated into bacterial proteins by the engineered methionyl-tRNA synthetase variant PraRS via copper (I)-catalyzed azide-alkyne [3+2] cycloaddition reaction, thereby enabling in-gel fluorescent visualization of labeled proteins. Cyanine5 azide chloride can diffuse across cell membranes and undergo copper-free click reaction with DBCO-functionalized scAVD pre-bound to DBCO-functionalized biotin, forming fluorescent nanoprobes with enhanced brightness, photostability and localization accuracy, and exhibiting discrete photobleaching steps. The excitation wavelength of Cyanine5 azide chloride is Ex = 633 nm .
Cat. No.: HY-140648
Purity: ≥95.0%
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Amine-PEG5000-amine is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. Amine-PEG5000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
Cat. No.: HY-D2910
CAS No.: 2089058-15-9
Cat. No.: HY-163167
CAS No.: 2821804-11-7
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VH 032 amide-alkylC5-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand .
Cat. No.: HY-140654
Purity: ≥90.0%
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Biotin-PEG2000-amine is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. Biotin-PEG2000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
Cat. No.: HY-137098
CAS No.: 1656990-68-9
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VH032-C7-COOH is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. VH032-C7-COOH contains an E3 ligase ligand and an alkyl linker with a terminal amine for conjugation of target protein ligands .
Cat. No.: HY-157566
CAS No.: 2520105-60-4
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Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride is a functionalized cerebellar ligand for PROTAC development, combining E3 ligand and terminal piperidine for subsequent chemical reactions. A protein degradant with a rigid connector is generated .
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Triallyl pentaerythritol (PEATA), a crosslinker, decreases the protein rejection compared to membranes functionalized with MBAA or without any crosslinker .
Cat. No.: HY-174967C
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3,5-Difluoro-L-tyrosine is a functional, tyrosinase-resistant mimetic of tyrosine. 3,5-Difluoro-L-tyrosine can be used to analyze the substrate specificity of protein tyrosine phosphatases (PTPs) .
Cat. No.: HY-131866
CAS No.: 2172819-72-4
Synonyms: VH 032 amide-alkylC2-acid
Research Areas:
(S,R,S)-CO-C2-acid (VH 032 amide-alkylC2-acid) is a functionalized von-Hippel-Lindau (VHL) protein ligand and linker conjugate, which can be used in the research and development of PROTACs .
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MNG-14a is an amphiphilic compound that can be used to aid the isolation of membrane proteins, and functional and structural determination of membrane proteins .
Cat. No.: HY-177649
CAS No.: 3053113-45-1
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Nivudirsen is an antisense oligonucleotide that can promote the synthesis of functional dystrophin protein.
Cat. No.: HY-W283166
CAS No.: 253678-67-0
Cat. No.: HY-158615
CAS No.: 2706536-26-5
Synonyms: Stimulator of interferon genes 18
STING18 (Stimulator of interferon genes 18) is a compound that inhibits STING protein by utilizing a small molecule active site dimer, with good oral exposure, slow binding kinetics, and functional inhibitory activity on STING-mediated cytokine release.
Cat. No.: HY-W095635
CAS No.: 17787-40-5
Cat. No.: HY-P4275
CAS No.: 20238-94-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
