391 Results for "

P1

" in MedChemExpress (MCE) Product Catalog:
Products (391)

391 Results for "P1" in MCE Product Catalog:

Cat. No.: HY-N15117A
Target:  

Antibiotic Bacterial

Domaines de recherche:  

Infection

Polymyxin P1 TFA is a lipopeptide antibiotic belonging to the Polymyxin family, and it is a secondary metabolite produced by the rhizosphere bacterium Paenibacillus polymyxa M-1. Polymyxin P1 TFA binds to bacterial outer membrane lipopolysaccharides, permeabilizes cell membranes, and induces dense protrusions on the cell surface of phytopathogenic Erwinia strains. Polymyxin P1 TFA inhibits the growth of phytopathogenic Erwinia amylovora and E. carotovora. Polymyxin P1 TFA can be used for the research of fire blight and soft rot [1].
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Cat. No.: HY-13634
CAS No.: 286942-97-0
Synonyms: TER199; TLK199 hydrochloride
Domaines de recherche:  

Cancer

Ezatiostat hydrochloride (TER199; TLK199 hydrochloride) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat hydrochloride leads to JNK activation by inhibiting GSTP1. Ezatiostat hydrochloride stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat hydrochloride has the potential for myelodysplastic syndrome (MDS) treatment [1] .
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Cat. No.: HY-P12143
Target:  

GCGR GLP Receptor

Domaines de recherche:  

Metabolic Disease

GCGR/GLP‐1 receptor agonist P1 is a dual GCGR/GLP-1R agonist. GCGR/GLP‐1 receptor agonist P1 activates human GCGR in vitro and induces the cyclic adenosine monophosphate (cAMP) signaling pathway. GCGR/GLP‐1 receptor agonist P1 is applicable to research related to type 2 diabetes and obesity [1].
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Cat. No.: HY-P11264
Cyclic peptide P1-1 is a high-potent GPR55 antagonist. Cyclic peptide P1-1 antagonizes GPR55 and suppresses collagen secretion. Cyclic peptide P1-1 reduces ROS production, attenuates ER stress, and inhibits mitochondria-associated Apoptosis. Cyclic peptide P1-1 inhibits the expression of α-SMA and COL1α. Cyclic peptide P1-1 ameliorates CCl4 (HY-Y0298)-induce and MCD-diet-induce acute liver inflammation and fibrosis [1].
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Cat. No.: HY-10955
CAS No.: 918333-06-9
Target:  

Calcium Channel

Domaines de recherche:  

Neurological Disease

TTA-P1 is a potent state-independent compound inhibiting human T-type calcium channel. T-type calcium channels play a role in diverse physiological responses including neuronal burst firing, hormone secretion, and cell growth. TTA-P1 has the potential for the research of absence epilepsy [1].
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Cat. No.: HY-P10702
CAS No.: 292605-65-3
Domaines de recherche:  

Others

SAF-p1 is a self-assembling fiber peptide that can form sticky-ended heterodimers by assembling with SAF-p2 (HY-P10703) through complementary amino acid sequences. These heterodimers further self-assemble into long-chain fiber structures. SAF-p1 is promising for the development of nanomaterials in the biomedical field [1].
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Cat. No.: HY-137602
CAS No.: 26184-65-6
Synonyms: Up2U
Target:  

P2Y Receptor

Domaines de recherche:  

Others

P1,P2-Diuridine-5’-diphosphate (Up2U) is a symmetrical dinucleoside polyphosphate containing two pyrimidine base moieties. P1,P2-Diuridine-5’-diphosphate is also an activator of purinergic P2Y receptor [1].
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Cat. No.: HY-131420
CAS No.: 2724-57-4
Synonyms: Aseanostatin P1; Isotetradecanoic acid
12-Methyltridecanoic acid is a methylated fatty acid that has been found in milk. 12-Methyltridecanoic acid (200 μM) reduces angiogenesis and corneal opacity in alkaline or Pseudomonas aeruginosa-induced ocular mouse models.
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Cat. No.: HY-131482
CAS No.: 299216-98-1
Target:  

Liposome

Domaines de recherche:  

Others

PtdIns-(3)-P1(1,2-dioctanoyl) sodium (compound 1b) is a glycogen phosphate that plays a key role in eukaryotic membrane trafficking and agonist-activated intracellular signaling [1].
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Cat. No.: HY-E70371
CAS No.: 1943614-02-5
Domaines de recherche:  

Others

Cre recombinase is a resolvase derived from the P1 bacteriophage. Cre recombinase catalyzes site-specific recombination between two loxP DNA sequences, converts dimers of P1 chromosome into monomers before cell division. Cre recombinase is utilized in genetic engineering and molecular biology applications [1].
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Cat. No.: HY-P10668
CAS No.: 410532-54-6
Target:  

Dengue Virus Flavivirus

Domaines de recherche:  

Infection

Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection [1].
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Cat. No.: HY-143610
CAS No.: 2654025-97-3
Target:  

Akt

Domaines de recherche:  

Cancer

AKT-IN-7 (compound 1-P1) is a potent AKT inhibitor. AKT-IN-7 has the potential for cancer research [1].
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Cat. No.: HY-114688
CAS No.: 62959-30-2
Domaines de recherche:  

Others

BITC-SG is the conjugate of phenylisothiocyanate (BITC) and glutathione (GSH). BITC-SG is involved in the irreversible inhibition of GST P1-1 [1] .
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Cat. No.: HY-16123
CAS No.: 439943-59-6
Domaines de recherche:  

Cancer

Canfosfamide (hydrochloride) is a prodrug that upon activation by glutathione s-transferase P1-1 (GSTP1-1) yields an anticancer alkylating agent and a glutathione derivative.
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Cat. No.: HY-151404
CAS No.: 2787593-12-6
Target:  

Apoptosis

Domaines de recherche:  

Cancer

Antitumor agent-76 (Compound TP-P1) is an orally active, rapid-release and water-soluble Triptolide (HY-32735) proagent with antitumor activity [1].
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Cat. No.: HY-D2280
CAS No.: 3057270-84-2
Estrogen receptor β/HDAC probe 1 (compound P1) is a near-infrared fluorescent probe that dual-targets the estrogen receptor (Estrogen Receptor/ERR) β/histone deacetylase HDAC [1].
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Cat. No.: HY-N7428
CAS No.: 80840-09-1
1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is an endogenous metabolite. The imprinted polymer P-1 shows affinity for 1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol [1].
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Cat. No.: HY-150691
CAS No.: 2409178-86-3
Target:  

SARS-CoV

Domaines de recherche:  

Cancer

SARS 3CLpro-IN-1 (Compound 3b) is a SARS 3CL protease inhibitor with an IC50 value of 95 μM, as a specific stereo isomer of the octahydroisochromene scaffold, directs the P1 site imidazole [1].
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Cat. No.: HY-139406
CAS No.: 1246303-11-6
Synonyms: PtdIns-(4)-P1 (1,2-dioctanoyl) ammonium; 08:0 PI(4)P ammonium
Domaines de recherche:  

Neurological Disease

1,2-Dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-4'-phosphate) (PtdIns-(4)-P1 (1,2-dioctanoyl)) ammonium is a synthetic phosphatidylinositol. 1,2-Dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-4'-phosphate) ammonium can be used for the research of signal transduction research [1].
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Cat. No.: HY-144211
CAS No.: 2755415-30-4
Target:  

SOS1 Ras

Domaines de recherche:  

Cancer

SOS1-IN-7 (compound 18-p1) is a potent SOS1 inhibitor with IC50s of 20 and 67 nM for SOS1-G12D and SOS1-G12V, respectively [1].
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