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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
90 Results for "
Treg
" in MedChemExpress (MCE) Product Catalog:
Products (90)
90 Results for "Treg" in MCE Product Catalog:
Cat. No.: HY-P4790
CAS No.: 305815-28-5
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Cat. No.: HY-B0172AS1
CAS No.: 2410277-60-8
Synonyms: 3β-Hydroxy-5α-cholanic acid-d4
Cat. No.: HY-120785A
CAS No.: 2309312-90-9
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SR1555 hydrochloride is the hydrochloride salt form of SR1555 (HY-120785). SR1555 hydrochloride is an inverse agonist for retinoic acid receptor-related orphan nuclear receptor γ (RORγ) with an IC50 of 1 μM. SR1555 hydrochloride inhibits the development and function of pro-inflammatory TH17 cell, increases the frequency of anti-inflammatory T regulatory (Treg) cells. SR1555 hydrochloride can be used for research about autoimmune diseases .
Cat. No.: HY-W713010
Cat. No.: HY-P10982
CAS No.: 2767993-73-5
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Cat. No.: HY-P990177
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Cat. No.: HY-P990206
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Cat. No.: HY-W016773S
CAS No.: 347841-78-5
Cat. No.: HY-162415
CAS No.: 2760585-35-9
CSF1R-IN-22 (Compound C19) is an orally effective CSF-1R selective inhibitor (IC50<6 nM). CSF1R-IN-22 enhances the secretion of CXCL9 from M2 macrophages, increases CD8 + T cell infiltration. CSF1R-IN-22 boosts anti-tumor immune responses of anti-PD-1, and induces apoptosis in tumor cells. CSF1R-IN-22 can effectively reprogram M2-like TAMs (tumor-associated macrophages) to the M1 phenotype and reshape the TME by inducing the recruitment of CD8 + T cells into tumors and reducing the infiltration of immunosuppressive Tregs and MDSCs .
Cat. No.: HY-P99911
CAS No.: 1635395-27-5
Synonyms: MEDI-6383
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Cat. No.: HY-P991944
Cat. No.: HY-N17465
CAS No.: 526222-27-5
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Cat. No.: HY-P991942A
Synonyms: BAY3375968 (FUT8-KO); TPP-23411 (FUT8-KO)
Lanerkitug (FUT8-KO) (BAY3375968 (FUT8-KO)) is an anti-CCR8 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Lanerkitug (HY-P991942) selectively depletes human CCR8+Tregs via antibody dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP). Lanerkitug can be used in the research of solid tumors .
Cat. No.: HY-P11014
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Cat. No.: HY-P992029
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Cat. No.: HY-P992361
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Cat. No.: HY-P992365
Cat. No.: HY-P991942
Synonyms: BAY3375968; TPP-23411
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Cat. No.: HY-P991911
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
