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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1018 Results for "
Detection
" in MedChemExpress (MCE) Product Catalog:
Products (1018)
1018 Results for "Detection" in MCE Product Catalog:
Cat. No.: HY-W800696
CAS No.: 2644752-86-1
Cat. No.: HY-137557A
Synonyms: (E/Z)-APN1607; (E/Z)-PM-PBB3
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(E/Z)-Florzolotau ((E/Z)-APN1607) is a mixed configuration or unspecified configuration of Florzolotau (HY-137557). Florzolotau (APN1607) is a positron emission tomography (PET) ligand that can be used for the detection of Alzheimer's disease (AD) and other tau proteinopathies. Its binding sites are located in the β-sheet of paired helical filaments (PHFs) and straight filaments (SFs) of tau protein, as well as in the C-shaped cavity of SFs. In addition, APN-1607 binds to intraneuronal inclusions in Alzheimer's disease (AD), primary age-related tauopathy (PART) and posterior cortical atrophy (PCA). Florzolotau shows promise for PET imaging studies of neurological disorders, particularly tau proteinopathies .
Cat. No.: HY-142117S1
CAS No.: 1309935-98-5
Cat. No.: HY-184641
Aminated magnetic microspheres are superparamagnetic magnetic particles with amino functional groups modified on their surface, widely used in biomedical and molecular biology research. This 1μm aminated magnetic microsphere is composed of polystyrene and nano-iron oxide, exhibiting hydrophilicity and good biocompatibility. The aminated magnetic microspheres possess superparamagnetism, fast magnetic response, good monodispersity, ensuring reaction uniformity and detection consistency. The unique rough surface structure and polymer modification give the aminated magnetic microspheres a high amino density, allowing them to covalently couple with bioligands such as peptides, proteins, oligonucleotides, drug molecules, and glycoproteins through the action of special chemical reagents (such as glutaraldehyde). They serve as excellent coating materials and are important carrier tools in medical and biomolecular research.
Cat. No.: HY-184777
CAS No.: 94367-34-7
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Met-AMC is a fluorescent substrate used to detect the activity of methionine aminopeptidase (MetAP). Hydrolysis of the substrate releases the fluorophore AMC, with detection performed at an excitation wavelength of 360 nm and an emission wavelength of 460 nm. Met-AMC can distinguish the effects of different metal cofactors on the substrate preference of MetAP1: Zn (II)-MetAP1 barely hydrolyzes Met-AMC, while Co (II)-, Mn (II)-, and Ni (II)-MetAP1 can stably cleave this substrate. Met-AMC can be used to establish an intracellular MetAP activity cell-based assay system, which quantifies the intracellular MetAP inhibition level by monitoring the fluorescence signal from substrate hydrolysis in living cells .
Cat. No.: HY-D1422
CAS No.: 1445108-32-6
Synonyms: BDNCA-346
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ER Tracker Yellow (BDNCA-346) is a Fluorescent probe for targeted visualization of temperature at the endoplasmic reticulum. Its detection mechanism depends on temperature, with fluorescence intensity decreasing at higher temperatures due to preferential non-radiative processes; this intensity reversibly returns to baseline when cooled, provided the probe does not precipitate or degrade. It localizes specifically to the endoplasmic reticulum, where it may covalently attach to biomacromolecules via a thiol-reactive moiety, and its fluorescence remains stable after cell fixation; its fluorescence intensity is unaffected by physiological pH ranges of 5.0–8.0 and free Ca²⁺ concentrations of 0–800 μM. Its excitation/emission wavelength is Ex/Em = 559/581 nm[1].
Cat. No.: HY-D2768
CAS No.: 467233-93-8
Cat. No.: HY-D3146
CAS No.: 1418017-91-0
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Di-4-AN (F) EPPTEA is a voltage-sensitive dye used for membrane potential imaging and optical recording of electrical activity in excitable cells and tissues. Its detection mechanism is based on electrochromism (also known as the molecular Stark effect). The single-photon excitation/emission wavelengths measured in ethanol solution are Ex/Em = 444/610 nm, and it can be excited via 1064 nm two-photon excitation in optical recording applications. Di-4-AN (F) EPPTEA can be used to record backpropagating action potentials in individual dendritic spines of brain cortical slices, map subcellular action potential characteristics of single cardiomyocytes, and perform real-time recording of multicellular action potentials in cerebellar slices .
Cat. No.: HY-DY1073
CAS No.: 1392820-50-6
Solvent and concentration: DMSO: 2 mM
Cat. No.: HY-P1576A
Cat. No.: HY-P5292A
CAS No.: 2375849-11-7
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Cat. No.: HY-P990816
Cat. No.: HY-P990849
Cat. No.: HY-P990854
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Cat. No.: HY-P990862
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Cat. No.: HY-128974R
CAS No.: 69227-93-6
Synonyms: Lauryl Maltoside (Standard)
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N-Dodecyl-β-D-maltoside (Standard) is the analytical standard of N-Dodecyl-β-D-maltoside (HY-128974). This product is intended for research and analytical applications. N-Dodecyl-β-D-maltoside (Lauryl Maltoside) is a non-ionic detergent. N-Dodecyl-β-D-maltoside has strong adsorption on alumina, titanium dioxide and hematite. N-Dodecyl-β-D-maltoside can promote the reactivation of various proteins. N-Dodecyl-β-D-maltoside can effectively stabilize photoactive reaction center complexes (RCs) and inhibit the degradation of Rhodopseudomonas spheroides R-26 reaction center in solution. N-Dodecyl-β-D-maltoside can be used for purification and stabilization of RNA polymerase and for detection of protein-lipid interactions .
Cat. No.: HY-128974S
CAS No.: 849110-74-3
Synonyms: Lauryl Maltoside-d25
Cat. No.: HY-142117S
Purity: 99.25%
Cat. No.: HY-160116
CAS No.: 1565797-17-2
Research Areas:
α-Synuclein aggregate binder 1 (Compound C05-05) is a specific binder for α-synuclein aggregates and can inhibit α-synuclein aggregation. α-Synuclein aggregate binder 1 can be used as a fluorescent probe (excitation wavelength 900 nm, detection wavelength 500-550 nm) for optical imaging, and can also inhibit α-synuclein fibril formation by blocking the aggregation process. α-Synuclein aggregate binder 1 can be used for positron emission tomography (PET) imaging after being labeled with 18F. α-Synuclein aggregate binder 1 can be used for visual diagnosis of brain lesions and mechanism research of neurodegenerative diseases such as Parkinson's disease and Lewy body dementia .
Cat. No.: HY-D0027R
CAS No.: 26093-31-2
Synonyms: Coumarin 120 (Standard); AMC (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
