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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1018 Results for "
Detection
" in MedChemExpress (MCE) Product Catalog:
Products (1018)
1018 Results for "Detection" in MCE Product Catalog:
Cat. No.: HY-P990002
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Cat. No.: HY-P990202
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Cat. No.: HY-W011654
CAS No.: 5094-33-7
Synonyms: 4-Aminophenyl-beta-D-galactopyranoside, 98%
Cat. No.: HY-W615095
CAS No.: 2227450-68-0
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Biotin-PEG2-alkyne is a click chemistry PEG linker based on copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC), as well as a biotinylation reagent. In solution-phase and click labeling systems, Biotin-PEG2-alkyne efficiently conjugates biotin groups to azide-functionalized streptavidin amplicons. Biotin-PEG2-alkyne is also widely applicable in fixed cells and mouse intestinal tissue sections to achieve specific biotinylation of various azide-labeled biomolecules (such as proteins, lipids, DNA, and Afatinib (HY-10261)), thereby effectively promoting signal amplification and precise detection of targets .
Cat. No.: HY-W750960R
CAS No.: 1377605-22-5
Biotinylated isoxazole (Standard) is the analytical standard of Biotinylated isoxazole (HY-W750960). This product is intended for research and analytical applications. Biotinylated isoxazole is a chemical probe that selectively precipitates proteins containing prion-like low-complexity domains and Cross-β prion-like polymers through recognition of Cross-β structure. Biotinylated isoxazole induces precipitation of proteins containing intrinsically disordered regions through microcrystal formation in solution. Biotinylated isoxazole enables enrichment of Amyloid oligomers for ELISA-based detection. Biotinylated isoxazole decreases Gems and increases misfolded PFN1 aggregates .
Cat. No.: HY-165399
CAS No.: 145253-48-1
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RB104 is a highly selective neutral endopeptidase (NEP) inhibitor that exhibits extremely high affinity for Aplysia californica apNEP (Kd=0.16-0.26 pM) and rat NEP (Kd=7.0-26.8 pM). RB104 effectively blocks apNEP-mediated cleavage of Leu-enkephalin and shows minimal cross-reactivity with other zinc peptidases. Furthermore, RB104 can be iodinated or radiolabeled with 125I to serve as a probe, and is widely used in inhibitor gel electrophoresis, binding assays, Western blotting, and autoradiographic tissue localization, enabling sensitive detection of nanogram-level NEP in crude extracts and tissue sections .
Cat. No.: HY-D3109
CAS No.: 148043-22-5
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pH-Ap-1 is a fluorescent probe used for ratiometric monitoring of pH fluctuations during autophagy in living cells, and it can detect intracellular pH changes in the autophagy process. For fluorescence detection of pH-Ap-1, its excitation wavelength is 475 nm, with an emission wavelength of 538 nm under alkaline conditions and 645 nm under acidic conditions. For intracellular imaging, excitation is performed at 488 nm: the emission light ranging from 500-550 nm is collected via the green channel corresponding to 538 nm, while the emission light ranging from 625-750 nm is collected via the red channel corresponding to 645 nm. pH-Ap-1 exhibits excellent photostability and chemical stability .
Cat. No.: HY-D3123
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Ac-MtFluNox is a mitochondria-targeted Fluorescent probe that can be used for the selective detection of labile Fe (II). Ac-MtFluNox can enter living cells, where intracellular esterases cleave its acetyl protecting group to generate activated MtFluNox. Ac-MtFluNox functions through an Fe (II)-mediated deoxygenation mechanism of its amine N-oxide group, which eliminates the fluorescence quenching effect and oxidizes Fe (II) to Fe (III) to deplete the catalytically active Fe (II) pool. A FITC filter set (excitation 465-500 nm, emission 516-556 nm) is used for live-cell imaging. Ac-MtFluNox can be applied to studies related to myocardial ferroptosis .
Cat. No.: HY-D3126
CAS No.: 2420449-92-7
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IOPBA is a fluorescent probe that can be used for the detection and bioimaging of trivalent iron ions Fe 3+ and fluoride ions F - in living cells. IOPBA emits blue fluorescence in its native state, but upon the introduction of Fe 3+, it forms a Fe 3+-IOPBA π-complex, where Fe 3+ ions coordinate with two phenyl groups of IOPBA, resulting in fluorescence quenching. IOPBA returns to its free state and recovers its original fluorescence after F - sequesters Fe 3+ to form the more stable [FeF6] 3- and dissociates the Fe 3+-IOPBA complex. The excitation wavelength of IOPBA is 342 nm, and its emission wavelength is 458 nm .
Cat. No.: HY-D3520
CAS No.: 2484683-99-8
Cat. No.: HY-D3602
CAS No.: 2558211-88-2
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Mito-CS1 is a fluorescent probe for imaging and reversible detection of the exchangeable mitochondrial Cu + pool in living cells. Mito-CS1 combines a Cu +-responsive fluorescent platform with a mitochondria-targeted triphenylphosphonium group, which localizes the probe to mitochondria via a proton gradient. Mito-CS1 contains a thioether-rich receptor for the selective recognition and binding of Cu +, triggering a fluorescence turn-on response by inhibiting photoinduced electron transfer. The apo-form of Mito-CS1 has excitation/emission wavelengths of 555/569 nm, while those of Mito-CS1 after binding to Cu + are 550/558 nm .
Cat. No.: HY-DY1006
CAS No.: 25535-16-4
Solvent and Concentration: Sterile water: 1 mg/mL
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
Cat. No.: HY-E71730
Synonyms: RNA m1G Demethylase (D135S)
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AlkB (D135S), Nuclease-free (RNA m1G Demethylase (D135S)) is a nuclease-free N1-methylguanosine (m1G) demethylase that specifically removes the methyl group from m1G residues in small non-coding RNAs. AlkB (D135S), Nuclease-free effectively promotes the reverse transcription of small non-coding RNAs and supports high-throughput sequencing methods such as CPA-seq. AlkB (D135S), Nuclease-free can be used for the precise detection and quantitative analysis of methylated small non-coding RNAs that are easily missed by conventional methods .
Cat. No.: HY-P11933
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FAHF is a polypeptide-based dual-signal fluorescent colorimetric probe synthesized by conjugating the 5-carboxyfluorescein (5-FAM) (HY-66022) fluorophore to the Ala-His-Phe-NH2 tripeptide backbone. FAHF achieves highly selective recognition of Cu 2+ via fluorescence quenching and colorimetric change. The FAHF-Cu 2+ complex responds to Glyphosate (HY-B0863) based on the displacement effect, resulting in fluorescence enhancement and a visually distinguishable color change. FAHF can penetrate cell membranes to enable cascade detection of copper (II) and glyphosate in living cells, and it can also be combined with smartphone RGB analysis for semi-quantitative identification .
Cat. No.: HY-P1576
CAS No.: 163560-19-8
Cat. No.: HY-P5292
CAS No.: 2192215-74-8
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Cat. No.: HY-W016352
CAS No.: 96-97-9
Synonyms: Anilotic acid, 99%
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2-Hydroxy-5-nitrobenzoic acid, 99% (Anilotic acid, 99%) is a basic chemical raw material and organic synthesis intermediate that can be used to synthesize Mesalamine (HY-15027). 2-Hydroxy-5-nitrobenzoic acid, 99% is a matrix for ultraviolet matrix-assisted laser desorption/ionization (UV-MALDI) mass spectrometry. 2-Hydroxy-5-nitrobenzoic acid, 99% can also serve as an HPLC analytical standard, pH indicator, and heavy metal detection agent. 2-Hydroxy-5-nitrobenzoic acid, 99% can also be used to study the oxidation of phenolic compounds .
Cat. No.: HY-W067445
CAS No.: 122-85-0
Synonyms: 4-Acetamidobenzaldehyde
Cat. No.: HY-W250147
CAS No.: 2580-56-5
Synonyms: Victoria blue B
Cat. No.: HY-W739372
CAS No.: 25704-18-1
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Poly (sodium 4-styrenesulfonate) is an anionic cation-exchange polyelectrolyte and metal ion binding/retention agent. It selectively retains Cr III and Fe II under pH 1 conditions, and its retention effect on all tested metal ions is enhanced under higher pH conditions. Poly (sodium 4-styrenesulfonate) inhibits nanosheet aggregation through edge-face interactions between aromatic rings and the graphite surface, thereby stabilizing the dispersion of reduced graphene oxide nanosheets. When incorporated into the mixed Nafion coating of bismuth film electrodes, Poly (sodium 4-styrenesulfonate) improves the reproducibility, stability, sensitivity, and anti-fouling capability for trace metal detection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
