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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1018 Results for "
Detection
" in MedChemExpress (MCE) Product Catalog:
Products (1018)
1018 Results for "Detection" in MCE Product Catalog:
Cat. No.: HY-P4581
CAS No.: 128802-78-8
Synonyms: Suc-ALPF-pNA
Cat. No.: HY-P990847
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Cat. No.: HY-P990872
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Cat. No.: HY-W009311
CAS No.: 1226-46-6
Synonyms: 4,4'-Bis(dimethylamino)thiobenzophenone
Cat. No.: HY-W250149
CAS No.: 1914-99-4
Cat. No.: HY-W587817
CAS No.: 76290-78-3
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6-Sulfatoxymelatonin sodium is a metabolite of Melatonin (HY-B0075) and serves as a detection marker for Melatonin. 6-Sulfatoxymelatonin sodium shows a decreasing trend with increasing age, and its urinary excretion is closely correlated with plasma Melatonin levels, which can reflect changes in the secretion phase of melatonin. 6-Sulfatoxymelatonin sodium is associated with reduced risks of diabetic retinopathy and coronary heart disease, and can act as a biomarker for microvascular and macrovascular complications of type 2 diabetes mellitus. 6-Sulfatoxymelatonin sodium can be used in studies related to type 2 diabetes mellitus and coronary heart disease .
Cat. No.: HY-W923198
CAS No.: 480439-15-4
Synonyms: Methacryloyloxy fluorescein
Cat. No.: HY-164725
CAS No.: 3023869-94-2
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Cat. No.: HY-174790
Firefly Luciferase mRNA is a reporter mRNA that can be transfected into cells to express firefly luciferase protein. Firefly Luciferase mRNA induces cytotoxicity in cancer cells at low concentrations. In cancer cells, the expression level of luciferase shows a non-linear relationship with the dose of Firefly Luciferase mRNA. When combined with the H2S-responsive bioluminescent probe (H-Luc), Firefly Luciferase mRNA enables bioluminescence-based detection of endogenous hydrogen sulfide in non-transgenic NAFLD cell models and NAFLD mouse models. Firefly Luciferase mRNA can be used in studies related to non-alcoholic fatty liver disease .
Cat. No.: HY-175132
Synonyms: NBD L-threo cer (d18:1/12:0); NBD L-threo ceramide (d18:1/12:0); N-Dodecanoyl-NBD L-threo-sphingosine
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C12 NBD L-threo Ceramide (d18:1/12:0) (NBD L-threo cer (d18:1/12:0); NBD L-threo ceramide (d18:1/12:0); N-Dodecanoyl-NBD L-threo-sphingosine) is an NBD fluorescently labeled ceramide analog. C12 NBD L-threo Ceramide (d18:1/12:0) is an isomer of C12 NBD ceramide. C12 NBD L-threo Ceramide (d18:1/12:0) can be used for fluorescence detection, imaging, and kinetic analysis.
Cat. No.: HY-D1701
CAS No.: 130100-20-8
Cat. No.: HY-D1993
Cat. No.: HY-D3000
Cat. No.: HY-D3099
CAS No.: 3078752-74-3
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CSMPP is a ratiometric lysosomal pH fluorescent probe with aggregation-induced emission (AIE) properties, which is used for real-time quantitative detection of lysosomal pH changes in living cells and in vivo. CSMPP has a cyanodistyrene backbone, and contains N-methylpiperazine and pyridine groups (pH-responsive); protonation of the pyridine group significantly enhances intramolecular charge transfer (ICT), leading to green fluorescence emission (Ex/Em = 405/503 nm) under neutral/basic conditions and red fluorescence emission (Ex/Em = 405/615 nm) under acidic conditions. CSMPP exhibits high selectivity, reversibility, good biocompatibility and excellent photostability .
Cat. No.: HY-D3100
CAS No.: 2412201-40-0
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NRTP is a fluorescent probe used for mitochondrial polarity detection and photothermal sensitization. NRTP targets mitochondria via a positively charged triphenylphosphonium moiety, which is attracted by the negative mitochondrial membrane potential; meanwhile, its polarity-sensitive Nile red fluorophore enables it to perceive changes in environmental polarity. NRTP reduces cell viability when used as a photothermal sensitizer. The excitation wavelength is 561 nm, and emission light is collected in two channels: 570-620 nm (red channel) and 665-735 nm (deep red channel). NRTP can reveal the downregulation of mitochondrial polarity during light-induced cell death, as well as polarity changes triggered by exposure to cholesterol .
Cat. No.: HY-D3366
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Th-TMR-S-Halo is a fluorescent probe for HaloTag labeling and live-cell imaging, including super-resolution imaging and real-time visualization of endoplasmic reticulum (ER) vortex formation under ER stress conditions. Th-TMR-S-Halo shows weak fluorescence in the free state, and upon covalent binding to HaloTag, fluorescence activation is achieved by restricting the rotation of the thiophene ring. Th-TMR-S-Halo can be used in studies related to intracellular protein localization, cytoskeleton structure, and ER vortex formation. Live-cell NSPARC super-resolution detection is performed using Ex/Em = 561/570-616 nm .
Cat. No.: HY-D3436
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Pt-Luc is a bioluminescent probe used for real-time, non-invasive monitoring of Pt (IV) prodrug reduction in living cells and animal models. The detection mechanism of Pt-Luc relies on the intracellular reduction mediated by active cysteine residues in proteins. Pt-Luc can penetrate the membrane of living cells; after entering cells, active cysteine thiolates in high-molecular-weight protein components reduce the Pt (IV) complex, thereby cleaving the caged aminoluciferin substrate. The released free aminoluciferin is then oxidized by luciferase in the presence of ATP to generate a bioluminescent signal, whose intensity is directly correlated with the reduction degree of Pt (IV) .
Cat. No.: HY-D3582
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AF633 C5 Maleimide is a fluorescent dye used for surface protein labeling of extracellular vesicles and peptide labeling. AF633 C5 Maleimide covalently binds to protein thiol residues under neutral pH conditions (6.5-7.5), enabling visualization and quantitative analysis of extracellular vesicle uptake by target cells. AF633 C5 Maleimide undergoes maleimide-cysteine conjugation with cysteine residues on peptides in acetonitrile-water buffer solution, supporting detection of peptide-functionalized gold nanorods via confocal laser scanning microscopy, as well as tracking their cellular uptake and localization .
Cat. No.: HY-P11757
CAS No.: 2251785-27-8
Cat. No.: HY-P11936
CAS No.: 2244402-11-5
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GPC3 targeting peptide 2 is a glypican-3 (GPC3) targeting peptide that binds specifically to GPC3 with a Kd of 39.5 nM. GPC3 targeting peptide 2 can be conjugated to IRDye800 via a GGGSC linker for near-infrared fluorescence and photoacoustic imaging, with a tumor-to-adjacent liver fluorescence intensity ratio of approximately 2-fold. GPC3 targeting peptide 2 shows high specificity for immunofluorescence staining of HCC specimens. GPC3 targeting peptide 2 can be used in studies related to GPC3-targeted molecular imaging and early detection of hepatocellular carcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
