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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
127 Results for "
Progesterone Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (127)
127 Results for "Progesterone Receptor" in MCE Product Catalog:
Cat. No.: HY-13676S1
Cat. No.: HY-16508S1
CAS No.: 1621894-62-9
Synonyms: CDB-2914-d3
Cat. No.: HY-P81991A
Synonyms: PGR; NR3C3; Progesterone Receptor; PR; Nuclear Receptor subfamily 3 group C member 3
Cat. No.: HY-P705640
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PAQR7; Progesterone And AdipoQ Receptor Family Member 7; Progestin And AdipoQ Receptor Family Member 7; Membrane Progesterone P4 Receptor Alpha; Progestin And AdipoQ Receptor Family Member VII; Membrane Progesterone Receptor Alpha; Membrane Progestin Rece
Species:
Human
Source:
E. coli Cell-free
Cat. No.: HY-P87283
Synonyms: HPR6.6 antibody; Membrane associated Progesterone Receptor component 1 antibody; Membrane-associated Progesterone Receptor component 1 antibody; mPR antibody; PGRC1_HUMAN antibody; PGRMC antibody; Pgrmc1 antibody; Progesterone binding protein antibody; Progesterone Receptor membrane component 1 antibody
Cat. No.: HY-119080
CAS No.: 532435-68-0
Target:
Research Areas:
CP8754 is an orally active, selective human progesterone receptor (hPR) antagonist that blocks progesterone-mediated signaling pathways. CP8754 competitively inhibits the binding of [ 3H]-progesterone to hPR. And in vitro, CP8754 inhibits progesterone-dependent exogenous luciferase and endogenous alkaline phosphatase expression; while in vivo, CP8754 inhibits rabbit endometrial transformation. CP8754 does not significantly bind to human glucocorticoid receptors (hGR), estrogen receptors (hER), or rat androgen receptors (rAR). CP8754 can be used in the study of progesterone-related diseases such as breast cancer, endometriosis, uterine fibroids, and meningioma, as well as hormone-dependent tumors .
Cat. No.: HY-P87283A
Synonyms: HPR6.6 antibody; Membrane associated Progesterone Receptor component 1 antibody; Membrane-associated Progesterone Receptor component 1 antibody; mPR antibody; PGRC1_HUMAN antibody; PGRMC antibody; Pgrmc1 antibody; Progesterone binding protein antibody; Progesterone Receptor membrane component 1 antibody
Cat. No.: HY-33879
CAS No.: 21440-97-1
Target:
Research Areas:
Brofoxine is a progesterone receptor modulator with anti-anxiety properties .
Cat. No.: HY-B0742S1
Synonyms: 17α-HydroxyProgesterone hexanoate-d8; 17α-HydroxyProgesterone caproate-d8
Cat. No.: HY-183518
CAS No.: 179894-84-9
Research Areas:
LG-120753 is an orally active nonsteroidal progesterone receptor (PR) antagonist, with an IC50 of 38 nM against hPR-B, a Ki of 19 nM against hPR-A, an IC50 of 227 nM against hAR, and IC50 values greater than 1000 nM against hGR, hER and hMR. LG-120753 blocks the action of progesterone, binds to and antagonizes hPR-A, and shows limited cross-reactivity with other steroid receptors. LG-120753 blocks blastocyst implantation, prevents the establishment of pregnancy, exhibits dose-dependent antiprogestogenic activity in vivo, and induces reversible antifertility effects .
Cat. No.: HY-W753635
CAS No.: 1249398-29-5
Research Areas:
EC 313 is a selective progesterone receptor modulator. EC 313 can dose dependently reduce the weight of fibroids. EC 313 can reduce the expression of ER and PR. EC 313 can be used for the study of uterine fibroids .
Cat. No.: HY-11028R
CAS No.: 936345-35-6
Synonyms: PF-2413873 (Standard)
Research Areas:
PF-02413873 (Standard) is the analytical standard of PF-02413873 (HY-11028). This product is intended for research and analytical applications. PF-02413873 (PF-2413873) is a potent selective, fully competitive and orally active nonsteroidal progesterone receptor (PR) antagonist, with a Ki of 2.6 nM. PF-02413873 can block progesterone binding and PR nuclear translocation, and inhibit endometrial growth in vivo .
Cat. No.: HY-B0469S1
Synonyms: MedroxyProgesterone 17-acetate-d7; Farlutin-d7
Cat. No.: HY-W950003
CAS No.: 2917530-31-3
Synonyms: (Rac)-BAY 94-8862-d5
Cat. No.: HY-111372B
CAS No.: 1050477-30-9
Synonyms: (R)-BAY 94-8862
Research Areas:
(R)-Finerenone ((R)-BAY 94-8862) is the R-isomer of Finerenone (HY-111372). Finerenone is a third-generation selective, orally active, non-steroidal mineralocorticoid receptor (MR) antagonist (IC50 = 18 nM). Compared with glucocorticoid receptors (GR), androgen receptors (AR), and progesterone receptors (AR), Finerenone shows good selectivity (> 500-fold). Finerenone has potential application prospects in studies of heart and kidney diseases, such as type 2 diabetes and chronic kidney disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
