Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
138 Results for "
Platelet-activating Factor
" in MedChemExpress (MCE) Product Catalog:
Products (138)
138 Results for "Platelet-activating Factor" in MCE Product Catalog:
Cat. No.: HY-P700567
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; Lp-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-activating Factor Acetylhydrolase, Plas
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P700568
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; Lp-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-activating Factor Acetylhydrolase, Plas
Species:
Mouse
Source:
HEK293
Cat. No.: HY-118915
CAS No.: 50655-20-4
Synonyms: A26771E
Category:
Target:
Cat. No.: HY-N12707
CAS No.: 145722-88-9
Cat. No.: HY-124887
CAS No.: 99046-40-9
Research Areas:
L 651142 is a weak platelet activating factor (PAF) receptor antagonist. L 651142 inhibits the binding of [ 3H]PAF to rabbit platelet, human platelet or human lung membranes with Kis of 0.839 μM, 1.82 μM, 3.64 μM, respectively .
Cat. No.: HY-126551
CAS No.: 474944-25-7
Research Areas:
Butenoyl-PAF is a phospholipid analog of platelet activating factor (PAF-like) that is generated in oxidized low-density lipoprotein (DLDR). Butenoyl-PAF can activate cells that express human PAF receptors, such as neutrophils, monocytes, and platelets, and it stimulates an increase in intracellular calcium ion concentration .
Cat. No.: HY-N10754
CAS No.: 13060-15-6
Target:
Cat. No.: HY-19205B
CAS No.: 205654-37-1
Research Areas:
(2S,5S)-CMI-392 is the absolute configuration of CMI-392 (HY-19205A). CMI-392 is an orally active dual 5-lipoxygenase inhibitor and platelet-activating factor receptor (PAFR) antagonist, with an IC50 of 10 nM for human PAF receptor and an IC50 of 100 nM for rat 5-lipoxygenase. CMI-392 blocks PAF receptor binding, inhibits leukotriene synthesis, attenuates PAF-induced hemoconcentration, and suppresses arachidonic acid- and TPA-induced ear swelling in mice. CMI-392 reduces inflammatory cell infiltration, decreases MPO levels, alleviates ocular inflammation, and improves dextran sulfate sodium-induced colitis. CMI-392 can be used in the research of inflammatory and immune-related diseases such as colitis and atopic dermatitis .
Research Areas:
CV-6209 is a potent antagonist of platelet activating factor (PAF). CV-6209 inhibits the PAF-induced aggregation of rabbit and human platelets, with IC50s of 75 nM and 170 nM, respectively. CV-6209 can inhibit PAF-induced hypotension in rats .
Cat. No.: HY-N14932
CAS No.: 19207-26-2
Category:
Cat. No.: HY-N14933
CAS No.: 104700-85-8
Category:
Cat. No.: HY-N14934
CAS No.: 104700-86-9
Category:
Cat. No.: HY-108908R
CAS No.: 122956-68-7
Synonyms: UK-74505 (Standard)
Research Areas:
(Rac)-Modipafant (Standard) is the analytical standard of (Rac)-Modipafant (HY-108908). This product is intended for research and analytical applications. (Rac)-Modipafant (UK-74505) is an orally active, selective, long-acting irreversible platelet activating factor receptor (PAFR) antagonist. (Rac)-Modipafant prevents dengue infection .
Cat. No.: HY-102004R
CAS No.: 412950-08-4
Synonyms: SB 659032 (Standard)
Target:
Research Areas:
Rilapladib (Standard) is the analytical standard of Rilapladib (HY-102004). This product is intended for research and analytical applications. Rilapladib (SB 659032) is a selective Lp-PLA2 (lipoprotein-associated phospholipase A2) inhibitor with an IC50 of 230 pM . Rilapladib (SB 659032) is also a PAFR (Platelet Activating Factor Receptor) antagonist .
Cat. No.: HY-182418
CAS No.: 138060-13-6
Research Areas:
UR-11353 is a selective platelet activating factor (PAF) antagonist with long-lasting activity. UR-11353 inhibits PAF-induced platelet aggregation in rabbit platelet-rich plasma. UR-11353 inhibits PAF-induced hypotension in normotensive rats. UR-11353 protects against PAF-induced mortality in mice .
Cat. No.: HY-19121A
CAS No.: 121494-09-5
Research Areas:
TCV-309 chloride is a potent and specific platelet activating factor (PAF) antagonist. TCV-309 chloride specifically inhibits PAF-induced aggregation of rabbit and human platelets, and [3H]PAF binding to rabbit platelet microsomes with IC50 values of 33 nM, 58 nM and 27 nM, respectively. TCV-309 chloride has beneficial effects in anaphylactic shock .
Cat. No.: HY-100164R
CAS No.: 114606-56-3
Synonyms: MKS 492 (Standard)
Research Areas:
SDZ-MKS 492 (Standard) is the analytical standard of SDZ-MKS 492 (HY-100164). This product is intended for research and analytical applications. SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE). SDZ-MKS 492 inhibits antigen- or platelet activating factor (PAF)-induced bronchoconstriction and allergic reactions in guinea pigs and rats .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
