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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
287 Results for "
Crumbs3 transcript
" in MedChemExpress (MCE) Product Catalog:
Products (287)
287 Results for "Crumbs3 transcript" in MCE Product Catalog:
Art. -Nr.: HY-189358
CAS. Nr.: 901730-21-0
Target:
Forschungsgebiete:
TACR1-IN-1 is a TACR1 inhibitor. TACR1-IN-1 attenuates Substance P-driven ERK phosphorylation and downstream malignant programs. TACR1-IN-1 reduces PGP9.5-positive tumor innervation in orthotopic PDAC models. TACR1-IN-1 increases antigen presentation and immune chemokine-related transcript expression under Substance P treatment conditions. TACR1-IN-1 reverses Substance P-associated reduction in Gemcitabine (HY-17026) sensitivity. TACR1-IN-1 can be used for research on pancreatic ductal adenocarcinoma .
Art. -Nr.: HY-147412
CAS. Nr.: 2642382-41-8
Synonyms: QR-421a
Forschungsgebiete:
Ultevursen (QR-421a) is a splice-modulating antisense oligonucleotide targeting exon 13 of the USH2A gene, which restores the functional expression of Usherin protein by inducing exon skipping. Ultevursen binds to USH2A pre-mRNA and modulates the splicing process to specifically skip exon 13 carrying the pathogenic mutation c.2299delG, generating an in-frame transcript and a truncated yet functionally normal protein. Ultevursen exhibits concentration-dependent exon skipping activity in human cells and retinal organoid models, and restores Usherin expression and retinal function in zebrafish and gene-edited mouse models. Ultevursen can be used for related research on type 2 Usher syndrome and non-syndromic retinitis pigmentosa .
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RNA, (P-thio)[2′-O-(2-methoxyethyl)](A-G-m5C-m5U-m5U-m5C-G-G-A-G-A-A-A-m5U-m5U-m5U-A-A-A-m5U-m5C), sodium salt
Art. -Nr.: HY-147412A
Synonyms: QR-421a sodium
Art. -Nr.: HY-178053
CAS. Nr.: 1191937-43-5
Forschungsgebiete:
AHR agonist 10 is a potent AHR agonist (EC50 = 2.01 nM). AHR agonist 10 can elevate the transcript levels of key AHR downstream pathway target genes, including CYP1A1 and CYP1B1. AHR agonist 10 can downregulate the expression levels of CD36, IL-18 and shows low cytotoxicity (>40 μM) to normal cells. AHR agonist 10 can suppress the expression of CCL5, CCL20, IL-6, IL-8, S100A9, TLR4, TNF-α, and TNFR1, demonstrating that AHR agonist 10 effectively modulate inflammatory responses through AHR dependent signaling pathways. AHR agonist 10 can be used for psoriasis research .
Art. -Nr.: HY-P2200
CAS. Nr.: 164802-68-0
Synonyms: BMY-29304
Target:
Forschungsgebiete:
Art. -Nr.: HY-P7509
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL7; Angiopoietin-Like Protein 7; Angiopoietin Like 7; Angiopoietin-Like Factor (CDT6); CDT6; Angiopoietin-Like Factor; AngX; Angiopoietin-Like 7; Cornea-Derived transcript 6 Protein; DJ647M16.1; Angiopoietin-Related Protein 7
Species:
Human
Source:
HEK293
Art. -Nr.: HY-P70162
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LILRA3; Immunoglobulin-Like transcript 6; Leukocyte Immunoglobulin Like Receptor A3; Leucocyte Ig-Like Receptor A3; LIR-4; CD85e; ILT6; ILT-6; LIR4; HM43; Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3; HM31; Leukocyte I
Species:
Human
Source:
HEK293
Art. -Nr.: HY-P71382
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TREML1; TLT-1; Triggering Receptor Expressed On Myeloid Cells Like 1; Triggering Receptor Expressed On Myeloid Cells-Like 1; TLT1; TREM-Like transcript 1; DJ238O23.3; GLTL1825; Triggering Receptor Expressed On Myeloid Cells-Like Protein 1; PRO3438; Trem-L
Species:
Human
Source:
HEK293
Art. -Nr.: HY-P72518
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LILRB4; CD85 Antigen-Like Family Member K; Leukocyte Immunoglobulin Like Receptor B4; Monocyte Inhibitory Receptor HM18; LIR-5; Immunoglobulin-Like transcript 3; ILT3; Leucocyte Ig-Like Receptor B4; LIR5; ILT-3; CD85k; HM18; Leukocyte Immunoglobulin-Like
Species:
Mouse
Source:
HEK293
Art. -Nr.: HY-P72519
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LILRB4; CD85 Antigen-Like Family Member K; Leukocyte Immunoglobulin Like Receptor B4; Monocyte Inhibitory Receptor HM18; LIR-5; Immunoglobulin-Like transcript 3; ILT3; Leucocyte Ig-Like Receptor B4; LIR5; ILT-3; CD85k; HM18; Leukocyte Immunoglobulin-Like
Species:
Human
Source:
HEK293
Art. -Nr.: HY-P75507
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL7; Angiopoietin-Like Protein 7; Angiopoietin Like 7; Angiopoietin-Like Factor (CDT6); CDT6; Angiopoietin-Like Factor; AngX; Angiopoietin-Like 7; Cornea-Derived transcript 6 Protein; DJ647M16.1; Angiopoietin-Related Protein 7
Species:
Canine
Source:
HEK293
Art. -Nr.: HY-P75508
Reinheit: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL7; Angiopoietin-Like Protein 7; Angiopoietin Like 7; Angiopoietin-Like Factor (CDT6); CDT6; Angiopoietin-Like Factor; AngX; Angiopoietin-Like 7; Cornea-Derived transcript 6 Protein; DJ647M16.1; Angiopoietin-Related Protein 7
Species:
Canine
Source:
HEK293
Art. -Nr.: HY-P75866
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LILRB4; CD85 Antigen-Like Family Member K; Leukocyte Immunoglobulin Like Receptor B4; Monocyte Inhibitory Receptor HM18; LIR-5; Immunoglobulin-Like transcript 3; ILT3; Leucocyte Ig-Like Receptor B4; LIR5; ILT-3; CD85k; HM18; Leukocyte Immunoglobulin-Like
Species:
Mouse
Source:
HEK293
Art. -Nr.: HY-P76440
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LILRB4; CD85 Antigen-Like Family Member K; Leukocyte Immunoglobulin Like Receptor B4; Monocyte Inhibitory Receptor HM18; LIR-5; Immunoglobulin-Like transcript 3; ILT3; Leucocyte Ig-Like Receptor B4; LIR5; ILT-3; CD85k; HM18; Leukocyte Immunoglobulin-Like
Species:
Human
Source:
HEK293
Art. -Nr.: HY-P76441
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LILRB4; CD85 Antigen-Like Family Member K; Leukocyte Immunoglobulin Like Receptor B4; Monocyte Inhibitory Receptor HM18; LIR-5; Immunoglobulin-Like transcript 3; ILT3; Leucocyte Ig-Like Receptor B4; LIR5; ILT-3; CD85k; HM18; Leukocyte Immunoglobulin-Like
Species:
Human
Source:
HEK293
Art. -Nr.: HY-P77738
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: LILRB4; CD85 Antigen-Like Family Member K; Leukocyte Immunoglobulin Like Receptor B4; Monocyte Inhibitory Receptor HM18; LIR-5; Immunoglobulin-Like transcript 3; ILT3; Leucocyte Ig-Like Receptor B4; LIR5; ILT-3; CD85k; HM18; Leukocyte Immunoglobulin-Like
Species:
Cynomolgus
Source:
HEK293
Art. -Nr.: HY-P77743
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: LILRB4; CD85 Antigen-Like Family Member K; Leukocyte Immunoglobulin Like Receptor B4; Monocyte Inhibitory Receptor HM18; LIR-5; Immunoglobulin-Like transcript 3; ILT3; Leucocyte Ig-Like Receptor B4; LIR5; ILT-3; CD85k; HM18; Leukocyte Immunoglobulin-Like
Species:
Human
Source:
HEK293
Art. -Nr.: HY-P77744
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: LILRB4; CD85 Antigen-Like Family Member K; Leukocyte Immunoglobulin Like Receptor B4; Monocyte Inhibitory Receptor HM18; LIR-5; Immunoglobulin-Like transcript 3; ILT3; Leucocyte Ig-Like Receptor B4; LIR5; ILT-3; CD85k; HM18; Leukocyte Immunoglobulin-Like
Species:
Human
Source:
HEK293
Art. -Nr.: HY-P77984
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: LILRA3; Immunoglobulin-Like transcript 6; Leukocyte Immunoglobulin Like Receptor A3; Leucocyte Ig-Like Receptor A3; LIR-4; CD85e; ILT6; ILT-6; LIR4; HM43; Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3; HM31; Leukocyte I
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
