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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
185 Results for "
Intestine
" in MedChemExpress (MCE) Product Catalog:
Products (185)
185 Results for "Intestine" in MCE Product Catalog:
Cat. No.: HY-P81368A
Synonyms: AKR1B10; AKR1B11; Aldo-keto reductase family 1 member B10; ARL-1; Aldose reductase-like; Aldose reductase-related protein (ARP; hARP); Small Intestine reductase (SI reductase)
Cat. No.: HY-133676
CAS No.: 40321-98-0
Synonyms: MEOHP; 5-oxo-MEHP
Target:
Research Areas:
Mono (2-ethyl-5-oxohexyl) phthalate (MEOHP; 5-oxo-MEHP) is a secondary metabolite produced by cytochrome P450 enzyme-mediated oxidation of di(2-ethylhexyl) phthalate. Exposure levels of Mono (2-ethyl-5-oxohexyl) phthalate are associated with late-onset hypogonadism. Mono (2-ethyl-5-oxohexyl) phthalate can be used for research on mechanisms related to male reproductive endocrine disorders .
Cat. No.: HY-133676S
CAS No.: 679789-44-7
Synonyms: MEOHP-d4; 5-oxo-MEHP-d4
Research Areas:
Mono(2-ethyl-5-oxohexyl) phthalate-d4 (MEOHP-d4; 5-oxo-MEHP-d4) is the deuterated-labeled Mono(2-ethyl-5-oxohexyl) phthalate (HY-133676). Mono (2-ethyl-5-oxohexyl) phthalate (MEOHP; 5-oxo-MEHP) is a secondary metabolite produced by cytochrome P450 enzyme-mediated oxidation of di(2-ethylhexyl) phthalate. Exposure levels of Mono (2-ethyl-5-oxohexyl) phthalate are associated with late-onset hypogonadism. Mono (2-ethyl-5-oxohexyl) phthalate can be used for research on mechanisms related to male reproductive endocrine disorders .
Cat. No.: HY-P2074
CAS No.: 128657-36-3
Target:
Research Areas:
Cat. No.: HY-178028
CAS No.: 3113303-04-8
Target:
Research Areas:
PRMT5-IN-53 is a gut-restricted and orally active PRMT5 inhibitor with pIC50s of ≥ 9.7 against hPRMT5 and mPRMT5. PRMT5-IN-53 binds to the PRMT5:MEP50 complex with a KD of 11.3 pM. PRMT5-IN-53 effectively inhibits PRMT5 locally in the intestines of mice, significantly reducing the number and area of polyps, while avoiding systemic hematological toxicity (such as anemia, neutropenia). PRMT5-IN-53 can be used for the study of colorectal cancer especially for familial adenomatous polyposis (FAP) .
Cat. No.: HY-155801
CAS No.: 216014-14-1
Research Areas:
Cardiovascular Disease Infection Neurological Disease Inflammation/Immunology Cancer
CRX 527 is a TLR4 agonist. CRX 527 activates the MyD88-dependent, TRIF-dependent, and TRAF6/NF-κB signaling pathways downstream of TLR4, mimics lipid A, and regulates antigen processing and presentation by dendritic cells. CRX 527 stimulates innate immune responses and enhances vaccine efficacy. CRX 527 maintains the structural integrity of hematopoietic tissues, spleen and intestine, alleviates radiation-induced damage, preserves intestinal homeostasis, and inhibits apoptosis, inflammatory responses, oxidative stress and DNA damage. CRX 527 can be used in the research of acute radiation syndrome, melanoma, HPV-related tumors and intracerebral hemorrhage .
Category:
Target:
Target:
Research Areas:
Amprolium is a thiamine transporter inhibitor and antiparasitic agent with oral activity and blood-brain barrier penetration. Amprolium blocks thiamine transport at the blood-brain barrier and intestine, and competitively inhibits thiamine pyrophosphokinase, inducing thiamine pyrophosphate deficiency and impairing carbohydrate synthesis. Amprolium induces oxidative stress, alters antioxidant enzyme activity, and inhibits acetylcholinesterase (AchE) activity. Amprolium disrupts reproductive organs and gametogenesis, and causes histopathological and ultrastructural damage to multiple organs. Amprolium induces thiamine deficiency, reduces body weight gain in mice, and causes psychomotor behavioral changes and nephropathy. Amprolium exhibits molluscicidal activity against the terrestrial snail Eobania vermiculata, and reduces the shedding of Eimeria meleagrimitis oocysts in feces and litter. Amprolium can be used for research on thiamine deficiency and coccidiosis .
Target:
Research Areas:
Amprolium hydrochloride is a thiamine transporter inhibitor and antiparasitic agent with oral activity and blood-brain barrier penetration. Amprolium hydrochloride blocks thiamine transport at the blood-brain barrier and intestine, and competitively inhibits thiamine pyrophosphokinase, inducing thiamine pyrophosphate deficiency and impairing carbohydrate synthesis. Amprolium hydrochloride induces oxidative stress, alters antioxidant enzyme activity, and inhibits acetylcholinesterase (AchE) activity. Amprolium hydrochloride disrupts reproductive organs and gametogenesis, and causes histopathological and ultrastructural damage to multiple organs. Amprolium hydrochloride induces thiamine deficiency, reduces body weight gain in mice, and causes psychomotor behavioral changes and nephropathy. Amprolium hydrochloride exhibits molluscicidal activity against the terrestrial snail Eobania vermiculata, and reduces the shedding of Eimeria meleagrimitis oocysts in feces and litter. Amprolium hydrochloride can be used for research on thiamine deficiency and coccidiosis .
Cat. No.: HY-N21609
CAS No.: 60462-09-1
Target:
Cat. No.: HY-P7699
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDH17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:
Human
Source:
HEK293
Cat. No.: HY-P76755
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDH17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:
Rat
Source:
HEK293
Cat. No.: HY-P77309
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CDH17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P77627
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CDH17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P77895
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CDH17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P700688
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDH17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:
Human
Source:
HEK293
Cat. No.: HY-P701972
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKR1B10; HSI; Prev. AKR1B11; Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase); ARL-1; Aldose Reductase-Like Peptide; Aldose Reductase-Related Protein; Aldose Reductase-Like 1; Small Intestine Reductase; SI Reductase; AKR1B12; HARP; ALDRLn; ARP
Species:
Human
Source:
E. coli
Cat. No.: HY-P704423
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDH17; Human Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17; Human Peptide Transporter 1; Liver-Intestine Cadherin; HPT-1 Cadherin; Cadherin-17; LI Cadherin; HPT-1; Cadherin-16; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; C
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P76192
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES2; Carboxylesterase 2 (Intestine, Liver); Carboxylesterase 2; Cocaine Esterase; CE-2; Intestinal Carboxylesterase; Liver Carboxylesterase-2; ICE; Carboxylic Ester Hydrolase; CES2A1; PCE-2; Methylumbelliferyl-Acetate Deacetylase 2; HCE-2
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
