137-88-2
Chemical Structure
Amprolium hydrochloride
- CAS No.: 137-88-2
- Formula:C14H20Cl2N4
- Molecular Weight:315.24
IUPAC Name: 1-((4-amino-2-propylpyrimidin-5-yl)methyl)-2-methylpyridin-1-ium chloride hydrochloride
InChIKey: PJBQYZZKGNOKNJ-UHFFFAOYSA-M
SMILES: CC1=CC=CC=[N+]1CC2=CN=C(CCC)N=C2N.[Cl-].Cl
Biological Activity: Amprolium hydrochloride is an anti-parasitic drug that's kind of taken orally, and it acts as an antagonist to thiamine in intestinal absorption[1][2][3][4].
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Amprolium hydrochloride | 98.79% | Amprolium hydrochloride is an anti-parasitic drug that's kind of taken orally, and it acts as an antagonist to thiamine in intestinal absorption. | ||||||||||||||||||||
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Amprolium hydrochloride (Standard) | ≥98% | Amprolium (hydrochloride) (Standard) is the analytical standard of Amprolium (hydrochloride). This product is intended for research and analytical applications. Amprolium hydrochloride is an anticoccidial drug used in poultry. It is a thiamine-like substance that inhibits thiamine transport in coccidia by inhibiting thiamine absorption and carbohydrate synthesis. | ||||||||||||||||||||
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- [1]. Kennedy O Ogolla, et al. Efficacy of Sulphachloropyrazine, Amprolium Hydrochloride, Trimethoprim-Sulphamethoxazole, and Diclazuril against Experimental and Natural Rabbit Coccidiosis. J Vet Med. 2018 Oct 23:2018:5402469. [Content Brief]
- [2]. G Rindi, et al. Action of Amprolium on the thiamine content of rat tissues. J Nutr. 1966 Jun;89(2):197-202. [Content Brief]
- [3]. Iqbal A, et al. Antiparasitic efficacy of Artemisia absinthium, toltrazuril and amprolium against intestinal coccidiosis in goats. J Parasit Dis. 2013 Apr;37(1):88-93. [Content Brief]
- [4]. Lindsay DS, et al. Effects of sulfadiazine and amprolium on Neospora caninum (Protozoa: Apicomplexa) infections in mice. J Parasitol. 1990 Apr;76(2):177-9. [Content Brief]