16 Results for "

α-Lipoic Acid

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "α-Lipoic Acid" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-N0492
CAS No.: 1077-28-7
Synonyms: Thioctic Acid; (±)-α-Lipoic Acid; DL-α-Lipoic Acid
α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .
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11
11 Cited Publications
Cat. No.: HY-18733
CAS No.: 1200-22-2
Synonyms: (R)-(+)-α-Lipoic Acid; R-(+)-Thioctic Acid
Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.
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14
14 Publications Verification
Cat. No.: HY-N0492A
CAS No.: 2319-84-8
Synonyms: Thioctic Acid sodium; (±)-α-Lipoic Acid sodium; DL-α-Lipoic Acid sodium
α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .
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3
3 Cited Publications
Cat. No.: HY-141336
CAS No.: 40846-94-4
Purity:  ≥98.0%
Synonyms: DL-α-Lipoic Acid-NHS
Target:  

PROTAC Linkers

Research Areas:  

Cancer

α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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1
1 Cited Publications
Cat. No.: HY-N0492S
CAS No.: 1189471-66-6
Synonyms: Thioctic Acid-d5; (±)-α-Lipoic Acid-d5; DL-α-Lipoic Acid-d5
α-Lipoic Acid-d5 is the deuterium labeled α-Lipoic Acid. α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells .
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1
1 Cited Publications
Cat. No.: HY-18733R
CAS No.: 1200-22-2
Synonyms: (R)-(+)-α-Lipoic Acid(Standard); R-(+)-Thioctic Acid (Standard)
Lipoic acid (Standard) is the analytical standard of Lipoic acid. This product is intended for research and analytical applications. Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.
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Cat. No.: HY-134633
CAS No.: 1808266-58-1
Synonyms: EV 06 chloride; UNR 844 chloride
Target:  

Drug Intermediate

Research Areas:  

Neurological Disease

Alpha-lipoic acid choline ester (EV 06) chloride is choline ester of alpha-lipoic acid. Alpha-lipoic acid choline ester chloride reduces the disulfide bond level of lens proteins. Alpha-lipoic acid choline ester chloride improves lens elasticity. Alpha-lipoic acid choline ester chloride is hydrolyzed by ocular esterases to release alpha-lipoic acid and choline. Alpha-lipoic acid choline ester chloride is used for the research of presbyopia .
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Cat. No.: HY-119152
CAS No.: 910627-26-8
Purity:  99.42%
Research Areas:  

Others

CMX-2043 is a novel analogue of α-Lipoic Acid (HY-N0492). CMX-2043 is effective in antioxidant effect, activation of insulin receptor kinase, soluble tyrosine kinase, and Akt phosphorylation. CMX-2043 shows protection against ischemia-reperfusion injury (IRI) in rat model .
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Cat. No.: HY-N0492R
CAS No.: 1077-28-7
Synonyms: Thioctic Acid (Standard); (±)-α-Lipoic Acid (Standard); DL-α-Lipoic Acid (Standard)
α-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid. This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .
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Cat. No.: HY-151802
CAS No.: 2043660-80-4
Target:  

TrxR

Research Areas:  

Cancer

CPUL1 is a TrxR inhibitor, which shows proliferation-inhibitory and anti-metastatic activity against A549 cells. CPUL1 influences EMT (epithelial-mesenchymal transition) via inducing ROS-mediated ERK/JNK signaling by inhibiting TrxR1 enzyme activity. CPUL1 in combination with α-Lipoic Acid (HY-N0492) or Dithiodipropionic acid (HY-W014395) is more effective .
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Cat. No.: HY-N0492AR
CAS No.: 2319-84-8
Synonyms: Thioctic Acid sodium (Standard); (±)-α-Lipoic Acid sodium (Standard); DL-α-Lipoic Acid sodium (Standard)
α-Lipoic Acid (sodium) (Standard) is the analytical standard of α-Lipoic Acid (sodium). This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1.
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Cat. No.: HY-120974
CAS No.: 691410-93-2
Target:  

GLUT

Research Areas:  

Metabolic Disease

α-Lipoic Acid Derivative 1 (Compound AN-7) is an α-lipoic acid derivative that enhances glucose transport in skeletal muscle by releasing active α-lipoic acid (LA), significantly improving glucose metabolism. In L6 skeletal muscle cells, α-Lipoic Acid Derivative 1 significantly increases glucose transport rates, approximately 12 times more potent than the parent compound α-lipoic acid (HY-N0492). In a mild diabetic mouse model, 10 mg/kg of α-Lipoic Acid Derivative 1 administered for two weeks significantly reduced blood glucose levels by 39%. α-Lipoic Acid Derivative 1 shows significant potential in research related to glucose metabolism in diabetes .
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Cat. No.: HY-18733S
CAS No.: 1448263-85-1
Synonyms: (R)-(+)-α-Lipoic Acid-d4; R-(+)-Thioctic Acid-d4
Lipoic acid-d4 ((R)-(+)-α-Lipoic acid-d4) is deuterium labeled Lipoic acid. Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid .
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Cat. No.: HY-18733G
CAS No.: 1200-22-2
Synonyms: (R)-(+)-α-Lipoic Acid (GMP); R-(+)-Thioctic Acid (GMP)
Lipoic acid (GMP) ((R)-(+)-α-Lipoic acid (GMP)) is Lipoic acid (HY-18733) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.
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Cat. No.: HY-183808
CAS No.: 1255918-84-3
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

N-(1,2-Dithiolane-3-pentanoyl)-Glu-Ala is a derivative of DL-α-lipoic acid (HY-N0492). N-(1,2-Dithiolane-3-pentanoyl)-Glu-Ala can be used for the research of ischemic and ischemia-reperfusion injuries .
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Cat. No.: HY-W839206
CAS No.: 3737-39-1
Target:  

NO Synthase

Research Areas:  

Neurological Disease

NOS-IN-4 (Compound 3) is a neuronal nitric oxide synthase (nNOS) inhibitor with an IC50 of 4.00 μM that inhibits nNOS activity. The combined use of alpha-lipoic acid and NOS-IN-4 has a protective effect against MPTP (HY-W114750)-induced dopamine depletion in the mouse brain. NOS-IN-4 can be used for the research of neurological disease .
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