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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
β-secretase 1
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "β-secretase 1" in MCE Product Catalog:
Target:
Research Areas:
NB-360 is a potent, brain penetrable and orally active β‐secretase 1/2 (BACE1/BACE2) dual inhibitor with IC50 values of 5 and 6 nM. NB-360 can inhibit amyloid-β protein accumulation. NB-360 can be used for the researches of inflammation and neurological disease, such as Alzheimer's disease .
Cat. No.: HY-N1280
CAS No.: 129280-33-7
Category:
Flavonoids Leguminosae Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch. Isoflavones
Target:
Cat. No.: HY-P1962
CAS No.: 350228-37-4
Synonyms: [Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)
Target:
Research Areas:
Cat. No.: HY-149211
Research Areas:
AChE/BChE-IN-12 (compound 10b), a 3,5-dimethoxy analogue, is a potent AChE, BChE, and β-secretase-1 (BACE-1) inhibitor, with IC50 values of 2.57, 3.26, and 10.65 μM, respectively. AChE/BChE-IN-12 crosses the blood-brain barrier via passive diffusion and inhibits the self-aggregation of amyloid-β monomers. AChE/BChE-IN-12 can be used for Alzheimer’s disease (AD) research .
Cat. No.: HY-157527
CAS No.: 2978613-03-3
Target:
Research Areas:
hAChE-IN-7 (compound 5s) is a mixed inhibitor affecting both the catalytic active site (CAS) and peripheral anionic site (PAS) of hAChE. hAChE-IN-7 displays the balanced inhibitory effect on hAChE (IC50=69.8 nM) and hBuChE (IC50=68.0 nM), and exhibits inhibitory activity against β-secretase-1 (BACE-1) (IC50=3.6 μM). hAChE-IN-7 has the potential for Alzheimer's disease (AD) research .
Cat. No.: HY-112444
CAS No.: 1352416-78-4
Target:
Research Areas:
BACE1-IN-2 is a 1,4-Oxazine β-Secretase 1 (BACE1) inhibitor with an IC50 of 22 nM .
Cat. No.: HY-P4919
CAS No.: 1802078-31-4
Target:
Research Areas:
Cat. No.: HY-P72840
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic Protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl Protease 2; Transmembrane Aspartic Prot
Species:
Human
Source:
HEK293
Cat. No.: HY-P82169
Synonyms: BACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2
Cat. No.: HY-P86180
Synonyms: BACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2
Cat. No.: HY-P85420
Synonyms: BACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2
Cat. No.: HY-P72843
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic Protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl Protease 2; Transmembrane Aspartic Prot
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P700606
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic Protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl Protease 2; Transmembrane Aspartic Prot
Species:
Human
Source:
HEK293
Cat. No.: HY-P72842
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic Protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl Protease 2; Transmembrane Aspartic Prot
Species:
Human
Source:
HEK293
Cat. No.: HY-P77569
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic Protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl Protease 2; Transmembrane Aspartic Prot
Species:
Human
Source:
HEK293
Cat. No.: HY-P704472
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE1; CDNA FLJ54690, Highly Similar To Beta-secretase 1; Prev. BACE; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_f; Membrane-Associated Aspartic Protease 2; Beta-Site APP-Cleaving Enzyme 1, Isoform CRA_e; Aspartyl Protease 2; Transmembrane Aspartic Prot
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
