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AChE/BChE-IN-12

AChE/BChE-IN-12 (compound 10b), a 3,5-dimethoxy analogue, is a potent AChE, BChE, and β-secretase-1 (BACE-1) inhibitor, with IC50 values of 2.57, 3.26, and 10.65 μM, respectively. AChE/BChE-IN-12 crosses the blood-brain barrier via passive diffusion and inhibits the self-aggregation of amyloid-β monomers. AChE/BChE-IN-12 can be used for Alzheimer’s disease (AD) research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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  • 分子式: C23H21N3O6
  • 分子量:435.43
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • AChE/BChE-IN-12 Chemical Structure
    AChE/BChE-IN-12 構造式
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Cholinesterase (ChE) アイソフォーム固有の製品をすべて表示

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  • AChE/BChE-IN-12 Chemical Structure
    AChE/BChE-IN-12 Chemical Structure
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  • AChE/BChE-IN-12