hAChE-IN-7
hAChE-IN-7 (compound 5s) is a mixed inhibitor affecting both the catalytic active site (CAS) and peripheral anionic site (PAS) of hAChE. hAChE-IN-7 displays the balanced inhibitory effect on hAChE (IC50=69.8 nM) and hBuChE (IC50=68.0 nM), and exhibits inhibitory activity against β-secretase-1 (BACE-1) (IC50=3.6 μM). hAChE-IN-7 has the potential for Alzheimer's disease (AD) research.
For research use only. We do not sell to patients.
- CAS No.: 2978613-03-3
- Formula: C38H55N3O3
- Molecular Weight:601.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2978613-03-3
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Molecular Weight 601.86
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Formula C38H55N3O3
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SMILES
COC1=C(C=CC(CNC(CCCCCCC(C)C)=O)=C1)OCCCCCCCNC2=C3C=CC=CC3=NC4=C2CCCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hAChE-IN-7 Related Classifications
HY-157527 Related Classifications
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