5 Results for "

Suberoylanilide hydroxamic acid

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Suberoylanilide hydroxamic acid" in MCE Product Catalog:

175
175 Cited Publications
Cat. No.: HY-10221
CAS No.: 149647-78-9
Purity:  99.58%
Synonyms: SAHA; Suberoylanilide hydroxamic acid
Research Areas:  

Infection Cancer

Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis . Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification .
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Cat. No.: HY-10221R
CAS No.: 149647-78-9
Synonyms: SAHA (Standard); Suberoylanilide hydroxamic acid (Standard)
Vorinostat (Standard) is the analytical standard of Vorinostat. This product is intended for research and analytical applications. Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis . Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification .
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Cat. No.: HY-115412
CAS No.: 1132749-48-4
Purity:  ≥99.0%
Synonyms: SAHA-d5; Suberoylanilide hydroxamic acid-d5
Research Areas:  

Infection Cancer

Vorinostat-d5 (SAHA-d5) is the deuterium labeled Vorinostat. Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis . Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification .
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Cat. No.: HY-10221G
CAS No.: 149647-78-9
Synonyms: SAHA (GMP); Suberoylanilide hydroxamic acid (GMP)
Vorinostat (GMP) is a GMP grade Vorinosta (HY-10221). GMP-grade small molecules can be used as auxiliary agents in cell therapy. Vorinostat is a potent, orally available HDAC1, HDAC2, HDAC3 (Class I), HDAC6 and Inhibitors of HDAC7 (Class II) and Class IV (HDAC11) .
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Cat. No.: HY-W016689
CAS No.: 2010-06-2
Target:  

Drug Intermediate

Research Areas:  

Cancer

2-Amino-4-phenylthiazole is a synthetic intermediate useful for pharmaceutical synthesis. 2-Amino-4-phenylthiazole can be used to synthesize suberoylanilide hydroxamic acid (SAHA) analogs with cancer cell growth inhibitory activities. 2-Amino-4-phenylthiazole also can be used to synthesize ketone histone deacetylase inhibitors with antitumor activity in vivo .
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