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1-Methylimidazoleacetic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CD38 (1) Endogenous Metabolite (3) Ferroportin (1) Isotope-Labeled Compounds (1) Opioid Receptor (1) Reference Standards (1)
By Research Areas:	Cancer (1) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

HY-13936

1-Methylimidazoleacetic acid 1-Methylimidazole-4-acetic acid	Endogenous Metabolite	Others
1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid) is a histamine metabolite in urine that can be used in the study of mastocytosis .

HY-13936R

1-Methylimidazoleacetic acid (Standard) 1-Methylimidazole-4-acetic acid (Standard)	Reference Standards Endogenous Metabolite	Others
1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid) (Standard) is the analytical standard of 1-Methylimidazoleacetic acid. This product is intended for research and analytical applications. 1-Methylimidazoleacetic acid is a Histamine (HY-B1204) metabolite. 1-Methylimidazoleacetic acid serves as a biomarker for the detection of mastocytosis .

HY-13936S

1-Methylimidazoleacetic acid-d3 1-Methylimidazole-4-acetic acid-d₃	Isotope-Labeled Compounds Endogenous Metabolite	Others
1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid)-d₃ is deuterium labeled 1-Methylimidazoleacetic acid (HY-13936). 1-Methylimidazoleacetic acid is a Histamine (HY-B1204) metabolite. 1-Methylimidazoleacetic acid serves as a biomarker for the detection of mastocytosis .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-109166

Amdakefalin	Opioid Receptor	Neurological Disease
Amdakefalin is a μ and δ opioid receptors agonist with analgesic effects .

Cat. No.	Product Name	Target	Research Area

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-109166

Amdakefalin	Opioid Receptor	Neurological Disease
Amdakefalin is a μ and δ opioid receptors agonist with analgesic effects .

Cat. No.	Product Name	Chemical Structure

HY-13936S

1-Methylimidazoleacetic acid-d3
1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid)-d₃ is deuterium labeled 1-Methylimidazoleacetic acid (HY-13936). 1-Methylimidazoleacetic acid is a Histamine (HY-B1204) metabolite. 1-Methylimidazoleacetic acid serves as a biomarker for the detection of mastocytosis .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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