![tert-Butyl (1S,4S,5R)-5-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate](https://file.medchemexpress.com/product_pic/hy-34550a.gif "Click to View tert-Butyl (1S,4S,5R)-5-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate Product Detail")
![(2S,5R)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide](https://file.medchemexpress.com/product_pic/hy-79858.gif "Click to View (2S,5R)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
261 Results for "
5R
" in MedChemExpress (MCE) Product Catalog:
Products (261)
261 Results for "5R" in MCE Product Catalog:
3
3 Cited Publications
Art. -Nr.: HY-P0227
CAS. Nr.: 168482-23-3
Target:
Forschungsgebiete:
1
1 Cited Publications
Art. -Nr.: HY-19969
CAS. Nr.: 163769-88-8
Target:
Forschungsgebiete:
YM-90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).YM-90709 potently inhibits the binding of [ 125I]-IL-5 to IL-5R on human peripheral eosinophils and eosinophilic HL-60 clone 15 cells with IC50 values of 1.0 and 0.57 μM .
1
1 Cited Publications
Art. -Nr.: HY-P9923
CAS. Nr.: 1044511-01-4
Synonyms: MEDI-563; BIW-8405; KHK4563
Target:
Forschungsgebiete:
1
1 Cited Publications
Art. -Nr.: HY-W021425
CAS. Nr.: 5505-63-5
Synonyms: (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride
Target:
1
1 Cited Publications
Art. -Nr.: HY-76948
CAS. Nr.: 865479-71-6
Target:
Forschungsgebiete:
5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM).
1
1 Cited Publications
Art. -Nr.: HY-N2185
CAS. Nr.: 87095-74-7
Synonyms: (5R)-trans-1,7-diphenyl-5-hydroxy-6-hepten-3-one
Category:
Natural Products Alpinia katsumadai Hayata Plants Disease Research Fields Inflammation/Immunology Zingiberaceae
Target:
1
1 Cited Publications
Art. -Nr.: HY-P9923A
CAS. Nr.: 1044511-01-4
Synonyms: MEDI-563 (anti-IL5RA ); BIW-8405 (anti-IL5RA )
Target:
Forschungsgebiete:
1
1 Cited Publications
Target:
Forschungsgebiete:
PCSK9-IN-11 (compound 5r) is a potent and orally active PCSK9 inhibitor. PCSK9-IN-11 exhibits PCSK9 transcriptional inhibitory activity in HepG2 cells, with an IC50 of 5.7 μM. PCSK9-IN-11 increases LDL receptor (LDLR) protein level. PCSK9-IN-11 can be used for atherosclerosis research .
1
1 Cited Publications
Target:
Forschungsgebiete:
(R)-mchm5U is a diastereomer of (S)-mchm5U (HY-153100A) .
1
Target:
Forschungsgebiete:
CYM50308 (ML248) is a potent, selective and high affinity sphingosine-1-phosphate receptor 4 (S1P4-R) agonist with an EC50 of 56 nM. CYM50308 displays 37-fold more selective for S1P4-R than S1P5-R. CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM .
1
1 Cited Publications
Target:
Forschungsgebiete:
THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R), with high affinity and potency for hMC4R (IC50=1.2 nM, EC50=2.1 nM) and rMC4R (IC50=0.6 nM, EC50=2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants .
1
1 Cited Publications
HIV-1 inhibitor-6 (compound 9), a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor. HIV-1 inhibitor-6 blocks HIV replication. HIV-1 inhibitor-6 is active against wild-type HIV-1IIIB (subtype B, X4-tropic) and HIV-1 97USSN54 (subtype A, R5-tropic) with EC50s of 0.6 μM and 0.9 μM, respectively. HIV-1 inhibitor-6 inhibits HIV strains resistant to agents targeting HIV reverse transcriptase, protease, integrase, and coreceptor CCR5 with EC50s ranging from 0.9 to 1.5 μM .
Target:
Forschungsgebiete:
BMS-470539 dihydrochloride is a highly potent and selective melanocortin-1 receptor (MC-1R) agonist with an IC50 of 120 nM, an EC50 of 28 nM. BMS-470539 dihydrochloride does not activate MC-3R and is a very weak partial agonist at MC-4R and MC-5R. BMS-470539 dihydrochloride has potently anti-inflammatory properties .
Art. -Nr.: HY-34550A
CAS. Nr.: 1932042-59-5
Target:
Forschungsgebiete:
tert-Butyl (1S,4S,5R)-5-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate is a pharmaceutical intermediate used to synthesize various active compounds, such as FXR receptor agonists.
Synonyms: PG 701; LLDT-8; 5α-Hydroxytriptolide
Target:
Forschungsgebiete:
(5R)-5-Hydroxytriptolide is an extracted compound from Tripterygium, and shows lower cell cytotoxicity and higher immunosuppressive activity. (5R)-5-Hydroxytriptolide can be used for study of rheumatoid arthritis .
Art. -Nr.: HY-79858
CAS. Nr.: 1192651-49-2
Synonyms: Avibactam sodium intermediate
Target:
Forschungsgebiete:
(2S,5R)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide (Avibactam sodium intermediate) is a drug intermediate for synthesis of various active compounds.
Art. -Nr.: HY-I0909
CAS. Nr.: 170985-86-1
Synonyms: 4-[4-[4-[4-[[(3r,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2s,3s)-2-phenylmethoxypentan-3-yl]-1,2,4-triazol-3-one
Target:
Forschungsgebiete:
O-Benzyl posaconazole (4-[4-[4-[4-[[(3r,5r)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2s,3s)-2-phenylmethoxypentan-3-yl]-1,2,4-triazol-3-one) is a drug intermediate for synthesis of various active compounds.
Art. -Nr.: HY-113025A
CAS. Nr.: 172213-74-0
Synonyms: (2S,5R)-5-Hydroxylysine dihydrochloride
Target:
Art. -Nr.: HY-135383A
CAS. Nr.: 254452-88-5
Target:
Forschungsgebiete:
(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin Calcium (HY-B0144). Pitavastatin is a potent HMG-CoA reductase inhibitor .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
