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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
5hmC
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "5hmC" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-W008091
CAS No.: 554-01-8
2
2 Cited Publications
Cat. No.: HY-W008091R
CAS No.: 554-01-8
2
2 Cited Publications
Cat. No.: HY-W008091A
CAS No.: 58366-64-6
Research Areas:
5-Methylcytosine hydrochloride is a well-characterized DNA modification in prokaryotes and eukaryotes. 5-Methylcytosine hydrochloride forms symmetrical methylation on CpG dinucleotides in DNA, stabilizes tRNA/rRNA structure in RNA, and affects mRNA translation. 5-Methylcytosine hydrochloride can be oxidized to generate 5hmC, 5fC, and 5caC. 5-Methylcytosine hydrochloride can be used in epigenetics, developmental biology, and the study of diseases such as colorectal cancer and hepatocellular carcinoma .
1
1 Cited Publications
Target:
Research Areas:
NSC-370284 is a selective inhibitor of ten-eleven translocation 1 (TET1) and 5-hydroxymethylcytosine (5hmC). NSC-370284 significantly inhibits the level of TET1 expression via targets STAT3/5 .
1
1 Cited Publications
Cat. No.: HY-160638
CAS No.: 73768-68-0
Target:
Research Areas:
NSC-311068 is TET1 inhibitor. NSC-311068 selectively suppress TET1 transcription and 5-hydroxymethylcytosine (5hmC) modification. NSC-311068 represses the level of TET1 expression and the global 5hmC level. NSC-311068 effectively inhibits cell viability in AML cells with high expression of TET1 .
Cat. No.: HY-W018324
CAS No.: 1123-95-1
Synonyms: 5hmC
Target:
Cat. No.: HY-W008091S
CAS No.: 1219795-15-9
Cat. No.: HY-134902
CAS No.: 537039-67-1
Synonyms: UDP-α-6N3-glucose; 6-Azidoglucose-UDP
Target:
Research Areas:
UDP-6-azido-6-Deoxy-D-Glc (UDP-α-6N3-glucose) is a nucleotide sugar. UDP-α-6 N3-glucoside can be used in the selective labeling of 5-hmC in genomic DNA .
Cat. No.: HY-W018324S
Synonyms: 5hmC-13C,d2
Cat. No.: HY-E70583
Target:
Research Areas:
Recombinant Ten-Eleven Translocase is a recombinant Fe(II)- and α-ketoglutarate-dependent dioxygenase. Recombinant Ten-Eleven Translocase converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), and then to 5-formylcytosine (5fC) and 5-carboxycytosine (5caC) through a series of oxidation reactions. Then, 5caC is further converted into uracil (U) through the action of a conversion agent or enzyme, and uracil (U) is converted into thymine (T) through PCR, thereby achieving single-base resolution and high-accuracy identification of DNA methylation sites .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
