3 Results for "

ATLL

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "ATLL" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99253
CAS No.: 1159266-37-1
Synonyms: KW-0761

Target:  

CCR

Research Areas:  

Inflammation/Immunology Cancer

Mogamulizumab (KW-0761) is a recombinant anti-CCR4 monoclonal antibody (MAb). Mogamulizumab can eliminate tumor cells by antibody-dependent cellular cytotoxicity (ADCC). Mogamulizumab can be used in the research of cancers, adult T-cell leukemia/lymphoma (ATLL), cutaneous T-cell lymphoma (CTCL) .
loading...
    loading...
Cat. No.: HY-P991381
Synonyms: PPMX-T003; TSP-A18
JST‑TfR09 (PPMX‑T003) is a human monoclonal antibody (mAb) targeting transferrin receptor 1 (TfR1/CD71). JST‑TfR09 blocks the binding of transferrin to TfR1, inhibits TfR1 internalization, and suppresses cellular iron uptake. JST‑TfR09 triggers ferritin degradation via activating the autolysosomal system, promotes ROS production and lipid peroxidation, and ultimately induces ferroptosis. JST‑TfR09 exhibits cytotoxicity toward human erythroblasts differentiated from hematopoietic stem cells. JST-TfR09 can be used in leukemia research. Recommended isotype control: Human IgG1 lambda, Isotype Control (HY-P99992) .
loading...
    loading...
Cat. No.: HY-P11784
CAS No.: 1423724-82-6
Target:  

Peptides

Research Areas:  

Others

p5RHH is an acid-activated membrane-lytic peptide derived from melittin. p5RHH, as a siRNA delivery vector, initiates synchronous disassembly of nanocomplexes and endosome lysis in response to acidic pH, and triggers the release of siRNA into the cytoplasm following macropinocytosis .
loading...
    loading...