36 Results for "

Antimutagenic activity

" in MedChemExpress (MCE) Product Catalog:
Products (36)

36 Results for "Antimutagenic activity" in MCE Product Catalog:

16
Isochlorogenic acid A
Isochlorogenic acid A
0 Images
16 Publications Verification
Cat. No.: HY-N0056
CAS No.: 2450-53-5
Synonyms: 3,5-Dicaffeoylquinic acid; 3,5-CQA
Category:  

Caprifoliaceae Lonicera japonica Thunb. Ketones, Aldehydes, Acids Phenols Polyphenols Plants Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Free Radical Scavengers Reactive Oxygen Species (ROS) HBV Endogenous Metabolite HIV Bacterial

Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with anti-mutagenicity, anti-HBV, anti-HIV, anti-oxidant, anti-bacterial, and anti-inflammatoryy activities .
loading...
    loading...
View All Sizes
6
Lupeol
Lupeol
0 Images
6 Cited Publications
Cat. No.: HY-N0790
CAS No.: 545-47-1
Synonyms: Clerodol; Monogynol B; Fagarasterol
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Cancer

Target:  

Androgen Receptor Apoptosis

Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent androgen receptor (AR) inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC) .
loading...
    loading...
View All Sizes
2
Zerumbone
Zerumbone
0 Images
2 Cited Publications
Cat. No.: HY-N7015
CAS No.: 471-05-6
Category:  

Infection Zingiber zerumbet Terpenoids Sesquiterpenes Plants Disease Research Fields Zingiberaceae

Target:  

EBV Caspase Apoptosis Bacterial

Zerumbone is an orally active natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet. Zerumbone has anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity .
loading...
    loading...
View All Sizes
2
AV-153 free base
AV-153 free base
0 Images
2 Cited Publications
Cat. No.: HY-135218A
CAS No.: 19350-66-4
Purity:  99.65%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity .
loading...
    loading...
View All Sizes
1
Euphol
Euphol
0 Images
1 Cited Publications
Cat. No.: HY-N0313
CAS No.: 514-47-6
Category:  

Triterpenes Terpenoids Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

MAGL Endogenous Metabolite

Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .
loading...
    loading...
View All Sizes
1
p-Coumaric acid-d6
p-Coumaric acid-d6
0 Images
1 Cited Publications
Cat. No.: HY-N0351S1
CAS No.: 2708298-33-1
Synonyms: trans-4-Hydroxycinnamic acid-d6
p-Coumaric acid-d6 is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities .
loading...
    loading...
View All Sizes
1
Peonidin chloride
Peonidin chloride
0 Images
1 Cited Publications
Cat. No.: HY-N2459
CAS No.: 134-01-0
Synonyms: YGM-6 chloride
Category:  

Plants Food Research Anthocyans Flavonoids Paeonia lactiflora Pall. Pigments Phenols Polyphenols Paeoniaceae Disease Research Fields Cancer

Target:  

Interleukin Related

Peonidin (YGM-6) chloride is an anthocyanin compound found in plants such as grapes and purple-fleshed sweet potatoes. Peonidin chloride alone exerts no stable inhibitory effect on LPS (HY-D1056)-mediated inflammatory gene expression. The acylated form of Peonidin chloride exhibits antimutagenic activity .
loading...
    loading...
View All Sizes
1
(+)-Camphor
(+)-Camphor
0 Images
1 Cited Publications
Cat. No.: HY-B1173
CAS No.: 464-49-3
Synonyms: D-(+)-Camphor; (1R)-(+)-Camphor
Category:  

Other Monoterpenes Terpenoids Other Diseases Plants Lauraceae Disease Research Fields Cinnamomum camphora

Target:  

Environmental Pollutants Bacterial

(+)-Camphor (D-(+)-Camphor; (1R)-(+)-Camphor) is an isomer of Camphor. Camphor is an agonist of monoterpenoid transient receptor potential (TRP) channels (such as TRPV1, TRPV3, TRPM8) and an inhibitor of TRPA1 channels. Camphor's derivatives have multiple biological activities, including antibacterial, antiviral, antioxidant, analgesic and anticancer. Camphor can selectively activate cold-sensitive TRP channels and inhibit TRPA1-mediated nociceptive signals. Camphor stimulates the cold-sensing nerve endings in the skin and regulates the activity of ion channels to exert analgesic, anti-inflammatory and anti-itching effects. It also has anti-proliferative and anti-mutagenic activities on tumor cells, which may be related to inhibiting ribosome function or inducing cell apoptosis. Camphor can be absorbed through the skin and (+)-Camphor can be used in the study of muscle and joint pain and inflammation .
loading...
    loading...
View All Sizes
Garbanzol
Garbanzol
0 Images
Cat. No.: HY-N3926
CAS No.: 1226-22-8
Category:  

Flavanonols Flavonoids Plants Anacardiaceae Toxicodendron vernicifluum (Stokes) F. A. Barkl.

Target:  

Drug Intermediate

Garbanzol is an orally active natural flavonoid compound. Garbanzol is one of the key intermediates in the flavonoid biosynthetic pathway. Garbanzol exhibits anti-mutagenic activity .
loading...
    loading...
View All Sizes
2,6-Dimethoxy-1,4-benzoquinone
2,6-Dimethoxy-1,4-benzoquinone
0 Images
Cat. No.: HY-N1677
CAS No.: 530-55-2
Category:  

Infection Quinones other families Metabolic Disease Benzene Quinones Plants Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Akt mTOR Bacterial Fungal AMPK

2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H2O2 generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness .
loading...
    loading...
View All Sizes
α-Hexylcinnamaldehyde
α-Hexylcinnamaldehyde
0 Images
Cat. No.: HY-W014118
CAS No.: 101-86-0
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Cancer

Target:  

Environmental Pollutants

α-Hexylcinnamaldehyde is an O-acetyltransferase (OAT) inhibitor. α-Hexylcinnamaldehyde inhibits OAT-mediated bioactivation of nitroarene mutagens, exerts antimutagenic activity through demutagenic and bioantimutagenic mechanisms, and interferes with ATP-binding cassette (ABC) transporter function to reduce substrate efflux. α-Hexylcinnamaldehyde alters membrane permeability, fluidizes phospholipid membranes, exerts antioxidant effects, and enhances the antiproliferative effect of Doxorubicin on human cancer cells. α-Hexylcinnamaldehyde can be used in the research of colorectal adenocarcinoma, T-cell leukemia, and multidrug-resistant cancers .
loading...
    loading...
View All Sizes
Biflorin
Biflorin
0 Images
Cat. No.: HY-119956
CAS No.: 89701-85-9
Purity:  99.54%
Category:  

Aegilops triuncialis L. Gramineae Plants Saccharides Monosaccharides

Target:  

Apoptosis STAT

Biflorin has antimicrobial, antitumor, antiinflammatory and antimutagenic activities. Biflorin is found in the roots of Capraria biflora L .
loading...
    loading...
View All Sizes
p-Coumaric acid-13C3
p-Coumaric acid-13C3
0 Images
Cat. No.: HY-N0351S
CAS No.: 1261170-80-2
p-Coumaric acid- 13C3 is the 13C-labeled p-Coumaric acid. p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities.
loading...
    loading...
View All Sizes
4-Decanol
4-Decanol
0 Images
Cat. No.: HY-W275553
CAS No.: 2051-31-2
Category:  

Natural Products Capillipedium parviflorum (R. Br.) Stapf Gramineae Plants

Target:  

DNA Alkylator/Crosslinker

4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of Aflatoxin B1 (HY-N6615) and MNNG (HY-128612) in Salmonella typhimurium TA100 .
loading...
    loading...
View All Sizes
Licoisoflavone B
Licoisoflavone B
0 Images
Cat. No.: HY-N3388
CAS No.: 66056-30-2
Category:  

Flavonoids Leguminosae Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones

Target:  

Stearoyl-CoA Desaturase (SCD)

Licoisoflavone B is an orally active flavonoid found in licorice. Licoisoflavone B alleviates psoriasis via SCD1-targeted lipid metabolism reprogramming and suppression of Th17/IL-17-mediated inflammation. Licoisoflavone B inhiibits superoxide anion generation and superoxide anion-induced lipid peroxidation. Licoisoflavone B binds tightly to Lassa virus nucleoprotein and can be used as a nucleoprotein antagonist of Lassa virus. Licoisoflavone B exhibits anti-mutagenic activity
against carcinogenic mutagen, by preventing DNA damage. Licoisoflavone B can be used for the research of psoriasis, Lassa fever, inflammation and cancer .
loading...
    loading...
View All Sizes
Zerumbone (Standard)
Zerumbone (Standard)
0 Images
Cat. No.: HY-N7015R
CAS No.: 471-05-6
Category:  

Natural Products Zingiber zerumbet Plants Zingiberaceae

Target:  

EBV Reference Standards Caspase Apoptosis Bacterial

Zerumbone (Standard) is the analytical standard of Zerumbone. This product is intended for research and analytical applications. Zerumbone is an orally active natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet. Zerumbone has anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity .
loading...
    loading...
View All Sizes
Euphol (Standard)
Euphol (Standard)
0 Images
Cat. No.: HY-N0313R
CAS No.: 514-47-6
Category:  

Triterpenes Terpenoids Euphorbiaceae Plants

Target:  

MAGL Endogenous Metabolite Reference Standards

Euphol (Standard) is the analytical standard of Euphol. This product is intended for research and analytical applications. Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .
loading...
    loading...
View All Sizes
4-Methylsyringol
4-Methylsyringol
0 Images
Cat. No.: HY-W100715
CAS No.: 6638-05-7
Category:  

Davalliaceae Davallia trichomanoides Blume Plants

Target:  

Others

4-Methylsyringol is a phenolic syringol derivative found in a variety of plants. Phenolic compounds are widely present in food and plants and have high synthetic, medicinal, and industrial value. Polyphenols are compounds with various phenolic functions. Natural polyphenols can regulate the cell cycle, induce apoptosis, inhibit cell adhesion, migration, proliferation, and differentiation, and possess a variety of biological activities such as antioxidation, anti-inflammation, anticancer, and antimutagenic effects .
loading...
    loading...
View All Sizes
(-)-Byakangelicin
(-)-Byakangelicin
0 Images
Cat. No.: HY-N16528
CAS No.: 23517-02-4
Category:  

Xanthones Citrus limon (L.) Burm. F. Rutaceae Phenols Plants

Target:  

Others

(-)-Byakangelicin (Compound 9) is a furanocoumarin compound found in the peels of Citrus limon. (-)-Byakangelicin has antimutagenic activity for Trp-P-1 and PhIP and can be used for the research of cancer .
loading...
    loading...
View All Sizes
Isochlorogenic acid A (Standard)
Isochlorogenic acid A (Standard)
0 Images
Cat. No.: HY-N0056R
CAS No.: 2450-53-5
Synonyms: 3,5-Dicaffeoylquinic acid (Standard); 3,5-CQA (Standard)
Category:  

Caprifoliaceae Lonicera japonica Thunb. Ketones, Aldehydes, Acids Phenols Polyphenols Plants Endogenous metabolite

Target:  

Reference Standards Reactive Oxygen Species (ROS) HBV Endogenous Metabolite HIV Bacterial

Isochlorogenic acid A (Standard) is the analytical standard of Isochlorogenic acid A. This product is intended for research and analytical applications. Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with anti-mutagenicity, anti-HBV, anti-HIV, anti-oxidant, anti-bacterial, and anti-inflammatoryy activities .
loading...
    loading...
View All Sizes
Assay Types