66056-30-2
Chemical Structure
Licoisoflavone B
- CAS No.: 66056-30-2
- Formula:C20H16O6
- Molecular Weight:352.34
IUPAC Name: 5,5',7-trihydroxy-2',2'-dimethyl-2'H,4H-[3,6'-bichromen]-4-one
InChIKey: KIZPADOTOCPASX-UHFFFAOYSA-N
SMILES: OC1=C(C=CC(C)(C)O2)C2=CC=C1C3=COC4=CC(O)=CC(O)=C4C3=O
Biological Activity:
Licoisoflavone B is an orally active flavonoid found in licorice. Licoisoflavone B alleviates psoriasis via SCD1-targeted lipid metabolism reprogramming and suppression of Th17/IL-17-mediated inflammation. Licoisoflavone B inhiibits superoxide anion generation and superoxide anion-induced lipid peroxidation. Licoisoflavone B binds tightly to Lassa virus nucleoprotein and can be used as a nucleoprotein antagonist of Lassa virus. Licoisoflavone B exhibits anti-mutagenic activity
against carcinogenic mutagen, by preventing DNA damage. Licoisoflavone B can be used for the research of psoriasis, Lassa fever, inflammation and cancer[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Licoisoflavone B | 99.46% | Licoisoflavone B is an orally active flavonoid found in licorice. Licoisoflavone B alleviates psoriasis via SCD1-targeted lipid metabolism reprogramming and suppression of Th17/IL-17-mediated inflammation. Licoisoflavone B inhiibits superoxide anion generation and superoxide anion-induced lipid peroxidation. Licoisoflavone B binds tightly to Lassa virus nucleoprotein and can be used as a nucleoprotein antagonist of Lassa virus. Licoisoflavone B exhibits anti-mutagenic activity against carcinogenic mutagen, by preventing DNA damage. Licoisoflavone B can be used for the research of psoriasis, Lassa fever, inflammation and cancer. |
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References
- [1]. Liu Y, et al. Licoisoflavone B alleviates psoriasis via SCD1-targeted lipid metabolism reprogramming and suppression of Th17/IL-17-mediated inflammation. Front Pharmacol. 2026;17:1754729. Published 2026 Feb 16. [Content Brief]
- [2]. Toda S, et al. Inhibitory effects of isoflavones in Sophora mooracrotiana on lipid peroxidation by superoxide[J]. Pharmaceutical biology, 2002, 40(6): 422-424.
- [3]. Faisal Ahmed S, et al. Licoisoflavone B and glabridin from Glycyrrhiza glabra as potent nucleoprotein antagonists of Lassa virus: insights from molecular docking, dynamics simulation, PCA, and DFT studies. J Genet Eng Biotechnol. 2025;23(3):100544. [Content Brief]
- [4]. Vijayalakshmi U, et al. Yeast extract-mediated elicitation of anti-cancerous compounds licoisoflavone B, licochalcone A, and liquirtigenin in callus cultures of Glycyrrhiza glabra[J]. BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology, 2019, 100(4).
