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Results for "

B-cell lymphoma 6

" in MedChemExpress (MCE) Product Catalog:

By Targets:	BCL6 (3) Apoptosis (1) Autophagy (1) Bcl-2 Family (10) E3 Ligase Ligand-Linker Conjugates (1) Molecular Glues (1) PROTACs (1)
By Research Areas:	Cancer (14) Inflammation/Immunology (1)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Antibodies

Targets Recommended: BCL6 Anaplastic lymphoma kinase (ALK) MALT1

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-129188

CCT369260	Bcl-2 Family Molecular Glues	Cancer
CCT369260 (compound 1), a chemical probe, is an orally avtive B-cell lymphoma 6 (BCL6) inhibitor with anti-tumor activity. CCT369260 (compound 1) exhibits an IC₅₀ of 520 nM .

HY-122829

BCL6 PROTAC 1	PROTACs BCL6	Cancer
BCL6 PROTAC 1 is a selective **B-cell lymphoma 6 (BCL6) PROTAC*. BCL6 PROTAC 1 inhibits BCL6 cell* reporter with an IC₅₀ value of 8.8 µM. BCL6 PROTAC 1 significantly degrades BCL6 in diffuse large B-cell lymphoma (DLBCL) cell lines. BCL6 PROTAC 1 can be used in tumor related research .

HY-143653

BCL6-IN-6	BCL6	Cancer
BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL) .

HY-148281

TMX-2164	Bcl-2 Family	Cancer
TMX-2164 is a potent, irreversible B-cell lymphoma 6 (BCL6) inhibitor with an IC₅₀ value of 152 nM. TMX-2164 displays sustained target engagement and antiproliferative activity in cells .

HY-148631

GSK137	BCL6	Inflammation/Immunology Cancer
GSK137 is an orally active, potent and selective B-cell lymphoma 6 (BCL6) inhibitor. GSK137 blocks the interaction between BCL6 and corepressors (e.g., SMRT), reducing the number of germinal center B cells. GSK137 is promising for research of autoimmune diseases such as systemic lupus erythematosus (SLE) and B-cell-related tumors such as diffuse large B-cell lymphoma .

HY-119402

TP-021 1 Publications Verification BCL6-IN-8c	Bcl-2 Family	Cancer
TP-021 (BCL6-IN-8c), a chemical probe, is a potent and orally active B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor with an IC₅₀ of 0.10 μM in cell-free enzyme-linked immunosorbent assay .

HY-134982

Thalidomide-piperazine-Boc	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-piperazine-Boc is an intermediate that can be used in the synthesis of B-cell lymphoma 6 protein (BCL6) PROTAC .

HY-136640

BCL6-IN-4	Bcl-2 Family	Cancer
BCL6-IN-4 is a potent B-cell lymphoma 6 (BCL6) inhibitor with an IC₅₀ of 97 nM. BCL6-IN-4 has anti-tumor activities .

HY-146183

BCL6-IN-9	Bcl-2 Family	Cancer
BCL6-IN-9 (compound 1) is a potent B-cell lymphoma 6 protein (BCL6) inhibitor, with an IC₅₀ of 3.9 nM. BCL6-IN-9 can be used for the research of cancer .

HY-153096

OICR12694 JNJ-65234637	Bcl-2 Family	Cancer
OICR12694 (JNJ-65234637) is an orally active inhibitor of B cell lymphoma 6 (BCL6) .

HY-153096A

OICR12694 TFA JNJ-65234637 TFA	Bcl-2 Family	Cancer
OICR12694 (JNJ-65234637) TFA is an orally active inhibitor of B cell lymphoma 6 (BCL6) .

HY-100866B

F1324 acetate	Bcl-2 Family	Cancer
F1324 acetate is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC₅₀ of 1 nM. F1324 acetate exhibits binding t_1/2 value of 441 s and has strong inhibition activity against BCL6 PPI .

HY-100866

F1324	Bcl-2 Family	Cancer
F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC₅₀ of 1 nM. F1324 exhibits binding t_1/2 value of 441 s and has strong inhibition activity against BCL6 PPI .

HY-100866A

F1324 TFA	Bcl-2 Family	Cancer
F1324 TFA is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC₅₀ of 1 nM. F1324 TFA exhibits binding t_1/2 value of 441 s and has strong inhibition activity against BCL6 PPI .

Cat. No.	상품명	Target	Research Area

HY-100866B

F1324 acetate	Bcl-2 Family	Cancer
F1324 acetate is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC₅₀ of 1 nM. F1324 acetate exhibits binding t_1/2 value of 441 s and has strong inhibition activity against BCL6 PPI .

HY-100866

F1324	Bcl-2 Family	Cancer
F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC₅₀ of 1 nM. F1324 exhibits binding t_1/2 value of 441 s and has strong inhibition activity against BCL6 PPI .

HY-100866A

F1324 TFA	Bcl-2 Family	Cancer
F1324 TFA is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC₅₀ of 1 nM. F1324 TFA exhibits binding t_1/2 value of 441 s and has strong inhibition activity against BCL6 PPI .

Species:	Human (2)
Tag:	Tag Free (1) GST (1)
Source:	E. coli (2)

Cat. No.	Compare	상품명	Species	Source	Image

HY-P702575

	BCL6 Protein, Human B cell CLL/lymphoma 6; B cell lymphoma 6 protein; B-cell lymphoma 5 protein; B-cell lymphoma 6 protein; BCL 5; Bcl 6; BCL-5; BCL-6; BCL5; BCL6; BCL6_HUMAN; BCL6A; Protein LAZ-3; ZBTB 27; ZBTB27; Zinc finger protein 51; zinc finger transcription factor BCL6S; ZNF 51; ZNF51	Human	E. coli
	BCL6 is a key transcriptional repressor of germinal centers and regulates multiple biological functions and lineages. It forms a complex with corepressors and histone deacetylase, directly binds to 5'-TTCCTAGAA-3', and inhibits genes involved in differentiation, inflammation, apoptosis and cell cycle control in GC B cells. BCL6 Protein, Human is the recombinant human-derived BCL6 protein, expressed by E. coli , with tag free.

HY-P72102

	BCL6 Protein, Human (GST) B cell CLL/lymphoma 6; B cell lymphoma 6 protein; B-cell lymphoma 5 protein; B-cell lymphoma 6 protein; BCL 5; Bcl 6; BCL-5; BCL-6; BCL5; BCL6; BCL6_HUMAN; BCL6A; Protein LAZ-3; ZBTB 27; ZBTB27; Zinc finger protein 51; zinc finger transcription factor BCL6S; ZNF 51; ZNF51	Human	E. coli
	BCL6 is a key transcriptional repressor of germinal centers and regulates multiple biological functions and lineages. It forms a complex with corepressors and histone deacetylase, directly binds to 5'-TTCCTAGAA-3', and inhibits genes involved in differentiation, inflammation, apoptosis and cell cycle control in GC B cells. BCL6 Protein, Human (GST) is the recombinant human-derived BCL6 protein, expressed by E. coli , with N-GST labeled tag.

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Tag
Accession
Gene ID
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Host:	Mouse (1) Rabbit (2)
Reactivity:	Human (3) Mouse (1)
Application:	IHC-P (2) ICC/IF (1) WB (1) ELISA (1)
Isotype:	IgG3 (1) IgG (2)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	상품명	Application	Reactivity	Image

HY-P81536

	Bcl-6 Antibody (YA1281) BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51	IHC-P	Human
	Bcl-6 Antibody (YA1281) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Bcl-6.

HY-P85808

	Bcl-6 Antibody (YA5500) BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51	WB, ICC/IF, ELISA	Human, Mouse
	Bcl-6 Antibody (YA5500) is a Mouse-derived and non-conjugated IgG3 monoclonal antibody, targeting to Bcl-6.

HY-P81536A

	Bcl-6 Antibody (YA1281)(PBS only) BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51	IHC-P	Human
	Bcl-6 Antibody (YA1281) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Bcl-6.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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