BCL6-IN-9
BCL6-IN-9 (compound 1) is a potent B-cell lymphoma 6 protein (BCL6) inhibitor, with an IC50 of 3.9 nM. BCL6-IN-9 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 2378852-76-5
- Formula: C22H18ClF2N5O2
- Molecular Weight:457.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 3.9 nM (B-cell lymphoma 6 protein)[1]
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| KARPAS-422 | GI50 |
0.19 μM
Compound: 1
|
Antiproliferative activity against human KARPAS-422 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay
Antiproliferative activity against human KARPAS-422 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay
|
[PMID: 35657291] |
| OCI-Ly1 | GI50 |
0.17 μM
Compound: 1
|
Antiproliferative activity against human OCI-Ly1 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay
Antiproliferative activity against human OCI-Ly1 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay
|
[PMID: 35657291] |
| OCI-Ly3 | GI50 |
3.4 μM
Compound: 1
|
Antiproliferative activity against human OCILY3 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay
Antiproliferative activity against human OCILY3 cells assessed as cell growth inhibition mesured after 14 days by CellTiter-Glo luminescent assay
|
[PMID: 35657291] |
Chemical Information
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CAS No. 2378852-76-5
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Molecular Weight 457.86
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Formula C22H18ClF2N5O2
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SMILES
N#CC1=C(NC2=CC3=C(N(C)C(C4=C3N[C@@H](C5CC5)C(F)(F)CO4)=O)C=C2)C=CN=C1Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)