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Isoforms Recommended:	CCR9

Results for "

CCR9

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CCR (11) E1/E2/E3 Enzyme (1) Endogenous Metabolite (1) Ligands for Target Protein for PROTAC (1) mRNA (1) PROTACs (1) RAR/RXR (1) Reference Standards (2) Small Interfering RNA (siRNA) (5) Target Protein Ligand-Linker Conjugates (1)
By Research Areas:	Cancer (1) Endocrinology (4) Inflammation/Immunology (10) Metabolic Disease (1)
Oligonucleotides:	Chemokine & Receptors (1) Rat Pre-designed siRNA Sets (1) mRNA (1) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (2) siRNAs (5)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: CCR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15724

Vercirnon 3 Publications Verification GSK-1605786; CCX282-B; Traficet-EN	CCR Ligands for Target Protein for PROTAC	Inflammation/Immunology Endocrinology
Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of *CCR9. Vercirnon inhibits CCR9-mediated* Ca ²⁺ mobilization and chemotaxis on Molt-4 cells with IC₅₀ values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC₅₀s>10 μM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC₅₀ values of 2.8 and 2.6 nM, respectively .

HY-123763

MLN3126	CCR	Inflammation/Immunology
MLN3126 is an orally active and potent *CCR9* antagonist. MLN3126 inhibits CCL25-induced calcium mobilization and chemotaxis of mouse primary thymocytes, wiht an IC₅₀ value of 6.3 nM for calcium influx .

HY-15724A

Vercirnon sodium 3 Publications Verification GSK-1605786 sodium; CCX282-B sodium; Traficet-EN sodium	CCR	Inflammation/Immunology Endocrinology
Vercirnon (GSK1605786A) sodium is an orally bioavailable, selective, and potent antagonist of *CCR9. Vercirnon sodium inhibits CCR9-mediated* Ca ²⁺ mobilization and chemotaxis on Molt-4 cells with IC₅₀ values of 5.4 and 3.4 nM, respectively. Vercirnon sodium is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC₅₀s>10 μM for all). Vercirnon sodium is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC₅₀ values of 2.8 and 2.6 nM, respectively .

HY-117545

LE-540	RAR/RXR	Cancer
LE-540 is a selective retinoic acid receptor antagonist for RARβ (K_i=0.22 μM). LE-540 shows potential for use in cancer research, particularly for breast cancer and lung cancer .

HY-RS02174

Ccr9 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ccr9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccr9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccr9 Rat Pre-designed siRNA Set A Ccr9 Rat Pre-designed siRNA Set A

HY-RS02173

Ccr9 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA) CCR	Others
Ccr9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccr9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccr9 Mouse Pre-designed siRNA Set A Ccr9 Mouse Pre-designed siRNA Set A

HY-RS02172

CCR9 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) CCR	Others
CCR9 Human Pre-designed siRNA Set A contains three designed siRNAs for CCR9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CCR9 Human Pre-designed siRNA Set A CCR9 Human Pre-designed siRNA Set A

HY-181287

*PROTAC CCR9* Degrader 1**	PROTACs CCR E1/E2/E3 Enzyme	Inflammation/Immunology
PROTAC CCR9 Degrader 1 is a PROTAC-based degrader targeting *CCR9. PROTAC CCR9* Degrader 1 induces ubiquitination, proteasomal degradation of CCR9 and reduces intracellular CCR9 levels by recruiting the VHL E3 ligase. PROTAC CCR9 Degrader 1 has a K_i value of 78.0 nM against human *CCR9. PROTAC CCR9* Degrader 1 modulates GPCR activity by binding to the intracellular allosteric binding site of *CCR9. PROTAC CCR9* Degrader 1 can be used in research related to Crohn's disease .

HY-186003

CCR9 modulator-1	CCR	Inflammation/Immunology
CCR9 modulator-1 (example 16) is a *CCR9* modulator.

HY-174740

*Human CCR9* mRNA**	mRNA	Inflammation/Immunology
Human CCR9 mRNA encodes the human C-C motif chemokine receptor 9 (CCR9) protein, a member of the beta chemokine receptor family. CCR9 plays a role in directing immune responses to different segments of the gastrointestinal tract.

HY-181288

CCR9 ligand-Linker Conjugate 1	Target Protein Ligand-Linker Conjugates CCR	Inflammation/Immunology
CCR9 ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate containing a *CCR9* ligand and a PROTAC linker, which recruits E3 ligases. USP7 Ligand-Linker Conjugates 1 can be used to synthesize PROTAC CCR9 Degrader 1 (HY-181287) .

HY-15724R

Vercirnon (Standard) GSK-1605786 (Standard); CCX282-B (Standard); Traficet-EN (Standard)	CCR Reference Standards	Inflammation/Immunology Endocrinology
Vercirnon (Standard) is the analytical standard of Vercirnon. This product is intended for research and analytical applications. Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 μM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively .

HY-15724AR

Vercirnon sodium (Standard) GSK-1605786 sodium (Standard); CCX282-B sodium (Standard); Traficet-EN sodium (Standard)	CCR Reference Standards	Inflammation/Immunology Endocrinology
Vercirnon (sodium) (Standard) is the analytical standard of Vercirnon (sodium). This product is intended for research and analytical applications. Vercirnon (GSK1605786A) sodium is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon sodium inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon sodium is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 μM for all). Vercirnon sodium is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively .

HY-P992199

*Anti-CCR9* Antibody**	CCR	Inflammation/Immunology
Anti-CCR9 Antibody is a monoclonal antibody targeting CCR9. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-CCR9 Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-113545

9(R)-HODE 9(R)-Hydroxyoctadecadienoic acid	Endogenous Metabolite	Metabolic Disease
9(R)-HODE is a monohydroxy fatty acid and metabolite of linoleic acid. It is formed from linoleic acid by COX and lipoxygenase (LO).9(R)-HODE induces chemotaxis, increases the levels of chemokine (C-C motif) receptor 9 (CCR9) and chemokine (C-X-C motif) receptor 4 (CXCR4), and inhibits IL-6 release in primary human monocytes. It inhibits CD3α- and CD28-induced proliferation of isolated human peripheral blood lymphocytes when used at a concentration of 25 μg/mL.

HY-RS00161

ACKR2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ACKR2 Human Pre-designed siRNA Set A contains three designed siRNAs for ACKR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ACKR2 Human Pre-designed siRNA Set A ACKR2 Human Pre-designed siRNA Set A

HY-RS20849

Ackr2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ackr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ackr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ackr2 Mouse Pre-designed siRNA Set A Ackr2 Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area	Image

HY-P992199

*Anti-CCR9* Antibody**	CCR	Inflammation/Immunology
Anti-CCR9 Antibody is a monoclonal antibody targeting CCR9. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-CCR9 Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).

Recombinant Proteins Recommended:

CCR9

Species:	Human (3)
Tag:	His (2) GST (1)
Source:	HEK293 (1) E. coli Cell-free (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P700378

	ACKR2 Protein, Human (Cell-Free, His) ACKR2; atypical chemokine receptor 2; CCBP2; chemokine binding protein 2; CMKBR9; chemokine-binding protein 2; CCR9; CCR10; D6; chemokine receptor D6; chemokine receptor CCR-9; C-C chemokine receptor D6; chemokine receptor CCR-10; chemokine (C-C) receptor 9; chemokine-binding protein D6; chemokine (C-C motif) receptor 9; CC-chemokine-binding receptor JAB61; hD6; MGC126678; MGC138250;	Human	E. coli Cell-free
	The ACKR2 protein is an atypical chemokine receptor that controls chemokine levels and localization through high-affinity binding. ACKR2 (also known as interceptor or decoy receptor) operates independently, interacts with multiple chemokines, and triggers β-arrestin 1-dependent signaling pathways. ACKR2 Protein, Human (Cell-Free, His) is the recombinant human-derived ACKR2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

HY-P700544

	CCR9 Protein, Human (GST) chemokine (C-C motif) receptor 9; GPR28; C-C chemokine receptor type 9; CDw199; GPR 9 6; G protein-coupled receptor 28; GPR-9-6; CC-CKR-9	Human	E. coli
	CCR9 Protein, a receptor for SCYA25/TECK, activates signaling, elevating intracellular calcium ions. In microbial infection, it acts as an alternative HIV-1 coreceptor with CD4, influencing the infection process. CCR9 Protein, Human (GST) is the recombinant human-derived CCR9 protein, expressed by E. coli , with N-GST labeled tag.

HY-P702597

	CCR9 Protein-VLP, Human (HEK293, His) chemokine (C-C motif) receptor 9; GPR28; C-C chemokine receptor type 9; CDw199; GPR 9 6; G protein-coupled receptor 28; GPR-9-6; CC-CKR-9;	Human	HEK293
	CCR9 Protein-VLP, Human (HEK293, His) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P701236. Tags can only be detected under denaturing conditions.

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HY-P83374

	CCR9 Antibody (YA3119) G-protein coupled receptor 28; GPR-9-6; CDw199; CCR9	WB, ICC/IF, FC	Human, Mouse, Rat
	CCR9 Antibody (YA3119) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CCR9.

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Ccr9 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ccr9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccr9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccr9 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ccr9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccr9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

CCR9 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CCR9 Human Pre-designed siRNA Set A contains three designed siRNAs for CCR9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

*Human CCR9* mRNA**		mRNA Chemokine & Receptors
Human CCR9 mRNA encodes the human C-C motif chemokine receptor 9 (CCR9) protein, a member of the beta chemokine receptor family. CCR9 plays a role in directing immune responses to different segments of the gastrointestinal tract.

ACKR2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ACKR2 Human Pre-designed siRNA Set A contains three designed siRNAs for ACKR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ackr2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ackr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ackr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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