16 Results for "

CD146

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "CD146" in MCE Product Catalog:

Cat. No.: HY-RS08215
Research Areas:  

Others

MCAM Human Pre-designed siRNA Set A contains three designed siRNAs for MCAM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P992200
Anti-CD146 Antibody (AA98) is an antibody targeting CD146 and an angiogenesis inhibitor. Anti-CD146 Antibody (AA98) blocks the dimerization of CD146 as well as its downstream PI3K/AKT, p38 MAPK and NF-κB signaling pathways; it inhibits the expression of MMP9 and ICAM1, epithelial-mesenchymal transition (EMT), and the proliferation, migration and tube formation of endothelial cells. Anti-CD146 Antibody (AA98) enhances radiation-induced cancer cell apoptosis and survival inhibition, reduces tumor microvessel density, and suppresses tumor growth, invasion and vasculogenic mimicry. Anti-CD146 Antibody (AA98) can be used in research related to cervical cancer, liver cancer, malignant phyllodes tumor of the breast, uveal melanoma, leiomyosarcoma, pancreatic cancer, other tumors and angiogenesis .
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Cat. No.: HY-P78582
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MCAM; CD146; MUC18
Species:  
Source:  
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Cat. No.: HY-P992430
OI-3 is a monoclonal antibody targeting CD146 (MCAM). OI-3 specifically binds to CD146 on the surface of human mesothelioma cells and undergoes endocytosis; both chimeric (chOI-3) and murine (mOI-3) variants possess this activity. When conjugated with 212Pb to form 212Pb-TCMC-OI-3, OI-3 acts as a cytotoxic agent that delivers α-emitting radionuclides to induce targeted cytotoxicity. OI-3 can be used in research related to malignant peritoneal mesothelioma .
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Cat. No.: HY-P992372

Research Areas:  

Cancer

huAA98 is a humanized monoclonal antibody and also a CD146 inhibitor. huAA98 binds to human CD146, regulates its activity and inhibits cancer-related angiogenesis, as well as tube formation, motility, proliferation and migration of endothelial cells. huAA98 inhibits angiogenesis in the chick chorioallantoic membrane assay and reduces microvessel density in human tumor xenograft models. huAA98 shows immunoreactivity only to neovascular vessels within tumors and inhibits the growth of tumor xenograft models. huAA98 can be used in studies related to cancer-related angiogenesis, liver cancer, leiomyosarcoma and pancreatic cancer .
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Cat. No.: HY-P99658A
Imaprelimab (powder) is a humanized IgG1κ anti-CD146 antibody. Imaprelimab (powder) exerts anti-angiogenic effects on brain metastasis of lung cancer in animal models. Imaprelimab (powder) can be used in studies related to brain metastasis of non-small cell lung cancer .
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Cat. No.: HY-P75611
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cell surface glycoprotein MUC18; CD146; MCAM; MUC18
Species:  
Source:  
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Cat. No.: HY-P75612
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Cell surface glycoprotein MUC18; CD146; MCAM; MUC18
Species:  
Source:  
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Cat. No.: HY-P76201
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cell surface glycoprotein MUC18; Gicerin; CD146; Muc18
Species:  
Source:  
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Cat. No.: HY-P75613
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cell surface glycoprotein MUC18; CD146; MCAM; MUC18
Species:  
Source:  
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Cat. No.: HY-P85790
Synonyms: Cell surface glycoprotein MUC18; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD antigen CD146;

Host:  

Mouse

Application:  

IHC-P, WB, ICC/IF, ELISA

Reactivity:  

Human

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Cat. No.: HY-P86410
Synonyms: Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD antigen CD146)

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P80595
Synonyms: A32 antigen antibody; CD 146 antibody; CD146 antibody; CD146 antigen antibody; Cell surface glycoprotein MUC18 antibody; Cell surface glycoprotein P1H12 antibody; Gicerin antibody; Mcam antibody; Melanoma adhesion molecule antibody; Melanoma associated antigen A32 antibody; Melanoma associated antigen MUC18 antibody; Melanoma associated glycoprotein MUC18 antibody; Melanoma cell adhesion molecule antibody; Melanoma-associated antigen A32 antibody; Melanoma-associated antigen MUC18 antibody; MelCAM antibody; MUC 18 antibody; MUC18 antibody; MUC18_HUMAN antibody; S endo 1 antibody; S endo 1 endothelial associated antigen antibody; S-endo 1 endothelial-associated antigen antibody;

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Rat

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Cat. No.: HY-P80595A
Synonyms: A32 antigen antibody; CD 146 antibody; CD146 antibody; CD146 antigen antibody; Cell surface glycoprotein MUC18 antibody; Cell surface glycoprotein P1H12 antibody; Gicerin antibody; Mcam antibody; Melanoma adhesion molecule antibody; Melanoma associated antigen A32 antibody; Melanoma associated antigen MUC18 antibody; Melanoma associated glycoprotein MUC18 antibody; Melanoma cell adhesion molecule antibody; Melanoma-associated antigen A32 antibody; Melanoma-associated antigen MUC18 antibody; MelCAM antibody; MUC 18 antibody; MUC18 antibody; MUC18_HUMAN antibody; S endo 1 antibody; S endo 1 endothelial associated antigen antibody; S-endo 1 endothelial-associated antigen antibody;

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Rat

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Cat. No.: HY-RS24435
Research Areas:  

Others

Mcam Rat Pre-designed siRNA Set A contains three designed siRNAs for Mcam gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17964
Research Areas:  

Others

Mcam Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mcam gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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