22 Results for "

CD27 Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "CD27 Antibody" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99014
CAS No.: 1864871-20-4
Synonyms: ARGX-110

Research Areas:  

Inflammation/Immunology Cancer

Cusatuzumab (ARGX-110) is a selective competitive blocker targeting CD70 (with an equilibrium dissociation constant of 17 pM for binding to human CD70). Cusatuzumab also possesses enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) activity. It is a humanized IgG1 monoclonal antibody, artificially synthesized through humanization and genetic engineering modifications (CH2 region mutation to enhance effector function). Cusatuzumab has a dual mechanism of action: firstly, it competitively blocks the interaction between CD70 and CD27, inhibiting the CD27-NF-κB signaling pathway, reducing regulatory T cell (Treg) activation and tumor cell proliferation; secondly, by enhancing binding to FcγRIIIa, it mediates ADCC and antibody-dependent cellular phagocytosis (ADCP), directly lysing CD70-positive tumor cells. Cusatuzumab can efficiently eliminate leukemia stem cells (LSCs), induce tumor cell differentiation and apoptosis, restore immune surveillance, and target CD70-positive tumors. Cusatuzumab is used in the study of acute myeloid leukemia (AML) .
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Cat. No.: HY-P99057
CAS No.: 1393344-72-3
Synonyms: CDX-1127
Varlilumab (CDX-1127) is an agonist anti-CD27 monoclonal antibody. Varlilumab can promote T cell expansion and activate the immune response. Varlilumab has anti-tumor activity and can be used in the research of hematological malignancies and solid tumors .
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Cat. No.: HY-P990018
CAS No.: 2444297-08-7
Synonyms: MK-5890

Target:  

TNF Receptor NF-κB

Research Areas:  

Inflammation/Immunology Cancer

Boserolimab (MK-5890) is a humanized agonist monoclonal antibody that binds to CD27 to provide a costimulatory signal that enhances T-cell–mediated responses .
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Cat. No.: HY-P991661
CAS No.: 1607838-85-6
AMG-172 Antibody is an anti-CD27L antibody. AMG-172 Antibody can be used for synthesis of ADC AMG-172 (HY-185483) .
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Cat. No.: HY-P990280
Anti-Mouse CD27 Antibody (RM27-3E5) is an agonistic rat-derived IgG2a κ type antibody, targeting to mouse CD27. Anti-Mouse CD27 Antibody (RM27-3E5) stimulates CD 27. Anti-Mouse CD27 Antibody (RM27-3E5) can be used for the researches of cancer and immunology, such as B16cOVA tumor .
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Cat. No.: HY-P991063
CAS No.: 2733575-82-9
Synonyms: BNT-313; Tixestobart

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

GEN-1053 (BNT-313) is a fully human IgG1 antibody that targets CD27. GEN-1053 binds to CD27 and forms a hexamer upon binding. The isotype control for GEN-1053 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992) .
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Cat. No.: HY-120255
CAS No.: 155976-53-7
Synonyms: 17(R)-HDoHE
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

17(R)-HDHA (17(R)-HDoHE) is a pro-resolving mediator (SPM). 17(R)-HDHA enhances the differentiation of B cells toward the CD27(+)CD38(+) antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells. 17(R)-HDHA does not affect cell proliferation and is non-toxic to cells .
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Cat. No.: HY-P991465

Target:  

TNF Receptor

Research Areas:  

Cancer

Anti-CD27 Antibody (M2177) is a human monoclonal antibody (mAb) targeting TNFRSF7/CD27. Anti-CD27 Antibody (M2177) inhibits the binding of sCD70 to human CD27 ECD-Fc. Anti-CD27 Antibody (M2177) can be used in the study of anti-tumor immunity. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991466

Target:  

TNF Receptor

Research Areas:  

Cancer

Anti-CD27 Antibody (M2191) is a human monoclonal antibody (mAb) targeting TNFRSF7/CD27. Anti-CD27 Antibody (M2191) inhibits the binding of sCD70 to human CD27 ECD-Fc. Anti-CD27 Antibody (M2191) can be used in the study of anti-tumor immunity. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P990528

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Anti-TNFRSF7/CD27 Antibody is a CHO-expressed human antibody targeting TNFRSF7/CD27. The Anti-TNFRSF7/CD27 Antibody contains huIgG2 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-TNFRSF7/CD27 Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P99057A
CAS No.: 1393344-72-3
Synonyms: CDX-1127 (anti-CD27)
Varlilumab (CDX-1127) (anti-CD27) is an agonist anti-CD27 monoclonal antibody. Varlilumab (anti-CD27) can promote T cell expansion and activate the immune response. Varlilumab (anti-CD27) has anti-tumor activity and can be used in the research of hematological malignancies and solid tumors .
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Cat. No.: HY-P84981
Synonyms: CD 27 Antibody; CD27 Antibody; CD27 antigen Antibody; CD27 molecule Antibody; CD27_HUMAN Antibody; CD27L receptor Antibody; LPFS2 Antibody; MGC20393 Antibody; OTTHUMP00000238557 Antibody; S152 Antibody; T cell activation antigen CD27 Antibody; T cell antivation antigen S152 Antibody; T-cell activation antigen CD27 Antibody; T14 Antibody; TNFRSF 7 Antibody; TNFRSF7 Antibody; TNFSF7 Antibody; Tp 55 Antibody; Tp55 Antibody; Tumor necrosis factor receptor superfamily member 7 Antibody; CD27 nanobody;

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P85859
Synonyms: CD 27 Antibody; CD27 Antibody; CD27 antigen Antibody; CD27 molecule Antibody; CD27_HUMAN Antibody; CD27L receptor Antibody; LPFS2 Antibody; MGC20393 Antibody; OTTHUMP00000238557 Antibody; S152 Antibody; T cell activation antigen CD27 Antibody; T cell antivation antigen S152 Antibody; T-cell activation antigen CD27 Antibody; T14 Antibody; TNFRSF 7 Antibody; TNFRSF7 Antibody; TNFSF7 Antibody; Tp 55 Antibody; Tp55 Antibody; Tumor necrosis factor receptor superfamily member 7 Antibody; CD27 nanobody;

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P991809

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD70 Antibody (TAN 1-7) reacts with the mouse CD70. Anti-Mouse CD70 Antibody (TAN 1-7) is a non-depleting antibody which blocks the CD70-CD27 interaction. Recommend Isotype Controls: Rat IgG2a kappa, Isotype Control (HY-P990679).
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Cat. No.: HY-P85815
Synonyms: CD27, TNFRSF7, CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7

Host:  

Mouse

Application:  

WB, ICC/IF, ELISA

Reactivity:  

Human

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Cat. No.: HY-P81533
Synonyms: CD27; CD27L receptor; LPFS2; S152; T14; TNFRSF7; TNFSF7; Tp55

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P81533A
Synonyms: CD27; CD27L receptor; LPFS2; S152; T14; TNFRSF7; TNFSF7; Tp55

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P85005
Synonyms: CD70; CD27L; CD27LG; TNFSF7; CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD antigen CD70; CD70 nanobody;

Host:  

Mouse

Application:  

ELISA, FC

Reactivity:  

Human

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Cat. No.: HY-P81664
Synonyms: CD70; CD27LG; TNFSF7; TNFSF7G; CD27L

Host:  

Rabbit

Application:  

WB, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P88574
Synonyms: CD27BP; SIVA; Siva-1; Siva-2

Host:  

Mouse

Application:  

IHC-P, ICC/IF

Reactivity:  

Human

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