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Results for "

CD276

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CD276/B7-H3 (5) CD47 (1) ADC Antibody (1) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (1) Small Interfering RNA (siRNA) (3) STAT (1)
By Research Areas:	Cancer (6) Inflammation/Immunology (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: CD276/B7-H3 CD1 CD38 CD28 CD19 CD20 CD22 Transferrin Receptor CD3 P-selectin CD6 CD2 CD73 c-Kit LAG-3 L-Selectin CTLA-4 CD47 ALCAM/CD166 Neprilysin E-Selectin Scavenger Receptor Class B type I (SR-BI） FLT3 Tim3 CD44 Anaplastic lymphoma kinase (ALK) CD74 Human leukocyte immunoglobulin (Ig)-like receptors (LILR) P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99740

Mirzotamab	CD276/B7-H3 ADC Antibody	Cancer
Mirzotamab is an IgG1κ monoclonal antibody targeting to *CD276/B7-H3* with anti-tumor activity. Mirzotamab conjugates with Clezutoclax (HY-137774), a BCL inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane research in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted antibody drug conjugate (ADC) .

HY-P99157

Omburtamab	CD276/B7-H3	Cancer
Omburtamab is a humanized monoclonal antibody targeting B7-H3 (CD276). Omburtamab selectively binds to B7-H3 highly expressed on the surface of tumor cells and activates anti-tumor immune responses mediated by T cells and natural killer (NK) cells. Omburtamab can promote the specific infiltration of CAR-T cells into tumors, enhance the killing function of NK cells through the CD16 signaling pathway, and regulate tumor cell glucose metabolism (such as inhibiting the Warburg effect). Omburtamab has the potential to inhibit solid tumors such as non-small cell lung cancer (NSCLC) .

HY-P990279

*Anti-Mouse CD276/B7-H3 Antibody (MJ18)*	CD276/B7-H3 Apoptosis STAT	Inflammation/Immunology Cancer
Anti-Mouse CD276/B7-H3 Antibody (MJ18) is a rat-derived anti-mouse *CD276/B7-H3* IgG1 monoclonal antibody. Anti-Mouse CD276/B7-H3 Antibody (MJ18) can inhibit CD276/B7-H3 and induce tumor cell apoptosis. Anti-Mouse CD276/B7-H3 Antibody (MJ18) enhances anti-tumor immune response by reducing immunosuppressive cells and promoting T cell activation. Anti-Mouse CD276/B7-H3 Antibody (MJ18) can be used for research on cancer such as breast cancer and prostate cancer .

HY-145636

Vobramitamab duocarmazine AEX4089DC1; MGC018	Antibody-Drug Conjugates (ADCs)	Cancer
Vobramitamab duocarmazine (AEX4089DC1; MGC018), a humanized antibody-drug conjugate (ADC) targeted against B7-H3 (CD276). Vobramitamab duocarmazine is comprised of the cleavable linker-Duocarmycin payload, Vc-seco-DUBA (HY-128957), conjugated to an anti-B7-H3 humanized IgG1κ monoclonal antibody. Vobramitamab duocarmazine has antineoplastic activity .

HY-RS17006

Cd276 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cd276 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd276 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cd276 Mouse Pre-designed siRNA Set A Cd276 Mouse Pre-designed siRNA Set A

HY-RS02220

CD276 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CD276 Human Pre-designed siRNA Set A contains three designed siRNAs for CD276 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CD276 Human Pre-designed siRNA Set A CD276 Human Pre-designed siRNA Set A

HY-RS23449

Cd276 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cd276 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd276 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cd276 Rat Pre-designed siRNA Set A Cd276 Rat Pre-designed siRNA Set A

HY-P990340

*Anti-B7-H3/CD276* Antibody**	CD276/B7-H3	Inflammation/Immunology
Anti-B7-H3/CD276 Antibody is a CHO-expressed human antibody targeting *B7-H3/CD276. Anti-B7-H3/CD276* Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-B7-H3/CD276 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992110

Elfetabart DB-1311 Antibody; BNT324 Antibody	CD276/B7-H3	Cancer
Elfetabart is a humanized monoclonal antibody targeting *CD276* with antitumor activity. The antibody isotype of Elfetabart is human IgG1κ, and the recommended isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992158

VBI-009	CD47	Cancer
VBI-009 is a CD47 and B7-H3 (CD276) bispecific antibody. VBI-009 blocks CD47-SIRPα 'don't eat me' signals and restricts activity to CD47 ⁺/B7-H3 ⁺ cells. VBI-009 induces antibody-dependent cellular phagocytosis (ADCP) and antibody-dependent cellular cytotoxicity (ADCC) in CD47 ⁺/B7-H3 ⁺ tumor cells. VBI-009 inhibits tumor growth in CD47+/B7-H3+ lung cancer xenograft models. VBI-009 can be used for the research of lung cancer .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99740

Mirzotamab	CD276/B7-H3 ADC Antibody	Cancer
Mirzotamab is an IgG1κ monoclonal antibody targeting to *CD276/B7-H3* with anti-tumor activity. Mirzotamab conjugates with Clezutoclax (HY-137774), a BCL inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane research in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted antibody drug conjugate (ADC) .

HY-P99157

Omburtamab	CD276/B7-H3	Cancer
Omburtamab is a humanized monoclonal antibody targeting B7-H3 (CD276). Omburtamab selectively binds to B7-H3 highly expressed on the surface of tumor cells and activates anti-tumor immune responses mediated by T cells and natural killer (NK) cells. Omburtamab can promote the specific infiltration of CAR-T cells into tumors, enhance the killing function of NK cells through the CD16 signaling pathway, and regulate tumor cell glucose metabolism (such as inhibiting the Warburg effect). Omburtamab has the potential to inhibit solid tumors such as non-small cell lung cancer (NSCLC) .

HY-P990279

*Anti-Mouse CD276/B7-H3 Antibody (MJ18)*	CD276/B7-H3 Apoptosis STAT	Inflammation/Immunology Cancer
Anti-Mouse CD276/B7-H3 Antibody (MJ18) is a rat-derived anti-mouse *CD276/B7-H3* IgG1 monoclonal antibody. Anti-Mouse CD276/B7-H3 Antibody (MJ18) can inhibit CD276/B7-H3 and induce tumor cell apoptosis. Anti-Mouse CD276/B7-H3 Antibody (MJ18) enhances anti-tumor immune response by reducing immunosuppressive cells and promoting T cell activation. Anti-Mouse CD276/B7-H3 Antibody (MJ18) can be used for research on cancer such as breast cancer and prostate cancer .

HY-P990340

*Anti-B7-H3/CD276* Antibody**	CD276/B7-H3	Inflammation/Immunology
Anti-B7-H3/CD276 Antibody is a CHO-expressed human antibody targeting *B7-H3/CD276. Anti-B7-H3/CD276* Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-B7-H3/CD276 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992110

Elfetabart DB-1311 Antibody; BNT324 Antibody	CD276/B7-H3	Cancer
Elfetabart is a humanized monoclonal antibody targeting *CD276* with antitumor activity. The antibody isotype of Elfetabart is human IgG1κ, and the recommended isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992158

VBI-009	CD47	Cancer
VBI-009 is a CD47 and B7-H3 (CD276) bispecific antibody. VBI-009 blocks CD47-SIRPα 'don't eat me' signals and restricts activity to CD47 ⁺/B7-H3 ⁺ cells. VBI-009 induces antibody-dependent cellular phagocytosis (ADCP) and antibody-dependent cellular cytotoxicity (ADCC) in CD47 ⁺/B7-H3 ⁺ tumor cells. VBI-009 inhibits tumor growth in CD47+/B7-H3+ lung cancer xenograft models. VBI-009 can be used for the research of lung cancer .

Species:	Human (11) Rat (2) Mouse (2) Cynomolgus (2)
Tag:	His (10) Avi (4) Myc (1) Fc (7)
Source:	HEK293 (17)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70125

	CD276/B7-H3 Protein, Cynomolgus (HEK293, His) rCynCD276/B7-H3, His; CD276 antigen; CD276; B7 homolog 3; B7-H3; CD276; Cynomolgus CD276	Cynomolgus	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. CD276/B7-H3 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD276/B7-H3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70126

	CD276/B7-H3 Protein, Cynomolgus (HEK293, Fc) rCynCD276/B7-H3, Fc; CD276 antigen; CD276; B7 homolog 3; B7-H3; CD276; Cynomolgus CD276 Molecule	Cynomolgus	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. CD276/B7-H3 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived CD276/B7-H3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P7639

	CD276/B7-H3 Protein, Mouse (HEK293, His) 1 Publications Verification rMuB7-H3, His; CD276 antigen; CD276; B7 homolog 3; B7-H3; CD276	Mouse	HEK293
	CD276/B7-H3 Protein, Mouse (HEK293, His) is induced upon T cell activation. B7-H3 selectively increases the production of IFN-γ.

HY-P705245

	CD276/B7-H3 Protein, Mouse (Biotinylated, HEK293, His-Avi) rMuB7-H3, His; CD276 antigen; CD276; B7 homolog 3; B7-H3; CD276	Mouse	HEK293

HY-P700880

	CD276/B7-H3 Protein, Human (Biotinylated, HEK293, C-His-Avi) B7H3; B7-H3; CD276; PSEC0249; UNQ309; PRO352; B7 homolog 3; CD276	Human	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. CD276/B7-H3 Protein, Human (Biotinylated, HEK293, C-His-Avi) is the recombinant human-derived CD276/B7-H3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P70652

	CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (HEK293, His) CD276; B7H34Ig-B7-H3; B7-H3; B7 homolog 3; CD276 antigen; CD276 molecule; Costimulatory molecule	Human	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (HEK293, His) is the recombinant human-derived CD276/B7-H3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P78074

	CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (Biotinylated, HEK293, His-Avi) B7-H3; CD276; PSEC0249; 4Ig-B7-H3; UNQ309; PRO352; B7 homolog 3; CD276	Human	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD276/B7-H3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78930

	CD276/B7-H3 Protein, Human (Biotinylated, HEK293, Fc-Avi) B7-H3; CD276; B7 homolog 3	Human	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. CD276/B7-H3 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived CD276/B7-H3 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag.

HY-P704456

	*FITC-Labeled CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (HEK293, His)* CD276; CD276 molecule; CD276 antigen; B7 H3; B7H3; B7RP 2; B7 homolog 3; costimulatory molecule; B7-H3; B7RP-2; 4Ig-B7-H3;	Human	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. FITC-Labeled CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled CD276/B7-H3 protein, expressed by HEK293, with C-His labeled tag.

HY-P700448

	CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (217a.a, HEK293, Myc-hFc) CD276; CD276 molecule; CD276 antigen; B7 H3; B7H3; B7RP 2; B7 homolog 3; costimulatory molecule; B7-H3; B7RP-2; 4Ig-B7-H3;	Human	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (217a.a, HEK293, Myc-hFc) is the recombinant human-derived CD276/B7-H3 protein, expressed by HEK293 , with C-Myc, C-hFc labeled tag.

HY-P74314

	CD276/B7-H3 Protein, Rat (HEK293, His) B7H3; B7-H3B7 homolog 3; CD276; Costimulatory molecule	Rat	HEK293
	CD276/B7-H3 Protein regulates T-cell-mediated immune responses and transplant rejection. It also promotes bone formation, functioning at the bone-immune interface. Additionally, it activates immune responses against tumors, eliminating them through natural killer cells and CD8 T-cells. Its interaction with TREML2 enhances T-cell activation, highlighting its role in immune regulation. CD276/B7-H3 Protein, Rat (HEK293, His) is the recombinant rat-derived CD276/B7-H3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74315

	CD276/B7-H3 Protein, Rat (HEK293, Fc) B7H3; B7-H3B7 homolog 3; CD276; Costimulatory molecule	Rat	HEK293
	CD276/B7-H3 Protein regulates T-cell-mediated immune responses and transplant rejection. It also promotes bone formation, functioning at the bone-immune interface. Additionally, it activates immune responses against tumors, eliminating them through natural killer cells and CD8 T-cells. Its interaction with TREML2 enhances T-cell activation, highlighting its role in immune regulation. CD276/B7-H3 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD276/B7-H3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74317

	CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (HEK293, hFc) B7H3; B7-H3B7 homolog 3; CD276; Costimulatory molecule	Human	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (HEK293, hFc) is the recombinant human-derived CD276/B7-H3, expressed by HEK293, with C-hFc labeled tag.

HY-P77538

	CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (Biotinylated, HEK293, His) B7H3; B7-H3B7 homolog 3; CD276; Costimulatory molecule	Human	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived CD276/B7-H3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P701302

	*FITC-Labeled CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (HEK293, Fc)* 4Ig-B7-H3; B7-H3; CD276; PSEC0249; UNQ309; PRO352; B7 homolog 3	Human	HEK293
	CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis. It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. FITC-Labeled CD276/B7-H3 (4Ig)/B7-H3b Protein, Human (HEK293, Fc) is the recombinant human-derived FITC-Labeled CD276/B7-H3 protein, expressed by HEK293 , with Fc labeled tag.

HY-P7327

	CD276/B7-H3 Protein, Human (HEK293, His) rHuB7-H3/ICOSLG, His; B7H3; B7 homolog 3; CD276	Human	HEK293
	CD276/B7-H3 Protein, Human (HEK293, His) is a polypeptide chain containing the C-termimal His tag produced in HEK293 cells. B7-H3 is an immune checkpoint from the B7 family of molecules.

HY-P7326

	CD276/B7-H3 Protein, Human (HEK293, Fc) rHuB7-H3/ICOSLG, Fc Chimera; B7H3; B7 homolog 3; CD276	Human	HEK293
	CD276/B7-H3 Protein, Human (HEK293, Fc) is a polypeptide chain containing the C-termimal His tag produced in HEK293 cells. B7-H3 is an immune checkpoint from the B7 family of molecules.

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Host:	Mouse (5) Rabbit (2)
Reactivity:	Human (7) Rat (3) Mouse (3) Monkey (2) Rabbit (2)
Application:	IHC-P (5) ICC/IF (4) WB (4) FC (3) ELISA (5)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (7) Biotin (5)
Clonality:	Monoclonal (5) Recombinant (1)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85833

	CD276/B7H3 Antibody (YA5525) CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD276	WB, ICC/IF, ELISA	Human, Mouse, Rat
	CD276/B7H3 Antibody (YA5525) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD276/B7H3.

HY-P84983

	CD276/B7H3 Antibody (YA4675) CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD antigen CD276; CD276 nanobody; B7H3 nanobody;	ELISA	Human
	CD276/B7H3 Antibody (YA4675) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD276/B7H3.

HY-P85087

	CD276/B7H3 Antibody (YA4779) CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD antigen CD276	WB, IHC-P, ICC/IF, FC, ELISA	Human
	CD276/B7H3 Antibody (YA4779) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD276/B7H3.

HY-P81534

	CD276 Antibody (YA1279) CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD276	IHC-P	Human
	CD276 Antibody (YA1279) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD276.

HY-P81534A

	CD276 Antibody (YA1279)(PBS only) CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD276	IHC-P	Human
	CD276 Antibody (YA1279) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD276.

HY-P84637

	CD276/B7H3 Antibody (YA4334) B7H3; B7-H3; 4Ig-B7-H3; CD276	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Rabbit, Monkey
	CD276/B7H3 Antibody (YA4334) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD276/B7H3.

HY-P84637A

	CD276/B7H3 Antibody (YA4334)(PBS only) B7H3; B7-H3; 4Ig-B7-H3; CD276	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Rabbit, Monkey
	CD276/B7H3 Antibody (YA4334) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD276/B7H3.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

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