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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Ca2 sensitivity
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Ca2 sensitivity" in MCE Product Catalog:
13
7
7 Cited Publications
別名: R-568 hydrochloride; NPS R-568
Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca 2+ .
製品番号: HY-D0077
CAS 番号: 195136-58-4
別名: Oregon green 488
Target:
研究分野:
2',7'-Difluorofluorescein (Oregon green 488) is a fluorescein derivative and a pH-sensitive fluorescent probe (pKa ~4.7). Upon excitation at 488 nm, 2',7'-Difluorofluorescein exhibits pH-sensitive fluorescence intensity through the formation of dianions, while its pH sensitivity decreases under excitation at 450 nm, allowing its use in ratiometric pH analysis. 2',7'-Difluorofluorescein can be used for the quantitative analysis of pH values in the range of 2-7 in submicron aerosol particles. 2',7'-Difluorofluorescein undergoes buffer-mediated and buffer-free excited-state proton transfer between different protonated forms, and its cationic form undergoes rapid excited-state deprotonation. 2',7'-Difluorofluorescein is resistant to photodegradation, maintains stable absorption and fluorescence properties within the physiological pH range, and serves as a fluorescent protein label, a component of Ca 2+ indicators, a fluorescent imaging agent, and an anisotropy probe .
別名: Unoprostone isopropyl ester; UF-021
Target:
研究分野:
Isopropyl unoprostone (Unoprostone isopropyl ester), an analogue of a prostaglandin metabolite, is a potent large conductance Ca 2+-activated K + (BK) channels activator. Isopropyl unoprostone has antiglaucoma effects, lowering intraocular pressure (IOP) by increasing aqueous humour outflow. Isopropyl unoprostone can improve retinal sensitivity and the protection of central retinal sensitivity .
製品番号: HY-10167
CAS 番号: 148717-54-8
別名: R-568; NPS R-568 free base
Tecalcet (R 568), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet (R 568) increases the sensitivity to activation by extracellular Ca 2+ .
製品番号: HY-137704
CAS 番号: 111864-49-4
2′-Deoxy-ADPR is an endogenous TRPM2 agonist that activates Ca 2+-permeable cation channels. 2′-Deoxy-ADPR activates the Ca 2+ sensitivity of TRPM2, increasing whole-cell currents by slowing inactivation and increasing open probability. 2′-Deoxy-ADPR can be used in research related to TRPM2 channel-mediated diseases, such as inflammation and immune-related diseases .
製品番号: HY-D1424
CAS 番号: 123437-32-1
製品番号: HY-P5319
Target:
研究分野:
製品番号: HY-176041
CAS 番号: 1448792-38-8
Target:
研究分野:
Troponin modulator 1 (compound 7) modulates the mutant cardiac muscle thin filament function. Troponin modulator 1 enhances Ca 2+ sensitivity by phosphorylation with an EC50 of 67 μM .
製品番号: HY-101902
CAS 番号: 83104-85-2
別名: Quin-2 acetoxymethyl ester
製品番号: HY-DY1095
CAS 番号: 121714-22-5
別名: Fluo-3-pentaacetoxymethyl ester (solution)
Solvent and concentration: DMSO: 5 mM
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
