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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
CatB
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "CatB" in MCE Product Catalog:
2
2 Cited Publications
Target:
Forschungsgebiete:
Cathepsin inhibitor 1 (Compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively. Cathepsin inhibitor 1 is promising for research of osteoarthritis .
Art. -Nr.: HY-144554
CAS. Nr.: 1779524-93-4
Target:
Forschungsgebiete:
Aminooxy CatB-LXR (compound 10) is a agent-linker conjugates for ADC .
Art. -Nr.: HY-116264
CAS. Nr.: 1417737-67-7
Target:
Forschungsgebiete:
CatB-IN-1 is an enzyme inhibitor with significant inhibitory activity against tumor invasion. CatB-IN-1 may reduce the invasiveness of tumor cells by regulating intracellular protein metabolism. CatB-IN-1 demonstrates effective anti-invasive ability in cell models and can significantly reduce the invasive ability of MCF-10A neoT cells. The structure-activity relationship study of CatB-IN-1 shows that its design can target multiple functions of cat hepsin B .
Art. -Nr.: HY-161596
SmCB1-IN-1 (Compound 2h) is an inhibitor for S. mansoni cathepsin B1 (SmCB1) with an Ki of 0.05 μM . SmCB1-IN-1 exhibits selectivity toward human off-target cathepsins (29% and 37% inhibition for CatB and CatL at 20 μM). SmCB1-IN-1 inhibits 68% Schistosoma mansoni at 1 μM .
Synonyms: Ac-Val-Leu-Pro-Glu(OMe)-CH2F
Ac-VLPE-FMK, a tetrapeptidyl mono-fluoromethyl ketone (m-FMK), is a Cat-B and Cat-L inhibitor. Ac-VLPE-FMK can be used for the research of cancer aggressiveness .
Art. -Nr.: HY-P81502A
Synonyms: CAS2; CatB; GP75; OCA3; TRP1; TYRP; TYRP1; TYRRP; DHICA oxidase
Art. -Nr.: HY-RS15310
Target:
Forschungsgebiete:
TYRP1 Human Pre-designed siRNA Set A contains three designed siRNAs for TYRP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-P73568
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TYRP1; tyrosinase related protein 1; TRP; CAS2; CatB; GP75; OCA3; TRP1; TYRP; b-PROTEIN; brown; isa; MELANOMA ANTIGEN GP75; 5,6-Dihydroxyindole-2-Carboxylic Acid Oxidase; tyrosinase-related protein 1; TRP-1; Tyrp-1; TYRRP
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
