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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
DBM
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "DBM" in MCE Product Catalog:
2
2 Cited Publications
Target:
Áreas de investigación:
DBM-MMAF is a agent-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody agent conjugate (ADC) .
Synonyms: DBM-C5-COOH
Target:
Áreas de investigación:
Dibromomaleimide-C5-COOH (DBM-C5-COOH) is a bifunctional dibromomaleimide (DBM) linker. Dibromomaleimide-C5-COOH can be used to connect MMAF and to synthesize ADC .
Referencia número: HY-160807
No. CAS: 2769152-95-4
Target:
Áreas de investigación:
DBM-GGFG-NH-O-CO-Exatecan (Example 4, Compound 14) is a conjugate of an ADC drug toxin molecule and a linker. DBM-GGFG-NH-O-CO-Exatecan is a complete antibody-drug conjugate intermediate that integrates a potent camptothecin-based toxin, a cleavable peptide linker (GGFG), and a reactive terminus that can directly conjugate to antibodies .
Referencia número: HY-P11112
No. CAS: 1609454-11-6
Áreas de investigación:
Referencia número: HY-164088
No. CAS: 1644228-55-6
Áreas de investigación:
DBM-C5-VC-PAB-MMAE (Compound 3a) is a Drug-Linker conjugate for ADC. DBM-C5-VC-PAB-MMAE is composed of a linker C5-VC-PAB with a maleimide group DBM and an ADC toxin MMAE (HY-15162) .
Target:
Áreas de investigación:
Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol, also known as an anticancer agent that is classified as an alkylating agent. Mitobronitol has potential for myelosuppression associated with significantly decreased risk for several complications of allogeneic bone marrow transplantation in accelerated chronic granulocytic leukemia .
Referencia número: HY-126751
No. CAS: 331686-58-9
Target:
Áreas de investigación:
DBM-819 is a reversible inhibitor of H⁺/K⁺-ATPase (H +/K +-ATPase), with an IC50 value of 5 μM. DBM-819 can reversibly block gastric acid secretion by inhibiting the proton pump in the gastric mucosa. It shows significant protective effects against duodenal ulcers induced by Cysteamine (HY-77591), gastric ulcers induced by Indomethacin (HY-14397), and gastric ulcers induced by Aspirin (HY-14654), with EC50 values of 6, 3.1, and 4 mg/kg respectively. DBM-819 can be used in ulcer prevention research .
Referencia número: HY-110343
No. CAS: 1782532-29-9
Target:
Áreas de investigación:
DBM 1285 dihydrochloride is an orally active TNF-α production inhibitor with anti-inflammatory effects. DBM 1285 dihydrochloride inhibits Lipopolysaccharide (LPS)-induced TNF-α secretion in various cells of macrophage/monocyte lineage .
Referencia número: HY-RS03544
Target:
Áreas de investigación:
DBH Human Pre-designed siRNA Set A contains three designed siRNAs for DBH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-120196
No. CAS: 1904649-00-8
Target:
Áreas de investigación:
CPI703, a BRD inhibitor, binds with residues in domain1 of 5DBM complex .
Referencia número: HY-P86857
Synonyms: dbh antibody; DBM antibody; Dopamine beta hydroxylase antibody; Dopamine beta monooxygenase antibody; Dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody; Dopamine beta-monooxygenase antibody; DOPO_HUMAN antibody; OTTHUMP00000022501 antibody; Soluble dopamine beta-hydroxylase antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
