Dibromomaleimide-C5-COOH
Based on 1 Customer Validation
Dibromomaleimide-C5-COOH (DBM-C5-COOH) is a bifunctional dibromomaleimide (DBM) linker. Dibromomaleimide-C5-COOH can be used to connect MMAF and to synthesize ADC.
For research use only. We do not sell to patients.
- Purity: 99.40%
- CAS No.: 1443214-97-8
- Formula: C10H11Br2NO4
- Molecular Weight:369.01
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1443214-97-8
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Appearance Solid
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Molecular Weight 369.01
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Formula C10H11Br2NO4
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Color White to off-white
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SMILES
O=C(CCCCCN1C(C(Br)=C(C1=O)Br)=O)O
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Synonyms
DBM-C5-COOH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (271.00 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7100 mL | 13.5498 mL | 27.0995 mL | 67.7488 mL |
| 5 mM | 0.5420 mL | 2.7100 mL | 5.4199 mL | 13.5498 mL | |
| 10 mM | 0.2710 mL | 1.3550 mL | 2.7100 mL | 6.7749 mL | |
| 15 mM | 0.1807 mL | 0.9033 mL | 1.8066 mL | 4.5166 mL | |
| 20 mM | 0.1355 mL | 0.6775 mL | 1.3550 mL | 3.3874 mL | |
| 25 mM | 0.1084 mL | 0.5420 mL | 1.0840 mL | 2.7100 mL | |
| 30 mM | 0.0903 mL | 0.4517 mL | 0.9033 mL | 2.2583 mL | |
| 40 mM | 0.0677 mL | 0.3387 mL | 0.6775 mL | 1.6937 mL | |
| 50 mM | 0.0542 mL | 0.2710 mL | 0.5420 mL | 1.3550 mL | |
| 60 mM | 0.0452 mL | 0.2258 mL | 0.4517 mL | 1.1291 mL | |
| 80 mM | 0.0339 mL | 0.1694 mL | 0.3387 mL | 0.8469 mL | |
| 100 mM | 0.0271 mL | 0.1355 mL | 0.2710 mL | 0.6775 mL |