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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
ERp57
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "ERp57" in MCE Product Catalog:
11
Cat. No.: HY-163351
Research Areas:
PDI-IN-2 is a highly selective PDI inhibitor. PDI-IN-2 has an IC50 of 0.63-4.01 μM against human PDI, and exhibits higher targeting specificity compared with ERp57 and ERp72. PDI-IN-2 inhibits platelet aggregation induced by U46619, collagen and tumor cells, and also blocks platelet-promoted tumor cell proliferation as well as the growth of multiple myeloma cells. PDI-IN-2 serves as an important tool reagent for research on multiple myeloma and associated thrombosis .
Category:
Human Gut Microbiota Metabolites Plants Other Families Extract Endogenous metabolite Steroids
Target:
Cat. No.: HY-RS10266
Target:
Research Areas:
PDIA3 Human Pre-designed siRNA Set A contains three designed siRNAs for PDIA3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-151286
CAS No.: 2812356-72-0
Antitumor agent-73 is a Diosgenin (HY-N0177) derivative, which inhibits STAT3 signaling and activates Pdia3/ERp57 exogenously. Antitumor agent-73 shows potent anti-tumor activity against various cancer cell lines, 7.9-341.7-fold stronger than Diosgenin .
Cat. No.: HY-181574
CAS No.: 3097563-91-9
Target:
Research Areas:
PDI-IN-5 (compound 30z) is an allosteric-covalent inhibitor targeting protein disulfide isomerase (PDI) with a 2-chloro-pyrrolopyrimidin-4-one scaffold, with an IC50 of 0.4 μM. PDI-IN-5 exhibits selectivity for ERp57 and GPX4, and inhibits glioblastoma. PDI-IN-5 can be used in glioblastoma-related research .
Cat. No.: HY-RS10268
Target:
Research Areas:
Pdia3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pdia3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10267
Target:
Research Areas:
Pdia3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pdia3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P71148
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PDIA3; Disulfide Isomerase ER-60; Prev. GRP58; ER Protein 60; ERp57; HEL-S-93n; ERp60; Epididymis Secretory Sperm Binding Protein Li 93n; P58; Protein Disulfide Isomerase Family A, Member 3; Protein Disulfide-Isomerase A3; Epididymis Secretory Protein Li
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
