9 Results for "

ERp57

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "ERp57" in MCE Product Catalog:

11
11 Cited Publications
Cat. No.: HY-N0177
CAS No.: 512-04-9
Diosgenin, a steroidal saponin, can inhibit STAT3 signaling pathway . Diosgenin is an exogenous activator of Pdia3/ERp57 . Diosgenin inhibits aortic atherosclerosis progression by suppressing macrophage miR-19b expression .
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Cat. No.: HY-163351
Research Areas:  

Cardiovascular Disease Cancer

PDI-IN-2 is a highly selective PDI inhibitor. PDI-IN-2 has an IC50 of 0.63-4.01 μM against human PDI, and exhibits higher targeting specificity compared with ERp57 and ERp72. PDI-IN-2 inhibits platelet aggregation induced by U46619, collagen and tumor cells, and also blocks platelet-promoted tumor cell proliferation as well as the growth of multiple myeloma cells. PDI-IN-2 serves as an important tool reagent for research on multiple myeloma and associated thrombosis .
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Cat. No.: HY-N0177R
CAS No.: 512-04-9
Diosgenin (Standard) is the analytical standard of Diosgenin. This product is intended for research and analytical applications. Diosgenin, a steroidal saponin, can inhibit STAT3 signaling pathway . Diosgenin is an exogenous activator of Pdia3/ERp57 . Diosgenin inhibits aortic atherosclerosis progression by suppressing macrophage miR-19b expression .
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Cat. No.: HY-RS10266
Research Areas:  

Others

PDIA3 Human Pre-designed siRNA Set A contains three designed siRNAs for PDIA3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-151286
CAS No.: 2812356-72-0
Target:  

STAT

Research Areas:  

Cancer

Antitumor agent-73 is a Diosgenin (HY-N0177) derivative, which inhibits STAT3 signaling and activates Pdia3/ERp57 exogenously. Antitumor agent-73 shows potent anti-tumor activity against various cancer cell lines, 7.9-341.7-fold stronger than Diosgenin .
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Cat. No.: HY-P83555
Synonyms: ERp57; ERp60; ERp61; Glucose Regulated Protein 58 Kd; HsT17083; p58; PDIA3; Phospholipase C alpha; PI PLC

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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Cat. No.: HY-181574
CAS No.: 3097563-91-9
Research Areas:  

Neurological Disease Cancer

PDI-IN-5 (compound 30z) is an allosteric-covalent inhibitor targeting protein disulfide isomerase (PDI) with a 2-chloro-pyrrolopyrimidin-4-one scaffold, with an IC50 of 0.4 μM. PDI-IN-5 exhibits selectivity for ERp57 and GPX4, and inhibits glioblastoma. PDI-IN-5 can be used in glioblastoma-related research .
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Cat. No.: HY-RS10268
Research Areas:  

Others

Pdia3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pdia3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS10267
Research Areas:  

Others

Pdia3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pdia3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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