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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
Eukaryotic initiation factor 2
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "Eukaryotic initiation factor 2" in MCE Product Catalog:
4
4 Cited Publications
Research Areas:
2BAct is a highly selective, orally active, and CNS-penetrant eIF2B (eukaryotic initiation factor 2B) activator with an EC50 of 33 nM. 2BAct prevents neurological defects caused by a chronic integrated stress response. 2BAct displays improved solubility and pharmacokinetics relative to eIF2B activator ISRIB trans-isomer (HY-12495) .
4
4 Cited Publications
Cat. No.: HY-15969
CAS No.: 1164470-53-4
Target:
Research Areas:
Sal003 is a potent, specific and cell-permeable inhibitor of the eukaryotic translation initiation factor 2α (eIF2α) phosphatase. Sal003 is a derivative of salubrinal .
4
2
2 Cited Publications
Cat. No.: HY-P81190
Synonyms: p-PERK(Thr980); PERK(Phospho Thr980); PERK(Phospho T980); mo(Thr980)/hu (Thr982)/rat (Thr974); HRI; HsPEK; Pancreatic eIF2-alpha kinase; PEK; PRKR like endoplasmic reticulum kinase; WRS; DKFZp781H1925; EC 2.7.11.1; EIF2AK3; Eukaryotic translation initiation factor 2 alpha kinase 3; Heme regulated EIF2 alpha kinase.
Research Areas:
EIF2α activator 2 (Compound 1) is an activator of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation. EIF2α activator 2 exhibits high potency in SRB cell proliferation assays (IC50=0.46 μM). EIF2α activator 2 exhibits antiproliferative activity againist K562 and PBMC cells with IC50s of 4.79 and 10.52 μM, respectively .
Cat. No.: HY-174720
Target:
Research Areas:
Human EIF2AK2 mRNA encodes the human eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2) protein, a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. EIF2AK2 plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation.
Cat. No.: HY-P702962
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EIF2S1; Eukaryotic Translation initiation factor 2, Subunit 1 Alpha, 35kDa; Prev. EIF2; EIF2-Alpha; EIF-2alpha; EIF-2A; EIF2A; Eukaryotic Translation initiation factor 2, Subunit 1 (Alpha, 35kD ); Eukaryotic Translation initiation factor 2 Subunit 1; EIF-
Species:
Human
Source:
E. coli
Cat. No.: HY-P705590
Synonyms: EIF2AK4; Eukaryotic Translation initiation factor 2-Alpha Kinase 4; Eukaryotic Translation initiation factor 2 Alpha Kinase 4; Non-Specific Serine/Threonine Protein Kinase; GCN2; General Control Nonderepressible 2; KIAA1338; GCN2 EIF2alpha Kinase; EIF-2-A
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P74422
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: AGO3; Eukaryotic Translation initiation factor 2C 3; Prev. EIF2C3; Argonaute 3; HAGO3; Argonaute3; Eukaryotic Translation initiation factor 2C, 3; EIF-2C 3; Protein Argonaute-3; EIF2C 3; FLJ12765; HAgo3; Eukaryotic Translation initiation factor 2C, 3, Iso
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P83763
Synonyms: EIF 2 alpha antibody;
EIF 2 antibody;
EIF 2A antibody;
EIF 2alpha antibody;
eIF-2-alpha antibody;
eIF-2A antibody;
EIF-2alpha antibody;
EIF2 alpha antibody;
EIF2 antibody;
EIF2A antibody;
EIF2S1 antibody;
Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa antibody;
IF2A_HUMAN antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
