14 Results for "

F-16

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "F-16" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99395
CAS No.: 1826831-79-1
Synonyms: JNJ 56022473; CSL 362

Target:  

Interleukin Related

Research Areas:  

Cancer

Talacotuzumab (JNJ 56022473; CSL 362) is an IgG1-type fully humanized, CD123-neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has KDs of 0.43 nM, 188 nM, 46 nM, 16.8 nM for CD123, CD32b/c, CD16-158F, CD16-158V, respectively. Talacotuzumab inhibits IL-3 binding to CD123, antagonizing IL-3 signaling in target cells. Talacotuzumab has mutated the Fc region to increase affinity for CD16 (FcγRIIIa), thereby enhancing antibody-dependent cell-mediated cytotoxicity (ADCC). Talacotuzumab is highly effective in vivo reducing leukemic cell growth in acute myeloid leukemia (AML) xenograft mouse models .
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Cat. No.: HY-100395
CAS No.: 36098-33-6
Purity:  99.94%
Target:  

Apoptosis

Research Areas:  

Cancer

F16 is a potent growth inhibitor of the neu-overexpressing cells and also selectively inhibits proliferation of mammary epithelial as well as a variety of mouse mammary tumor and human breast cancer cell lines.
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Cat. No.: HY-124866
CAS No.: 922507-80-0
Purity:  ≥98.0%
Target:  

PDI

Research Areas:  

Neurological Disease

PDI-IN-3 (compound 16F16) is a protein disulfide isomerase (PDI) inhibitor. PDI-IN-3 inhibits cell viability .
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Cat. No.: HY-171544
Synonyms: AGS-16M8F
AGS-16C3F is an antibody-drug conjugate (ADC) targeting ENPP3. AGS-16C3F is composed of ENPP3-targeting Anti-ENPP3/CD203c Antibody (HY-P990315) linked to Monomethyl auristatin F (HY-15579) via a linker. AGS-16C3F has anti-tumor activity and can be used in the study of metastatic renal cell carcinoma (mRCC) .
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Cat. No.: HY-P990315
Synonyms: AGS-16C

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-ENPP3/CD203c Antibody (AGS-16C3F antibody) is a humanized antibody expressed in CHO cells, targeting ENPP3/CD203c. Anti-ENPP3/CD203c Antibody contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 154.04 kDa. The isotype control for Anti-ENPP3/CD203c Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-156752
CAS No.: 452919-90-3
Purity:  99.68%
Target:  

Drug Metabolite

Research Areas:  

Others

Cyclosiversioside F 16,25-diacetate (Compound 6), a glycoside, is an alkaline hydrolysis product of Acetyl Derivative (Compound 2) .
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Cat. No.: HY-157292
CAS No.: 3002962-69-5
Research Areas:  

Cancer

2E-3-F16 is a anticancer agent. 2E-3-F16 exhibits tumor cell selectivity between NCI-H446 cancer cells and HBE cells. 2E-3-F16 enhances the sensitivity of A549 cells to Cisplatin (HY-17394) .
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Cat. No.: HY-100395R
CAS No.: 36098-33-6
Research Areas:  

Cancer

F16 (Standard) is the analytical standard of F16 (HY-100395). This product is intended for research and analytical applications. 0
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Cat. No.: HY-149002
CAS No.: 3031403-77-4
Target:  

Topoisomerase Apoptosis

Research Areas:  

Cancer

Topoisomerase I/II inhibitor 4 (compound F16) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 4 inhibits cell proliferation, invasion and migration and induces apoptosis. Topoisomerase I/II inhibitor 4 can be used for liver cancer research .
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Cat. No.: HY-D2310
CXCR2 Probe 1 (Compound [18F]16b) is a selective ligand for CXCR2 and is a radiotracer for PET imaging of neutrophils in inflammatory diseases .
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Cat. No.: HY-W110066
CAS No.: 14916-87-1
Synonyms: F16CuPc (purified by sublimation)
Target:  

MOFs

Research Areas:  

Others

Copper hexadecafluorophthalocyanine (F16CuPc (purified by sublimation)) is a metal-organic framework (MOF).
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Cat. No.: HY-P992067

Research Areas:  

Others

Anti-Human/Monkey NKG2D Antibody (16F16) is an antibody targeting human/monkey NKG2D. The isotype control for Anti-Human/Monkey NKG2D Antibody (16F16) can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-184280
CAS No.: 3128226-38-7
Research Areas:  

Cancer

Anticancer agent 329 is a mitochondria-targeted Podophyllotoxin (HY-15552) derivative conjugated with F16 (HY-100395), and also acts as an anticancer agent. Anticancer agent 329 accumulates in mitochondria and induces Apoptosis in a concentration-dependent manner. Anticancer agent 329 can be used in the research of liver cancer, colorectal cancer, non-small cell lung cancer and breast cancer .
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Cat. No.: HY-P81519
Synonyms: 6-bisphosphatase 1 antibody; 6-bisphosphate 1-phosphohydrolase 1 antibody; D fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody; D-fructose-1 antibody; EC 3.1.3.11 antibody; F16P1_HUMAN antibody; FBP antibody; FBP 1 antibody; FBP1 antibody; FBPase 1 antibody; Fructose 1 6 bisphosphatase 1 antibody; Fructose bisphosphatase 1 antibody; Fructose-1 antibody; Growth inhibiting protein 17 antibody; Liver fructose bisphosphatase antibody;

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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