7 Results for "

FO subunit

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "FO subunit" in MCE Product Catalog:

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57 Cited Publications
Cat. No.: HY-14881
CAS No.: 843663-66-1
Purity:  99.98%
Synonyms: TMC207; R207910
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
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Cat. No.: HY-N125722
CAS No.: 33538-71-5
Synonyms: Aabomycin A1
Venturicidin A (Aabomycin A1) is a natural product derived from Streptomyces, possessing antifungal, anti-Trypanosoma brucei, anti-Leishmania donovani, and ATP synthase inhibitory activities. Venturicidin A acts as an antibiotic adjuvant, promoting the uptake of aminoglycoside antibiotics and enhancing bactericidal efficacy. Venturicidin A inhibits ATP synthesis by blocking proton translocation through the FO subunit. In bloodstream-form Trypanosoma brucei, Venturicidin A causes collapse of the mitochondrial membrane potential; in fungi, it disrupts cell membrane integrity, induces leakage of cytoplasmic contents, elevates ROS levels, and downregulates the expression of fungal pathogenicity-related genes. Venturicidin A exhibits antifungal activity against Botrytis cinerea. Venturicidin A is used in research on bacterial infections, trypanosome/leishmania infections, and gray mold disease .
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Cat. No.: HY-14881R
CAS No.: 843663-66-1
Synonyms: TMC207 (Standard); R207910 (Standard)
Research Areas:  

Infection

Bedaquiline (Standard) is the analytical standard of Bedaquiline. This product is intended for research and analytical applications. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
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Cat. No.: HY-14881S1
CAS No.: 2517573-53-2
Purity:  ≥99.0%
(Rac)-Bedaquiline-d6 is the deuterium labeled Bedaquiline (HY-14881) . Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
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Cat. No.: HY-14881B
CAS No.: 654655-80-8
Synonyms: (Rac)-TMC207; (Rac)-R207910
Target:  

Bacterial

Research Areas:  

Infection

(Rac)-Bedaquiline is the racemate of Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting both the c- and the ε-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
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Cat. No.: HY-14881S2
Bedaquiline impurity 2-d6 is deuterium labeled Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
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Cat. No.: HY-P71550
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ATP5MG; ATP Synthase, H+ Transporting, Mitochondrial FO Complex, subunit G; Prev. ATP5L; F1FO-ATP Synthase Complex FO Membrane Domain G subunit; ATP5JG; ATP Synthase subunit G, Mitochondrial; ATP Synthase, H+ Transporting, Mitochondrial F0 Complex, Subuni
Species:  
Bovine
Source:  
E. coli
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