13 Results for "

FSHR

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "FSHR" in MCE Product Catalog:

1
ML224
ML224
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1 Cited Publications
Cat. No.: HY-12381
CAS No.: 1338824-21-7
Purity:  99.18%
Synonyms: NCGC00242364; ANTAG3
Target:  

TSH Receptor

Research Areas:  

Endocrinology

ML224 (NCGC00242364) is a selective TSHR antagonist with an IC50 value of 2.1 µM. ML224 can be used in the study of Graves' disease and other thyroid disorders.
FSHR agonist 1
FSHR agonist 1
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Cat. No.: HY-150210
CAS No.: 1256776-89-2
Purity:  98.48%
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

FSHR agonist 1 is a high affinity and allosteric follicle stimulating hormone receptor (FSHR) agonist with a pEC50 of 7.72. FSHR agonist 1 formes extensive interactions with the TMD to directly activate FSHR .
Fsh receptor-binding inhibitor fragment(bi-10)
Fsh receptor-binding inhibitor fragment(bi-10)
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Cat. No.: HY-P4190
CAS No.: 163973-98-6
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

FSH receptor-binding inhibitor fragment(bi-10) is a potent FSH antagonist. FSH receptor-binding inhibitor fragment(bi-10) blocks the binding of FSH to FSHR, and alteres FSH action at the receptor level. FSH receptor-binding inhibitor fragment(bi-10) results in the suppression of ovulation and causes follicular atresia of mice. FSH receptor-binding inhibitor fragment(bi-10) has the potential for utilizing to restrain the carcinogenesis of ovarian cancer by down-regulating overexpression of FSHR and ERβ in the ovaries .
TOP5668
TOP5668
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Cat. No.: HY-160857
CAS No.: 1850256-71-1
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

TOP5668 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5668 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats .
ADX61623
ADX61623
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Cat. No.: HY-164764
CAS No.: 1067189-44-9
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

ADX61623 is a potent follicle stimulating hormone (FSH) receptor (FSHR) negative allosteric modulator (NAM). ADX61623 shows luteinizing hormone receptor (LH-R) activity and is not active on thyroid-stimulating hormone (TSH) receptors. ADX61623 can be used for the study of estrogen dependent disease .
TOP5300
TOP5300
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Cat. No.: HY-160856
CAS No.: 1848981-48-5
Synonyms: TOP05300
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

TOP5300 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5300 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats .
RFRP-3 (mouse)
RFRP-3 (mouse)
0 Images
Cat. No.: HY-P10780
Synonyms: Neuropeptide NPVF (mouse)
Target:  

Neuropeptide FF Receptor Apoptosis MDM-2/p53 PERK

Research Areas:  

Endocrinology

RFRP-3 (mouse) is a functional ortholog of avian gonadotropin inhibitory hormone (GnIH), binding to GPR147. RFRP-3 (mouse) reduces Progesterone synthesis by inhibiting FSHR and key enzymes involved in steroidogenesis (P450scc, 3β-HSD, StAR). RFRP-3 (mouse) induces Apoptosis (increase of p53). RFRP-3 (mouse) also suppresses the ERK signaling pathway. RFRP-3 (mouse) can be used for research of follicular development .
FSHR Human Pre-designed siRNA Set A
FSHR Human Pre-designed siRNA Set A
Cat. No.: HY-RS05124
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

FSHR Human Pre-designed siRNA Set A contains three designed siRNAs for FSHR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fshr Rat Pre-designed siRNA Set A
Fshr Rat Pre-designed siRNA Set A
Cat. No.: HY-RS23431
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

Fshr Rat Pre-designed siRNA Set A contains three designed siRNAs for Fshr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fshr Mouse Pre-designed siRNA Set A
Fshr Mouse Pre-designed siRNA Set A
Cat. No.: HY-RS16988
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

Fshr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fshr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

FSHR Protein, Human (His)
FSHR Protein, Human (His)
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Cat. No.: HY-P72198
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Follicle stimulating hormone receptor; Follicle stimulating hormone receptor isoform 1; Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; FSHR; FSHR_HUMAN; FSHRO; LGR1; MGC141667; MGC141668; ODG1; ovarian dysgenesis 1
Species:  
Human
Source:  
E. coli
Org 214444-0
Org 214444-0
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Cat. No.: HY-182705
CAS No.: 914093-78-0
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

Org 214444-0 is an orally active, nanomolar-potent and selective FSHR agonist, with EC50 values of 2.0 nM and 1.2 nM in human and rat (measured in CHO cells). Org 214444-0 activates human granulosa cells in vitro, supports rat follicular development and induces ovulation in vivo. Org 214444-0 can be used for the research of infertility .
ADX68692
ADX68692
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Cat. No.: HY-W673613
CAS No.: 1067191-08-5
Target:  

Estrogen Receptor/ERR

Research Areas:  

Metabolic Disease

ADX68692 is an orally active negative allosteric modulators of follicle-stimulating hormone receptor with a log IC50 of -5.71. ADX68692 can inhibit hCG-induced cAMP production and s ß-arrestin 2 recruitment in HEK293 cells. ADX68692 exhibits a partial effect in both mLTC-1 and primary rat Leydig cells. ADX68692 inhibits FSHR-promoted cAMP, progesterone and estradiol production. ADX68692 can reduce the number of oocytes recovered from the ampullae .
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