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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
FSHR
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "FSHR" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: NCGC00242364; ANTAG3
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ML224 (NCGC00242364) is a selective TSHR antagonist with an IC50 value of 2.1 µM. ML224 can be used in the study of Graves' disease and other thyroid disorders.
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FSHR agonist 1 is a high affinity and allosteric follicle stimulating hormone receptor (FSHR) agonist with a pEC50 of 7.72. FSHR agonist 1 formes extensive interactions with the TMD to directly activate FSHR .
Cat. No.: HY-P4190
CAS No.: 163973-98-6
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Cat. No.: HY-160857
CAS No.: 1850256-71-1
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TOP5668 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5668 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats .
Cat. No.: HY-164764
CAS No.: 1067189-44-9
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ADX61623 is a potent follicle stimulating hormone (FSH) receptor (FSHR) negative allosteric modulator (NAM). ADX61623 shows luteinizing hormone receptor (LH-R) activity and is not active on thyroid-stimulating hormone (TSH) receptors. ADX61623 can be used for the study of estrogen dependent disease .
Cat. No.: HY-160856
CAS No.: 1848981-48-5
Synonyms: TOP05300
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TOP5300 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5300 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats .
Cat. No.: HY-P10780
Synonyms: Neuropeptide NPVF (mouse)
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Cat. No.: HY-RS05124
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FSHR Human Pre-designed siRNA Set A contains three designed siRNAs for FSHR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23431
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Fshr Rat Pre-designed siRNA Set A contains three designed siRNAs for Fshr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16988
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Fshr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fshr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P72198
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FSHR; FSHRO; Prev. ODG1; FSH Receptor; LGR1; FSHR1; Follicle-Stimulating Hormone Receptor; FSH-R; Follitropin Receptor; Follicle Stimulating Hormone Receptor; LRRNT Domain-Containing Protein
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Human
Source:
E. coli
Cat. No.: HY-W673613
CAS No.: 1067191-08-5
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ADX68692 is an orally active FSHR negative allosteric regulator, with an IC50 value of 140 nM against hFSHR. ADX68692 antagonizes hCG (HY-107953)-mediated cAMP production, β-arrestin 2 recruitment, and the LH/CGR signaling pathway. ADX68692 partially inhibits testosterone synthesis. ADX68692 blocks follicle growth, disrupts the estrous cycle in rats, and reduces the pregnancy rate in rats. ADX68692 can be used in research related to contraception and endometriosis .
Cat. No.: HY-182705
CAS No.: 914093-78-0
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Org 214444-0 is an orally active, nanomolar-potent and selective FSHR agonist, with EC50 values of 2.0 nM and 1.2 nM in human and rat (measured in CHO cells). Org 214444-0 activates human granulosa cells in vitro, supports rat follicular development and induces ovulation in vivo. Org 214444-0 can be used for the research of infertility .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
