15 Results for "

FUS

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "FUS" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-147410
CAS No.: 2589926-25-8
Synonyms: ION-363
Target:  

DNA/RNA Synthesis

Research Areas:  

Neurological Disease

Ulefnersen (ION363) is an Antisense Oligonucleotide (ASO) directed against the 6th intron of the fused-in sarcoma (FUS) transcript to silence FUS in a non-allele-specific manner. Ulefnersen can reduce postnatal levels of FUS protein in the brain and spinal cord in disease-relevant mouse model of ALS-FUS , delaying motor neuron degeneration. Ulefnersen can be used in the research of Amyotrophic Lateral Sclerosis (ALS) .
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1
1 Cited Publications
Cat. No.: HY-147410A
CAS No.: 2589926-27-0
Purity:  94.55%
Synonyms: ION-363 sodium
Target:  

DNA/RNA Synthesis

Research Areas:  

Neurological Disease

Ulefnersen sodium (ION363) is an Antisense Oligonucleotide (ASO) directed against the 6th intron of the fused-in sarcoma (FUS) transcript to silence FUS in a non-allele-specific manner. Ulefnersen sodium can reduce postnatal levels of FUS protein in the brain and spinal cord in disease-relevant mouse model of ALS-FUS , delaying motor neuron degeneration. Ulefnersen sodium can be used in the research of Amyotrophic Lateral Sclerosis (ALS) .
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Cat. No.: HY-P10580
CAS No.: 1359657-45-6
Vasculotide is a blood-brain barrier (BBB)-penetrant Tie2 agonist. Vasculotide binds to a unique domain of Tie2, induces receptor clustering to drive phosphorylation, activates downstream PI3K/Akt and eNOS pathways, enhances inter-endothelial cell junctions (such as VE-cadherin and claudin-5), and inhibits inflammatory adhesion molecules, ultimately stabilizing the vascular endothelial barrier and reducing its permeability . Vasculotide alleviates pulmonary microvascular leakage and microcirculatory dysfunction caused by cardiopulmonary bypass, acts as an adjuvant radioprotective agent to reduce acute radiation dermatitis, and promotes BBB recovery after focused ultrasound (FUS). Combination of Vasculotide with antibiotics reduces lung injury .
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Cat. No.: HY-P10580A
Vasculotide TFA is a blood-brain barrier (BBB)-penetrant Tie2 agonist. Vasculotide TFA binds to a unique domain of Tie2, induces receptor clustering to drive phosphorylation, activates downstream PI3K/Akt and eNOS pathways, enhances inter-endothelial cell junctions (such as VE-cadherin and claudin-5), and inhibits inflammatory adhesion molecules, ultimately stabilizing the vascular endothelial barrier and reducing its permeability . Vasculotide TFA alleviates pulmonary microvascular leakage and microcirculatory dysfunction caused by cardiopulmonary bypass, acts as an adjuvant radioprotective agent to reduce acute radiation dermatitis, and promotes BBB recovery after focused ultrasound (FUS). Combination of Vasculotide TFA with antibiotics reduces lung injury .
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Cat. No.: HY-P11231
CAS No.: 2780353-11-7
Synonyms: FUS(364-369)-TAT
Target:  

Peptides

Research Areas:  

Cancer

β4-TAT is a kind of β-sheet peptide foldamer. β4-TAT is composed of two parts: the β4 sequence (derived from the β-sheet fragment of the RRM domain of fused in sarcoma (FUS)) and the TAT sequence (a nuclear localization signal peptide that helps the entire peptide penetrate the nuclear membrane). β4-TAT influences FUS aggregation by targeting its RNA recognition motifs (RRM). β4-TAT effectively induces FUS aggregation within cells, leading to the death of cancer cells. β4-TAT can be used for the study of FUS .
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Cat. No.: HY-RS05149
Research Areas:  

Others

FUS Human Pre-designed siRNA Set A contains three designed siRNAs for FUS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23813
Research Areas:  

Others

Fus Rat Pre-designed siRNA Set A contains three designed siRNAs for Fus gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17359
Research Areas:  

Others

Fus Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fus gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P83452
Synonyms: FUS; FUS-CHOP; TLS; 75 kDa DNA-pairing protein; Oncogene FUS; Oncogene TLS; POMP75; Translocated in liposarcoma protein

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P86540

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P702630
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RNA-binding protein FUS; 75 kDa DNA-pairing protein; Oncogene FUS; Oncogene TLS; POMp75; Translocated in liposarcoma protein; TLS
Species:  
Source:  
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Cat. No.: HY-P704622
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: RNA-binding protein FUS; 75 kDa DNA-pairing protein; Oncogene FUS; Oncogene TLS; POMp75; Translocated in liposarcoma protein; TLS
Species:  
Source:  
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Cat. No.: HY-P83340
Synonyms: BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86FUS; HEL-249

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse

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Cat. No.: HY-P83340A
Synonyms: BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86FUS; HEL-249

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse

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Cat. No.: HY-P810358
Synonyms: Activating transcription factor 1, ATF 1, atf1, ATF1 EWS FUSion gene, ATF1 FUS FUSion gene, ATF1_HUMAN, cAMP dependent transcription factor 1, cAMP-dependent transcription factor ATF-1, Cyclic AMP dependent transcription factor ATF 1, Cyclic AMP dependent transcription factor ATF1

Host:  

Rabbit

Application:  

WB, ICC/IF, IF-Tissue, IHC-P, FC

Reactivity:  

Human

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